Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06766253Recruiting
Comparing three breathing tube devices for head-down laparoscopic surgery
This study is comparing three different breathing tube devices (GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask) for people having laparoscopic surgery while tilted head-down. The goal is to see which device works best and most safely.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06776705Recruiting
Low-intensity ultrasound for sleep problems in chronic tinnitus
This trial tests if a gentle ultrasound treatment can improve sleep in people with ongoing tinnitus. It focuses on older adults who have had tinnitus for at least 3 months and struggle with sleep.
Hong Kong, Hong KongAges 60–85 - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT06781749Recruiting
Measuring social engagement in older adults with hearing loss
This study tests a new way to objectively measure how socially engaged older adults with hearing loss are. It may help researchers better understand the impact of hearing loss on social participation.
Los Angeles, CaliforniaAges 60 years+ - NCT06782308Recruiting
Tinnitus patient preferences survey
This study surveys adults with chronic, bothersome tinnitus to understand their treatment preferences. If you have had tinnitus for three months or longer, your input could help shape future therapies.
New York, New YorkAges 18 years+ - NCT06796270Recruiting
Short-course radiation for nasopharyngeal cancer
This trial tests a shorter course of radiation therapy for people with nasopharyngeal cancer, a type of head and neck cancer. The goal is to see if a hypofractionated (fewer, larger doses) approach is safe and effective.
Haikou, HainanAges 18–75 - NCT06801522RecruitingPhase 2/Phase 3
Nasal spray comparison during breathing tube placement
This trial compares two nasal medications (adrenaline and xylometazoline) to see which one reduces bleeding better when placing a breathing tube through the nose. It may help people undergoing planned mouth or jaw surgery.
Karachi, SindhAges 18–60 - NCT06802835RecruitingPhase 1/Phase 2
EGFR antibody plus immunotherapy and chemo for advanced nasopharyngeal cancer
This trial tests a combination of an EGFR antibody, a PD-1 inhibitor, and chemotherapy for people with nasopharyngeal cancer that has returned or spread after initial treatment. The goal is to see if this new mix can help shrink tumors or slow the disease.
Guangzhou, GuangdongAges 18–75 - NCT06803095Recruiting
Walking with a dog for tinnitus relief in sleep apnea
This study tests whether walking with a dog can help reduce tinnitus complaints in people who have mild sleep apnea and are overweight. It aims to see if this simple, enjoyable activity can improve your symptoms.
Dokki, Giza GovernorateAges 30–45 - NCT06811610Recruiting
Testing a hearing device with noise-canceling headphones
This trial tests if a portable hearing device using active noise-canceling headphones can accurately measure hearing. It might help by making hearing tests more convenient and accessible.
Xi’an, ShanxiAges 6 years+ - NCT06811844RecruitingPhase 2
Shorter chemo plus immunotherapy for advanced nasopharyngeal cancer
This trial tests a shorter course of chemotherapy combined with an immunotherapy drug (camrelizumab) for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if this approach works well while reducing treatment side effects.
Xiamen, FujianAges 18–65 - NCT06813677Recruiting
Innsbruck Health Promotion Program
This study is a health promotion program for people living in the Innsbruck area. It aims to help participants improve their overall health and well-being.
InnsbruckAges 18 years+ - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT06817707Recruiting
Bladder function study in CANVAS patients
This study looks at bladder problems in people with CANVAS, a rare genetic condition that affects nerves. You will have an ultrasound of your bladder and a test to measure your urine flow.
Nice, Alpes MaritimesAges 18 years+ - NCT06821243Recruiting
Finding markers in HPV-related throat cancer to guide treatment
This study looks for certain markers in people with HPV-related throat cancer that could help doctors choose the best treatment. If you are planning to have surgery for your throat cancer, you may be able to join.
Rome, RomeAges 18 years+ - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+ - NCT06829147Recruiting
AI to diagnose lymph node spread in nasopharyngeal cancer
This trial tests whether a computer model can accurately detect if cancer has spread to lymph nodes in patients with nasopharyngeal carcinoma. It uses MRI and PET/CT scans taken before treatment to see if the AI can replace or supplement current methods.
Guangzhou, GuangdongAges Any age - NCT06830109RecruitingPhase 2
Testing a nasal spray for stuffy nose relief
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
St Louis, MissouriAges 18 years+ - NCT06830174Recruiting
tDCS Brain Stimulation for Laryngeal Dystonia
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
New Haven, ConnecticutAges 18–65 - NCT06830187Recruiting
Bone density, vitamin D, and hearing loss in otosclerosis
This study looks at how bone density and vitamin D levels relate to hearing loss in people with otosclerosis, a condition where extra bone growth in the ear causes hearing problems. It may help doctors understand why some people lose more hearing than others.
AnkaraAges 18 years+ - NCT06839066RecruitingPhase 2
HLX43 for advanced nasopharyngeal cancer after prior treatments
This trial tests an investigational drug called HLX43 for people with nasopharyngeal cancer that has come back or spread, and who have already tried two or more prior treatments without success. The goal is to see if HLX43 can shrink tumors or slow the cancer's growth.
Fuzhou, FujianAges 18 years+ - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75 - NCT06844071Recruiting
Safety of Sentio bone conduction implant in teens
This study tests the safety and performance of the Sentio bone conduction implant (a device that helps you hear by sending sound through the skull) in teenagers aged 12 to 17. It may be an option if you have certain types of hearing loss that cannot be helped by regular hearing aids.
Atlanta, GeorgiaAges 12–18 - NCT06844461Recruiting
Quality of life after acoustic neuroma treatment
This study looks at how acoustic neuroma and its treatments affect your quality of life, and whether you later regret the choices you made. Researchers want to know if follow-up or surgery makes a difference.
BolognaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.