Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06614582Enrolling by invitation
Long-term nose tube study for children with weak muscle tone
This study looks at the long-term safety and effectiveness of a nose tube (nasopharyngeal airway) for children who have obstructive sleep apnea due to weak muscle tone. It's for children who already used this device in a previous study.
Ann Arbor, MichiganAges 3–23 - NCT06603935Enrolling by invitation
Digital medicine for allergic rhinitis management
This trial tests a digital platform to help manage allergic rhinitis (nasal allergies) and sinusitis. It's for adults whose symptoms are not well controlled despite treatment.
West Palm Beach, FloridaAges 18–65 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06563960Enrolling by invitation
Carbonated water for safer swallowing
This trial tests if carbonated water can help people who have swallowing problems (when liquid goes into the airway instead of the stomach). You will be given carbonated water and a swallowing exam to see if it reduces risk.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06475365Enrolling by invitation
Salt water gargling after neck surgery to help swallowing
This study tests whether gargling with salt water after multi-level neck fusion surgery can improve swallowing recovery. If you are having this surgery, the trial aims to find a simple, low-cost way to protect your swallowing function.
Los Angeles, CaliforniaAges 18–80 - NCT06471309Enrolling by invitation
Theta burst TMS for swallowing problems after stroke
This trial tests a type of brain stimulation called theta burst transcranial magnetic stimulation (TMS) to see if it can help people who have trouble swallowing after a stroke. It is designed for people who had their first stroke within the last 2 weeks to 6 months and are right-handed.
Zhengzhou, HenanAges 18–80 - NCT06464835Enrolling by invitation
Brain stimulation and swallowing therapy for post-stroke swallowing problems
This trial tests whether combining two types of brain stimulation (iTBS and NMES) can improve swallowing problems after a stroke. If you have had trouble swallowing for at least two weeks but no longer than six months after your stroke, you may be able to join.
Zhengzhou, HenanAges 18–80 - NCT06355102Enrolling by invitation
Study of tinnitus after sudden hearing loss using brain scans
This study uses brain imaging (fMRI) and blood tests to understand why some people with sudden hearing loss develop tinnitus (ringing in the ears) while others do not. It may help researchers find better ways to prevent or treat tinnitus.
Nanjing, JiangsuAges 18–65 - NCT06305039Enrolling by invitation
Better hearing with two cochlear implants
This study tests how well people with two cochlear implants (or one cochlear implant and one hearing ear) can hear in complex, noisy settings. It aims to improve how these devices help in everyday listening situations.
Bethesda, MarylandAges 18–85 - NCT06251817Enrolling by invitation
Wideband ear sound test in Thai adults
This study measures how sound travels through the ear in Thai adults with normal hearing or conductive hearing loss. The results will help doctors better understand ear function and improve diagnosis.
Khon KaenAges 18–59 - NCT05870527Enrolling by invitation
Pupil changes during vagus nerve stimulation during ear surgery
This study looks at how your pupils (the black center of the eye) respond while a vagus nerve device is turned on during surgery for either a cochlear implant or a vagus nerve stimulator. It aims to better understand the eye/nerve effects of this stimulation, which may improve how such procedures are done safely.
New York, New YorkAges 18 years+ - NCT05859568Enrolling by invitation
Hearing device fit checks and baseline performance study
This study measures how well hearing devices work and how they are best fitted at the start. It helps the company collect baseline information so future testing and fitting can be improved.
Valencia, CaliforniaAges 8 years+ - NCT05762055Enrolling by invitation
Compare two neck fusion methods for arthritis pain
This study compares two ways of doing neck fusion surgery for people with age-related (degenerative) problems in the cervical spine. It may help surgeons learn which method works best for healing and long-term outcomes.
Dallas, TexasAges 18–99 - NCT05554692Enrolling by invitation
Study how aging and cochlear implants affect speech timing
This study looks at how the brain processes the timing of sounds and speech in people with cochlear implants and in people with typical hearing. It may help researchers understand what changes with age and how implant hearing works in the real world.
College Park, MarylandAges 18–85 - NCT05531630Enrolling by invitation
Xylitol versus saline rinses for sinus symptoms in adults with CF
This study compares two kinds of nasal rinse packets—xylitol versus plain saline—to see which better reduces sinus symptoms. It may help adults with cystic fibrosis and long-term sinus inflammation feel better with routine, at-home nasal care.
LeuvenAges 18 years+ - NCT05497219Enrolling by invitation
Testing normal swallowing measurements using video X-rays
This study helps researchers create reference (baseline) values for how swallowing looks on video X-ray. You may qualify if you have no swallowing problems, or if you have a diagnosed swallowing-related condition with significant symptoms.
Gainesville, FloridaAges 18 years+ - NCT05176561Enrolling by invitation
Brain and hearing training for older cochlear-implant users
This trial studies whether a structured auditory (hearing) and cognitive (thinking) training program can improve outcomes for adults who use cochlear implants. It’s designed for people at a certain stage after their implant and with specific hearing and thinking test results.
Washington D.C., District of ColumbiaAges 60 years+ - NCT05110183Enrolling by invitation
Bionic ear implant surgery for certain inner-ear nerve tumors
This study looks at a special “opto-electrical” cochlear implant for people who need a specific type of tumor-removal surgery near the facial nerve and hearing structures. It may help restore hearing in people whose hearing is already severely reduced and who meet the tumor and hearing-size criteria.
Coral Gables, FloridaAges 18–89 - NCT04673565Enrolling by invitation
Coaching new hearing-aid users to use them more
This study tests whether motivational interviewing (a supportive coaching conversation) can help people who are new to hearing aids wear and use them more successfully. It uses online questionnaires to understand hearing-aid use and comfort.
Vancouver, British ColumbiaAges 18 years+ - NCT04672174Enrolling by invitation
Cognitive screening study for adults with hearing loss
This study checks how well people with hearing loss perform on thinking and memory tests (cognitive screening). It may help researchers find better ways to spot thinking changes in people with hearing loss and understand what factors are involved.
Zurich, Canton of ZurichAges 50–90 - NCT04382807Enrolling by invitation
Online group counseling for long-term ringing in the ears
This trial tests an internet-based group counseling program for people who have had ongoing (chronic) tinnitus—ringing or other sounds in the ears. It may help you learn coping strategies and reduce how much the condition affects your daily life.
AntwerpAges 18 years+ - NCT04266093Enrolling by invitation
Gene therapy follow-up for adults previously treated at NCI
This study is a follow-up check for people who were previously enrolled in certain NCI gene therapy treatment studies. It helps the research team monitor long-term effects and outcomes after treatment.
Bethesda, MarylandAges 18–120 - NCT04194216Enrolling by invitationPhase 3
Antibiotic prevention during rhinoplasty surgery
This trial studies whether giving antibiotics before and around rhinoplasty (nose reshaping) can lower the risk of infection. If you qualify, you may be randomized to receive antibiotic prevention or another approach to prevention.
Stanford, CaliforniaAges 18 years+ - NCT04074356Enrolling by invitation
Tests for esophagus function using noninvasive body measurements
This study looks for noninvasive ways to measure how well your esophagus is moving. It may help doctors better evaluate swallowing and esophagus movement without relying only on invasive testing.
Nashville, TennesseeAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.