Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07423429Recruiting
Switching to Aflibercept 8 mg for wet AMD
This trial tests if switching to a higher dose of aflibercept (Eylea) can help people with wet age-related macular degeneration (AMD) who need frequent eye injections. If you've been on other anti-VEGF injections for over a year and still need them more often than every 12 weeks, this study might offer a new option.
Nantes, NantesAges 18 years+ - NCT07424755Recruiting
AI eye test for cataract with high nearsightedness
This trial uses an artificial intelligence system to analyze detailed eye images from people who have both cataracts and severe nearsightedness (high myopia) with a specific eye shape (posterior staphyloma). The goal is to see if the AI can help doctors better understand and manage these conditions.
ShanghaiAges Any age - NCT07417046Recruiting
Fluoxetine and eye patching for lazy eye treatment
This study tests whether a combination of a medicine (fluoxetine) and eye patching can improve vision in people with lazy eye (amblyopia). It uses special eye scans and brain wave tests to see how well the treatment works for different ages.
Minya, Minya GovernorateAges 10 years+ - NCT07425535RecruitingEarly Phase 1
Optic nerve strain study for people without glaucoma
This study looks at how the optic nerve (the part of your eye that sends images to your brain) strains or bends in people who do not have glaucoma. It uses advanced eye imaging and home pressure checks to understand the nerve's health.
Baltimore, MarylandAges 30–90 - NCT05941182Recruiting
Remote eye follow-up using Vision self-testing
This trial looks at a real-world way to run remote (video/online) eye clinic follow-up visits that include self-testing. It may help your care be more convenient while still supporting proper eye checks from home.
Cambridge, CambridgeshireAges 4 years+ - NCT07408232RecruitingPhase 1/Phase 2
Gene therapy for retinitis pigmentosa from RHO gene changes
This trial tests an experimental gene therapy for people with a specific type of retinitis pigmentosa caused by a change in the RHO gene. The therapy is given in multiple doses to see if it is safe and helpful.
Portland, OregonAges 18 years+ - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07410637Recruiting
Thyroid hormones and energy in graves' or thyroid cancer
This trial studies how thyroid hormone levels affect your body's use of sugar and energy. It may help people newly diagnosed with Graves' disease or thyroid cancer understand their metabolism better.
Ulm, Baden-WurttembergAges Any age - NCT07409077Recruiting
Biofeedback training for glaucoma patients
This study tests if biofeedback training—a technique that helps you learn to use your remaining vision better—can improve vision in people with glaucoma. It focuses on those with vision loss near the center of their sight.
Toronto, OntarioAges Any age - NCT07410039RecruitingPhase 4
Acute treatment for neuromyelitis optica in real-world setting
This study looks at treatments for people with neuromyelitis optica spectrum disorder (NMOSD) who are having a sudden attack affecting their vision or spinal cord. It aims to find out which treatments work best in everyday practice.
BeijingAges 18–65 - NCT07408154Recruiting
Direct vs standard laser for glaucoma: which works better?
This study compares a direct laser treatment to the standard laser for glaucoma or high eye pressure. It aims to see if the direct method is just as effective and possibly safer.
Charleston, South CarolinaAges 18 years+ - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT06812845Recruiting
Eye disease patterns at Sohag University Hospital
This study looks at the different types of eye diseases in people who visit the eye testing unit. It helps doctors understand what conditions are most common so they can improve care.
SohagAges Any age - NCT01485575Recruiting
Blue or green dye eye surgery to help remove retinal tissue
This trial studies an eye surgery technique that uses a colored dye (blue or green) to help the surgeon carefully remove a thin inner retinal layer. It may help make the procedure more precise and safer, and the study compares how the dye-assisted method works.
LinzAges 18 years+ - NCT06345976Recruiting
How albinism affects daily vision and activities
This study is for adults with any type of albinism. It looks at how albinism affects your everyday vision and activities through a simple questionnaire.
ParisAges 18 years+ - NCT07400965RecruitingPhase 2
Testing a new eye drop for eyelid inflammation caused by tiny mites
This trial tests an investigational eye drop (GLK-321) to see if it safely and effectively treats Demodex blepharitis, an eyelid inflammation caused by tiny mites. It may help people who have signs of this condition and good enough vision.
Newport Beach, CaliforniaAges 18 years+ - NCT07400926Recruiting
Study of a new inserter for a glaucoma implant
This trial is testing a new way to deliver a medication (travoprost) directly into the eye using a small implant. It's for people with open-angle glaucoma and aims to see how well the updated inserter works.
Kenosha, WisconsinAges 18 years+ - NCT07402876RecruitingPhase 3
Trial for primary vitreoretinal lymphoma treatment
This trial tests a treatment for primary vitreoretinal lymphoma, a rare eye cancer. It aims to see if the drug methotrexate can help patients with this condition.
Miami, FloridaAges 21 years+ - NCT07400952RecruitingPhase 2
Testing GLK-221 Eye Drops for Keratoconus
This study tests an eye drop called GLK-221 for people with keratoconus, a condition where the clear front of the eye bulges. The goal is to see if the drops can safely help improve the condition compared to a placebo (an inactive solution).
Westerville, OhioAges 18–55 - NCT07404111RecruitingPhase 1/Phase 2
Study of VV-14305 for thyroid eye disease
This study tests an investigational medication for thyroid eye disease, which causes bulging eyes and discomfort. The treatment is given as an injection near the eye, and the study will last about 12 months to see how safe and effective it is.
Livonia, MichiganAges 18–80 - NCT07400757Recruiting
Statin and vitamin D for active thyroid eye disease
This trial tests whether a statin (a cholesterol-lowering medicine) combined with vitamin D can improve active thyroid eye disease. It may help if you have both eye inflammation and high cholesterol.
Taipei, TaiwanAges 20 years+ - NCT07403825RecruitingPhase 4
Faricimab for wet AMD with subretinal material
This trial tests a new drug called Faricimab for people with a specific type of wet age-related macular degeneration (AMD) that has a buildup of material beneath the retina. The goal is to see if Faricimab can help clear this material and improve vision.
Córdoba, AndalusiaAges 50 years+ - NCT07400224RecruitingPhase 1/Phase 2
New PET imaging test for cancer, heart, or immune disease
This study tests a new type of PET scan using a special tracer called Al18F-NOTA-FAPI-04 to see if it can better detect cancer, heart disease, or immune system conditions. The goal is to find out how well this imaging method works for diagnosis or monitoring of these diseases.
BeijingAges 18–88
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.