Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07390500RecruitingPhase 2
Myopia control study for children using digital devices
This study tests a special lens designed to slow down nearsightedness (myopia) in children. It is for kids who spend at least one hour a day on screens and currently wear regular glasses.
RehovotAges 6–12 - NCT06830551Recruiting
Cord blood serum eye drops for severe eye problems from anti-EGFR treatment
This trial tests whether cord blood serum eye drops can help with severe dry eye or corneal damage caused by anti-EGFR cancer treatment. If you have advanced cancer with an EGFR mutation and are struggling with eye irritation or vision problems from your medication, this study might offer a new way to help.
BolognaAges 18 years+ - NCT07389980RecruitingPhase 3
Personalized high-dose aflibercept for a type of wet AMD
This trial tests a higher dose of aflibercept (a drug that blocks abnormal blood vessel growth) for people with a specific form of wet age-related macular degeneration called polypoidal choroidal vasculopathy. The goal is to see if a personalized treatment plan with this stronger dose is safe and effective for those who have not been treated before.
DaeguAges 19 years+ - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07394257Recruiting
Antibiotic injection for hard-to-treat bacterial eye infection
This trial tests if an antibiotic injection directly into the cornea can help when standard eye drops are not working for a stubborn bacterial eye infection.
MinyaAges 20 years+ - NCT06830538Recruiting
Recovery and quality of life after corneal transplant
This study looks at how well people recover after a corneal transplant, including their vision, eye health, and overall quality of life. It aims to learn what helps people heal best after surgery.
BolognaAges 18 years+ - NCT07387159Recruiting
Studying MiYOSMART lenses to slow nearsightedness in kids
This trial tests whether special MiYOSMART iQ spectacle lenses can slow down worsening nearsightedness (myopia) in children. It aims to find a safe, non-invasive way to help kids see clearly longer.
MoscowAges 8–11 - NCT07388069Enrolling by invitationPhase 1/Phase 2
TN-001 eyedrops for progressive keratoconus
This trial tests a new eyedrop (TN-001) for people with keratoconus that is getting worse. The drops are applied twice a day to try to stop the cornea from thinning and bulging further.
Brisbane, QueenslandAges 18–40 - NCT07380256Recruiting
How vision affects balance and dizziness
This study looks at how vision problems and inner ear (vestibular) issues together affect balance. It aims to find better ways to help people with dizziness or balance problems.
Atlanta, GeorgiaAges 18–60 - NCT07381413Recruiting
Eye tracking study for thyroid eye disease
This study uses eye tracking to compare how people with thyroid eye disease move their eyes and pay attention to visual cues. It may help researchers understand eye movement problems better.
ShanghaiAges 18–70 - NCT07383701RecruitingPhase 2
Probiotic for diabetic macular edema
This trial tests whether a daily probiotic supplement (Lactiplantibacillus plantarum 299v) can help improve diabetic macular edema, a swelling in the back of the eye caused by diabetes. The goal is to see if adding this probiotic to your regular care could reduce swelling and protect your vision.
Boston, MassachusettsAges 18 years+ - NCT06425666Recruiting
Cataract surgery with triple-DMEK for Fuchs dystrophy
This trial tests a combined surgery that treats both cataract and Fuchs endothelial corneal dystrophy at the same time. It compares the standard cataract surgery to one that also replaces the damaged cornea layer, aiming to improve vision with fewer steps.
Aarhus N, Central JutlandAges 18 years+ - NCT06839898Recruiting
Study of two implantable astigmatism-correcting lenses
This study tests two types of implantable lenses that correct astigmatism (blurry vision from an irregularly shaped cornea). You keep your own natural lens, and the new lens is placed in front of it—no laser or lens removal needed. The goal is to see which lens works better and is safer.
Münster, North Rhine-WestphaliaAges 21 years+ - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07372911Recruiting
Comparing two cornea treatments for keratoconus
This trial tests two different laser-based procedures to treat keratoconus, a condition that weakens and bulges the cornea. The goal is to see which approach better strengthens the eye and improves vision.
Mexico City, Mexico CityAges 18 years+ - NCT07375940Recruiting
Understanding Behçet Disease in children and teens
This study looks at the health records and blood tests of children and young adults with Behçet disease to learn more about the condition. It also compares their results with healthy children to find clues that may help doctors better understand and treat Behçet disease.
Florence, FlorenceAges 6 months–70 years - NCT07376005Recruiting
How sugar affects eye thickness
This study looks at how a single sugary drink changes the thickness of a layer inside your eye (the choroid). It may help researchers understand how diet affects eye health.
Memphis, TennesseeAges 21–35 - NCT07378657RecruitingPhase 3
Sirolimus for children with orbital malformation
This trial tests if sirolimus can help children with a certain type of eye socket malformation. It aims to find a better treatment for children aged 1 to 18.
Cairo, Cairo GovernorateAges 1–18 - NCT07378891Enrolling by invitation
AI eye screening for early diabetic retinopathy
This study uses artificial intelligence (AI) to look at photos of the back of your eye (retina) to find early signs of diabetic eye disease. It aims to catch problems before they worsen, so you can get treatment sooner.
TübingenAges 18–80 - NCT07377513Recruiting
Can text reminders help corneal ulcer patients follow up?
This study tests if sending SMS reminders helps patients with corneal ulcers keep their follow-up appointments. It may help you stay on track with treatment and prevent complications.
Siddharthanagar, LumbiniAges 18–70 - NCT07373821Recruiting
Lying face up after cornea transplant surgery
This study tests if lying face up after DMEK surgery (a cornea transplant for Fuchs dystrophy) helps the surgery work better. It may be an option for people with Fuchs dystrophy or bullous keratopathy who can lie flat on their back.
HeidelbergAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.