Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05126147RecruitingPhase 4
Hydroxychloroquine for mild Graves’ eye swelling
This trial studies whether hydroxychloroquine can improve mild Graves’ orbitopathy (swelling and discomfort around the eyes). It’s meant for people with mild symptoms and who haven’t recently used certain eye or immune treatments.
HsinchuAges 18–75 - NCT05145361RecruitingEarly Phase 1
Study drug B001 for neuromyelitis optic spectrum disorder attacks
This early-phase study tests B001 injection to see if it can help people with neuromyelitis optica spectrum disorder (NMOSD) who have had recent relapses. It may be aimed at reducing future attacks and improving disability over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05147701RecruitingPhase 1
Testing stem cell treatment for NAION safety
This Phase 1 study tests whether lab-made stem cells taken from donated umbilical cord are safe for people with NAION. It mainly looks for side effects and safety rather than proving the treatment works.
St John'sAges Any age - NCT05150197Recruiting
Virtual reality eye test for children with eye disease
This trial studies whether a virtual reality (VR) eye test can measure a child’s vision field (where they can see) instead of standard testing. It may help clinics test children in a more comfortable way, especially if traditional tests are hard for kids.
Durham, North CarolinaAges 4–21 - NCT05153057Recruiting
Follow-up study for birdshot eye inflammation
This study follows people with “birdshot chorioretinopathy,” a rare eye inflammation, and collects immune (genetic) information to better understand the disease. You may benefit from closer monitoring, and the results may help guide future treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT05154370Recruiting
Registry for neuroinflammation diseases and diagnosis categories
This study is a registry that collects information from people diagnosed with certain neuroinflammation conditions. It may help doctors learn how these diseases behave over time and support future research.
Beijing, Beijing MunicipalityAges Any age - NCT05157113RecruitingPhase 4
After cataract surgery, a drop-free medicine plan
This trial studies whether a “drop-free” medication plan after cataract surgery works well and is practical for people receiving care at a county hospital. It may help reduce the need for multiple eye drops after surgery while still protecting the eye as it heals.
San Francisco, CaliforniaAges 18 years+ - NCT05163951Recruiting
Surgery comparison for advanced angle-closure glaucoma
This trial compares two types of glaucoma surgery—trabeculectomy versus a different procedure that also opens the drainage angle—for people with advanced primary angle-closure glaucoma. It aims to see which surgery controls eye pressure and preserves vision better.
Guangzhou, GuangdongAges 45–80 - NCT05191706RecruitingPhase 4
Check how safe DEXYCU is after childhood cataract surgery
This trial studies whether DEXYCU is safe to use to reduce eye inflammation after cataract surgery in children. It aims to see if the medicine’s side effects are acceptable and whether it helps during normal recovery.
Huntington Beach, CaliforniaAges Up to 3 years - NCT05199688RecruitingPhase 3
Satralizumab for children with AQP4-positive NMOSD attacks
This trial studies satralizumab in children ages 2 to 11 with a specific type of NMOSD caused by AQP4 antibodies. It aims to see how well the medicine prevents attacks and is safe over time.
Denver, ColoradoAges 2–11 - NCT05199896Recruiting
Brain and touch study for people with early blindness
This study looks at how the brain works when people who are blind (from birth or early childhood) touch and move. It uses an MRI brain scan to compare responses, aiming to better understand learning and brain processing in early visual loss.
BronAges 18–60 - NCT05200715Recruiting
Registry study for inherited and inflammatory eye and joint diseases
This study is a registry, meaning it collects your medical information to better understand several inflammatory (auto-inflammatory) conditions. It may help doctors and researchers improve diagnosis and future treatments for people with these disorders.
AlgiersAges Any age - NCT05204459Recruiting
MRI and eye-scan study for MS and related conditions
This trial uses brain MRI and eye imaging tests to study research markers in people with multiple sclerosis (MS) and related neurologic conditions. It may help researchers better understand these diseases and how they change over time.
Los Angeles, CaliforniaAges 18 years+ - NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT05264818Recruiting
Study measures eye surface sugar layer in glaucoma
This study looks at a thin “sugar coating” on the inside surface of the eye (the endothelial glycocalyx) in people with primary open-angle glaucoma and compares it with people without optic nerve disease. The results may help researchers better understand how glaucoma affects the eye.
ParisAges 18 years+ - NCT05275738Recruiting
Nicotinamide treatment for glaucoma progression
This trial studies whether nicotinamide (a form of vitamin B3/niacin) can slow or affect glaucoma progression. You may be eligible if you have newly diagnosed, untreated glaucoma or if you have treated glaucoma with measurable visual field changes.
StockholmAges 18 years+ - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT05314738RecruitingPhase 1/Phase 2
Corneal cross-linking trial for keratoconus eye
This trial tests how safe and effective corneal cross-linking is for people with keratoconus, a condition that changes the shape of the clear front surface of the eye. If you qualify, the study will also require several follow-up visits to check your eye health over time.
Dothan, AlabamaAges 18–55 - NCT05340647Recruiting
Study of micro-invasive glaucoma surgery options
This trial studies outcomes after certain minimally invasive glaucoma surgeries, including the Preserflo microshunt. It may help improve how safely and effectively glaucoma surgery is done, and how patients are followed afterward.
OsloAges 18 years+ - NCT05344274RecruitingPhase 4
Eye blood flow study in people with glaucoma
This study measures how blood flows in the retina and how well the eye regulates that flow. It compares people with early or very early glaucoma to people without glaucoma to see what differences may predict progression.
Baltimore, MarylandAges 18–88 - NCT05344651Recruiting
Compare two glaucoma drainage devices and cornea effects
This study compares two surgical drainage devices used for glaucoma and looks at how they affect the clear front window of the eye (the cornea). It may help you understand which device is gentler on the cornea over time.
RotterdamAges 18–100 - NCT05349006RecruitingPhase 3
Azathioprine for first attack in MOG antibody disease
This Phase 3 trial studies whether azathioprine can help prevent problems after a first attack of MOG antibody–related inflammation of the brain/spinal cord. It’s for adults with a recent first episode and confirmed MOG antibodies.
BordeauxAges 18 years+ - NCT05355415Recruiting
Eye imaging study for outer retina diseases using adaptive optics
This study uses a special, high-detail eye imaging machine to take clear pictures of the outer retina. It may help researchers understand these eye conditions better, and how the eye images look when people have an outer retinal disease.
Bethesda, MarylandAges 21 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.