Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07440225RecruitingPhase 2/Phase 3
Testing a new drug for wet macular degeneration
This trial tests a new medicine called EYE201/MK-8748 for people who have wet age-related macular degeneration (a condition where abnormal blood vessels grow under the retina). It's for those who haven't had treatment before and were diagnosed recently.
Scottsdale, ArizonaAges 50 years+ - NCT07440277Recruiting
Shunt vs. stent for IIH with vision loss risk
This study compares two treatments for Idiopathic Intracranial Hypertension (IIH) with severe papilledema (swollen optic nerves) and risk of vision loss: a CSF shunt (a tube to drain extra fluid) and a venous sinus stent (a mesh tube to open a narrowed vein). The goal is to see which works better and is more cost-effective.
BirminghamAges 18–63 - NCT07443683Recruiting
Eye health training for female health volunteers
This trial tests if teaching female community health volunteers about eye health can lead more people in their community to visit a vision center. It focuses on understanding how to improve access to eye care.
Dhangadi, SudurpaschimAges 18–58 - NCT07436247Recruiting
Measuring vision and eye shape after cataract surgery
This study tests new ways to measure how well your eye sees after having cataract surgery with a special lens that helps with reading and distance. They'll take detailed measurements of your eye to improve future lens designs.
ViennaAges 21–110 - NCT06810011Recruiting
Eye disease treatment study using medical records
This study uses a computer system to look at medical records of people who have had a certain type of eye injection. It aims to improve how information about eye treatments is shared and understood.
Chemnitz, SaxonyAges 18 years+ - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT06132035RecruitingPhase 1
CG-P5 eye drops for wet macular degeneration
This study tests a new eye drop (CG-P5) for people with wet age-related macular degeneration. It aims to see if the drops are safe and may help improve vision.
Manchester, ConnecticutAges 50 years+ - NCT07435142Recruiting
Urine-derived cells for corneal eye disease
This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.
Jinan, ShandongAges 18–85 - NCT07427160Recruiting
Study on best treatment for bleeding under the retina
This trial looks at whether the type of abnormal blood vessels under the retina affects how well a procedure (pneumatic displacement) works to move a macular hemorrhage (bleeding) out of the central vision area. It may help doctors choose the best approach for patients.
Trento, TrentoAges 50 years+ - NCT07434713Recruiting
Testing early response to Eylea 8mg for wet AMD
This study looks at how quickly fluid in the retina clears after starting treatment with a higher dose of Eylea (aflibercept 8mg) for wet age-related macular degeneration (AMD). It aims to understand if early fluid changes can predict long-term outcomes.
BernAges 50 years+ - NCT07428668Recruiting
Laser treatment for eye pressure changes in glaucoma
This trial tests a laser treatment called DSLT to see how it affects eye pressure changes over 6 months. It may help people with open-angle glaucoma or high eye pressure who are currently using 0 to 3 types of pressure-lowering eye drops.
Fort Worth, TexasAges 18 years+ - NCT07434635RecruitingPhase 4
Atropine for pain after vitrectomy surgery
This study tests whether atropine eye drops can reduce pain and prevent scar tissue (called posterior synechiae) after vitrectomy surgery. The goal is to see if this treatment helps you recover more comfortably.
San Francisco, CaliforniaAges 18 years+ - NCT07430735Recruiting
Moisture chamber glasses for dry eye relief
This trial tests a special pair of glasses that create a moisture chamber to relieve dry eye symptoms. It is for adults with mild to moderate dry eye who already wear glasses.
Rochester, New YorkAges 18 years+ - NCT06345898RecruitingEarly Phase 1
Gene therapy for X-linked retinoschisis in young males
This trial tests a single gene therapy injection under the retina for boys with X-linked retinoschisis, a condition that causes vision loss. It aims to see if the treatment is safe and can improve vision.
Chengdu, SichuanAges 5–18 - NCT07417566RecruitingPhase 1
DC6001 Tablet Study in Healthy Chinese Adults
This trial tests a new tablet called DC6001 in healthy volunteers. It helps find out how the body processes the drug and if it is safe. You may join if you are a healthy adult between 18 and 55 years old.
Beijing, Beijing MunicipalityAges 18–55 - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Peoria, ArizonaAges 18 years+ - NCT07419334RecruitingPhase 3
Study of a new drug for Stargardt disease
This trial tests a new drug, ALK-001, to see if it can slow down vision loss from Stargardt disease. It is for people who have a confirmed genetic diagnosis and are between 8 and 45 years old.
Phoenix, ArizonaAges 8–45 - NCT07425574Recruiting
Study on how Stargardt eye conditions progress in children and adults
This study observes how Stargardt disease and similar eye conditions change over time in children and adults. It aims to learn more about the disease progression to help develop future treatments.
Phoenix, ArizonaAges 6 years+ - NCT05523869RecruitingPhase 2
Eye injection medicine after repeat retinal detachment surgery
This Phase 2 trial tests an injection of topotecan into the eye after surgery for retinal detachment that keeps coming back due to scar tissue (proliferative vitreoretinopathy). It may help improve how the retina heals after difficult, repeat operations when vision is usually very guarded.
Toronto, OntarioAges 18 years+ - NCT07416864Recruiting
Making eye care services more efficient
This trial looks at ways to improve the flow of eye care services by studying how patients go through planned procedures. It may help find ways to make things smoother and faster for everyone.
Secunderabad, TelanganaAges Up to 85 years - NCT07425535RecruitingEarly Phase 1
Optic nerve strain study for people without glaucoma
This study looks at how the optic nerve (the part of your eye that sends images to your brain) strains or bends in people who do not have glaucoma. It uses advanced eye imaging and home pressure checks to understand the nerve's health.
Baltimore, MarylandAges 30–90 - NCT07424755Recruiting
AI eye test for cataract with high nearsightedness
This trial uses an artificial intelligence system to analyze detailed eye images from people who have both cataracts and severe nearsightedness (high myopia) with a specific eye shape (posterior staphyloma). The goal is to see if the AI can help doctors better understand and manage these conditions.
ShanghaiAges Any age - NCT07417046Recruiting
Fluoxetine and eye patching for lazy eye treatment
This study tests whether a combination of a medicine (fluoxetine) and eye patching can improve vision in people with lazy eye (amblyopia). It uses special eye scans and brain wave tests to see how well the treatment works for different ages.
Minya, Minya GovernorateAges 10 years+ - NCT07420296RecruitingPhase 3
Modified zipper therapy for AQP4-positive neuromyelitis optica
This trial tests a new treatment called modified zipper therapy for people with neuromyelitis optica spectrum disorder (NMOSD) who have a specific antibody (AQP4-IgG) in their blood. It aims to stop a recent attack and improve recovery.
TianjinAges 18–80
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.