Medical genetics
Genetic & congenital clinical trials
Inherited and congenital conditions present from birth or written into the genes. We’re tracking 3,858 recruiting studies in this area right now.
By phase
- Not applicable2,772
- Phase 2282
- Phase 1235
- Phase 3215
- Phase 1/Phase 2204
- Phase 497
- Phase 2/Phase 353
Top conditions
- Sickle Cell Disease140
- Atopic Dermatitis129
- Congenital Heart Disease86
- Cystic Fibrosis78
- Down Syndrome54
- Genetic Disease42
- Duchenne Muscular Dystrophy39
- Fabry Disease38
- Hemophilia A38
- Cystic Fibrosis (CF)37
- Cardiac Amyloidosis35
- Huntington Disease32
- Lynch Syndrome32
- Heart Failure31
- Retinitis Pigmentosa31
- Bronchopulmonary Dysplasia30
- Congenital Diaphragmatic Hernia29
- Duchenne Muscular Dystrophy (DMD)27
Leading sponsors
- Assistance Publique - Hôpitaux de Paris62
- Boston Children's Hospital42
- National Institute of Allergy and Infectious Diseases (NIAID)38
- Mayo Clinic37
- Children's Hospital Medical Center, Cincinnati33
- Hospices Civils de Lyon32
- IRCCS Azienda Ospedaliero-Universitaria di Bologna32
- Riphah International University26
- Massachusetts General Hospital23
- National Cancer Institute (NCI)23
Where studies are running
- California340
- Maryland161
- Alabama132
- Massachusetts116
- New York84
- Arizona79
- Texas73
- Minnesota67
- Pennsylvania65
- Ohio57
Recruiting studies3,858 total
- NCT07253038Recruiting
Testing social skills in Huntington's disease
This study tests three different ways to measure social skills (like understanding emotions or reading social cues) in people with Huntington's disease. The goal is to find which test works best for future research and care.
LundAges 18–75 - NCT07254000RecruitingPhase 2
Anakinra dosing study for preterm infants
This trial tests different doses and ways of giving a medicine called anakinra to preterm babies. It aims to find the safest and most effective dose to help reduce inflammation.
Clayton, VictoriaAges 6 months–7 months - NCT07255131Recruiting
Online talk therapy for cystic fibrosis
This study tests an online cognitive behavioral therapy (a type of talk therapy) program designed for people with cystic fibrosis. It aims to help improve mental health and coping skills through 13 video sessions.
AthensAges 18–70 - NCT07255144Recruiting
Ultrafast ultrasound imaging for children's heart conditions
This study tests a new, faster ultrasound technique to see heart structure and blood flow in children with or without congenital heart disease (CHD). It aims to improve imaging without risk, using a short scan during a regular check-up.
Pessac, FranceAges Any age - NCT07257185RecruitingPhase 3
MHB018A for Chronic Thyroid Eye Disease
This study tests a new medication called MHB018A for people with chronic Thyroid Eye Disease (TED) that is moderate to severe. It aims to see if the drug can help improve symptoms and quality of life over time.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07259343Recruiting
Cream with milk peptide for children's mild eczema
This trial tests if a special cream made with a milk protein peptide can improve mild eczema symptoms like itching and reduce bacteria on the skin in children aged 2 to 12.
Aguascalientes, AguascalientesAges 2–12 - NCT07260071Recruiting
High blood pressure in kids at risk for inherited kidney disease
This study looks for early signs of high blood pressure in children and teens (12–17) who have a parent with ADPKD, a kidney condition. It uses non-invasive tests like blood pressure monitoring and MRI to track kidney health.
LondonAges 12–17 - NCT07261891Recruiting
Lab study of JAK-STAT related disorders
This study looks at blood or tissue samples from people with certain genetic disorders that affect a key cell communication pathway (JAK-STAT). The goal is to learn more about these disorders and test potential treatments in the lab.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07262476RecruitingPhase 3
Extension study of MHB018A for thyroid eye disease
This study tests a longer-term use of MHB018A for people with thyroid eye disease who did not fully respond to treatment in a previous study. It aims to see if further treatment can help improve eye bulging and other symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07263490Recruiting
Pre-eclampsia Risk in Egg Recipients Study
This study looks at whether women who become pregnant after receiving donated eggs have a higher risk of developing pre-eclampsia (a serious blood pressure condition) during pregnancy. It aims to understand risks so doctors can better support pregnant women.
CopenhagenAges 18 years+ - NCT07263685Recruiting
Study of takhzyro (lanadelumab) for teens and adults with HAE in Saudi Arabia
This study looks at how well Takhzyro (lanadelumab) works for people with a specific type of hereditary angioedema (HAE) that is caused by a C1 inhibitor deficiency. It is for teenagers and adults who have already been taking Takhzyro for at least 6 months.
RiyadhAges 12 years+ - NCT07264036Recruiting
Nasal Speech After Head and Neck Cancer Treatment Study
This study is for people who have had treatment for head or neck cancer and now have a nasal-sounding voice. It tests a procedure to help improve speech by adding a small amount of filler material to the back of the throat.
Charlottesville, VirginiaAges 18 years+ - NCT07265388Recruiting
Testing a scoring system for Fuchs dystrophy and cataract surgery
This study tests a scoring system to predict how well people with Fuchs dystrophy do after cataract surgery. It may help doctors plan better treatment for your cornea and lens.
Madrid, MadridAges 40 years+ - NCT07266805RecruitingPhase 3
Oral deucrictibant for preventing and treating angioedema attacks in AAE-C1INH
This trial tests two forms of an oral medication to prevent and treat sudden swelling attacks in people with a rare condition called acquired angioedema due to C1 inhibitor deficiency. It aims to see if the drug can reduce attack frequency and manage acute episodes.
San Diego, CaliforniaAges 18 years+ - NCT07273643Recruiting
Studying tiny particles in cord blood of very premature babies
This study looks at microscopic particles called extracellular vesicles in the umbilical cord blood of babies born before 28 weeks. Researchers want to see if these particles can help predict severe health problems or death, and eventually improve care for extremely premature newborns.
MontpellierAges birth–3 months - NCT07273721RecruitingPhase 2
Testing BT200 in type 2B von Willebrand disease
This trial tests a new medicine called BT200 (rondaptivon pegol) to see if it can safely help people with type 2B von Willebrand disease who have low platelets and recent bleeding problems.
Vienna, State of ViennaAges 18 years+ - NCT07274631Recruiting
Study of inflammatory lung diseases
This study collects information from people with various inflammatory lung conditions, like asthma or COPD, to better understand them and improve treatment. Healthy volunteers are also needed for comparison.
ReimsAges 18 years+ - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT07276087Recruiting
Physical and Mental Health in Takayasu Arteritis and Behçet's Disease
This study compares physical and mental health in people with Takayasu arteritis or Behçet's disease to healthy volunteers. It aims to better understand how these conditions affect day-to-day life and well-being.
Denizli, DenizliAges 18 years+ - NCT07277361Recruiting
Quality of life study for Fabry disease patients aged 65+
This study looks at the quality of life of people aged 65 and older with Fabry disease. It includes patients who are receiving specific treatment and those who are not, to compare their experiences.
Paris, FranceAges 65 years+ - NCT07278843Recruiting
Understanding vision loss in Usher syndrome type 1B
This study follows people with Usher syndrome type 1B over time to learn how vision loss progresses. It also tests new ways to measure functional vision, which may help design future treatments.
Paris, Île-de-France RegionAges 3–75 - NCT07279883Recruiting
Nerve block for pain after cleft palate surgery in children
This study looks back at the medical records of children who had cleft palate surgery in 2017 or 2018. It compares how long they stayed in the hospital and their pain needs after surgery, between those who got standard pain medicine alone and those who also got a nerve block to help with pain.
StockholmAges 3 months–15 years - NCT07280104Recruiting
Infants with congenital hypothyroidism and development
This study looks at how babies with primary congenital hypothyroidism (low thyroid hormone from birth) grow and develop after being treated. It helps doctors understand if treatment helps them reach normal milestones.
NiğdeAges 6 months–1.5 years - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Little Rock, ArkansasAges 18 years+
Common questions
- How many genetic & congenital clinical trials are recruiting?
- Clin2 is tracking 3,858 recruiting medical genetics studies from the U.S. registry right now, out of 5,795 we cover in this area in total.
- What does “Genetic & congenital” cover here?
- Inherited and congenital conditions present from birth or written into the genes. We group each study into genetic & congenital based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a genetic & congenital trial near me?
- Use the search to filter genetic & congenital studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.