Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06928649Recruiting
Studying cell damage in critically ill ICU patients
This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.
EdegemAges 18 years+ - NCT06928675Recruiting
Cell-free DNA in acute stroke
This study looks at how a substance called cell-free DNA in the blood changes in people with a large blood clot causing a stroke. It aims to improve understanding of this condition and might help with future treatments.
BaselAges 18 years+ - NCT06929169RecruitingPhase 2
SGLT2 inhibitor heart health study in dialysis patients
This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug also used for heart failure) affects the heart and blood vessels in people with kidney failure who are on dialysis. It will help doctors understand if this medicine is safe and helpful for dialysis patients.
Buenos Aires, Buenos AiresAges 18–70 - NCT06930131Recruiting
Word-finding therapy with thinking skills training after stroke
This study tests a new talking therapy for people with word-finding problems after a stroke. It combines exercises to help you find words with training to think about how you learn and remember them.
ToulouseAges 18 years+ - NCT06930417Recruiting
Williams syndrome and related 7q11.23 changes study
This study follows people with Williams syndrome, 7q11.23 duplication, or related genetic changes over time to understand how these conditions affect health and development. It also includes close family members to learn about the genetics.
Philadelphia, PennsylvaniaAges Any age - NCT06930521Recruiting
Monitoring heart health during HER2 therapy for breast cancer
This study tracks how well the heart handles HER2-targeted therapy (like Herceptin) during the first year of treatment for early-stage breast cancer. It helps keep you safe by checking heart function closely.
Toronto, OntarioAges 18–79 - NCT06930638RecruitingPhase 2
MitoQ and leg conditioning for stroke recovery
This study tests whether a supplement called MitoQ and a special leg-pumping technique can improve blood vessel health in people who had a stroke at least 6 months ago. It may help your body recover better after a stroke.
Milwaukee, WisconsinAges 18–85 - NCT06930885RecruitingPhase 3
Polypill and colchicine for heart and artery risk
This trial tests a combination pill (polypill) and a medicine called colchicine to see if they can lower the risk of future heart attacks, strokes, or other artery problems. It is for people who already have a history of heart or blood vessel disease.
Maceió, AlabamaAges 45 years+ - NCT06931470Recruiting
Remote exercise training study for heart health
This study tests whether a remotely supervised exercise program is feasible and helpful for people who are at risk for heart disease but are not currently active enough. You would do exercises at home while being guided and monitored online.
New York, New YorkAges 45 years+ - NCT06931535Recruiting
Arm cuff treatment for recent moderate back-of-brain stroke
This trial tests whether a simple, non-drug treatment (using a blood pressure cuff to briefly restrict blood flow to your arm) can help people with a recent moderate stroke in the back part of the brain. It aims to improve recovery by preparing the body to better handle the stroke damage.
ShenyangAges 18 years+ - NCT06932029Recruiting
Home blood pressure monitoring for older adults
This trial tests if checking your blood pressure at home can help you and your doctor manage high blood pressure better, especially if you also have other health conditions. You will use a home monitor and share your readings with your care team.
Iowa City, IowaAges 65 years+ - NCT06932081Recruiting
Study of SGLT2i in adults with congenital heart disease
This trial is a registry that follows adults with congenital heart disease who have started taking an SGLT2 inhibitor medication. The goal is to learn how well this treatment works for this group of patients.
Baltimore, MarylandAges 18 years+ - NCT06932562RecruitingPhase 3
Testing linvoseltamab vs standard care for myeloma patients not eligible for transplant
This trial compares a new drug called linvoseltamab to standard treatments for multiple myeloma. It is for people who cannot have a stem cell transplant and have not had extensive prior therapy.
AdelaideAges 18 years+ - NCT06932874RecruitingPhase 4
Metformin for diabetes with heart disease
This trial tests a long-acting metformin pill in people with both type 2 diabetes and coronary heart disease. It aims to see if metformin can safely help control blood sugar in this specific group.
Beijing, Beijing MunicipalityAges 30–75 - NCT06933212Recruiting
Mediterranean diet for CADASIL and CAA
This trial is testing whether a Mediterranean diet (rich in fruits, vegetables, whole grains, and healthy fats) can help people with CADASIL or cerebral amyloid angiopathy (CAA) — two conditions that affect blood vessels in the brain. If you have one of these diagnoses, the study may help you understand how diet can support your brain health.
MilanAges 18 years+ - NCT06933277Recruiting
Study of selinexor, bortezomib, and dexamethasone for multiple myeloma
This observational study looks at a three-drug combination (selinexor, bortezomib, and dexamethasone) for people with multiple myeloma that has come back after 1 to 3 prior treatments. It may be an option if you've already tried and not responded to lenalidomide.
FlorenceAges 18 years+ - NCT06934798RecruitingPhase 4
Vasopressin vs. Noradrenaline for low blood pressure after heart surgery
This trial compares two medications, vasopressin and noradrenaline, to see which one works better at raising blood pressure in patients who develop dangerously low blood pressure (vasoplegic syndrome) within the first day after heart surgery. The goal is to find the safest and most effective treatment to stabilize blood pressure and help recovery.
São PauloAges 18 years+ - NCT06935253Recruiting
AI to Improve Cardiology Care
This trial tests whether large language models (a type of AI that understands human language) can help cardiologists give better care. If you are a qualified cardiologist who currently treats patients, you may be eligible.
Palo Alto, CaliforniaAges 18 years+ - NCT06935513Recruiting
Wearable devices for stroke prevention
This trial tests if using a smart wearable device can help people at high risk for stroke stay active and reduce their risk. You may be able to join if you have certain health conditions or habits that increase your stroke risk.
Nantong, JiangsuAges 30 years+ - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Jonesboro, ArkansasAges 22 years+ - NCT06935786Recruiting
Sedentary lifestyle and health risks in kidney disease
This study looks at how a sedentary (mostly sitting or lying down) lifestyle affects people with advanced chronic kidney disease. It aims to see if being less active is linked to higher risks of death or major health problems.
PoriAges 40 years+ - NCT06936111Recruiting
Can extra cholesterol-lowering help after a stent?
This trial looks at whether stronger cholesterol-lowering medicine can reduce the risk of future heart problems in people who already have a stent. It focuses on people who still have other mildly narrowed spots in their arteries.
ShanghaiAges 18–75 - NCT06936176Recruiting
Studying a new balloon procedure for calcified carotid artery disease
This trial tests a special balloon (IVL) to treat hardened plaque in the neck arteries that supply blood to the brain. It is for people who need a stent but whose previous balloon treatment did not work well.
BeijingAges 18–80 - NCT06936189Recruiting
Extended follow-up study of IVL for carotid artery disease
This trial is collecting long-term safety and effectiveness data from patients who already completed a study of a device called IVL (shockwave therapy) for calcium buildup in the carotid artery. It does not require any new treatments or tests.
BeijingAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.