Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT06838416Recruiting
Study on finerenone for kidney health in type 2 diabetes
This trial tests if a medicine called finerenone can protect kidney function in people with type 2 diabetes and early-to-moderate chronic kidney disease. It may be an option if you are already on blood pressure medication and have some protein in your urine.
Suzhou, JiangsuAges 18 years+ - NCT07224893RecruitingPhase 4
Once vs Twice Daily Insulin in Pregnant Diabetes
This trial compares taking insulin glargine once a day versus twice a day for pregnant women with type 2 diabetes. It aims to find which schedule helps manage blood sugar better during pregnancy.
Norfolk, VirginiaAges 18 years+ - NCT07224334RecruitingPhase 1
How cells talk to adjust insulin for weight
This study looks at how cells in the pancreas communicate to help the body produce enough insulin when you have insulin resistance (weight-related). It tests a peptide to see how this communication works.
Durham, North CarolinaAges 18–60 - NCT07226128Recruiting
Can therapy help HIV patients with depression and insulin resistance?
This study tests if cognitive behavioral therapy (a type of talk therapy) can improve how your body handles sugar (insulin resistance) for people living with HIV who also have depression. You may join if you have HIV, are on stable HIV meds, feel depressed, and do not have diabetes.
Indianapolis, IndianaAges 18 years+ - NCT07223242RecruitingPhase 2/Phase 3
Tailored exercise training for heart failure with preserved pumping strength
This trial tests a personalized exercise program to help people with a type of heart failure called HFpEF. You may qualify if your heart still pumps well but you have trouble being active, and you are willing to use a phone app and exercise regularly.
Dallas, TexasAges 18 years+ - NCT07229014Recruiting
Collagen supplement for quality of life and appetite
This trial tests whether a daily collagen supplement can improve quality of life, appetite, and blood sugar control in overweight adults who feel low energy or have trouble sleeping. You will take the supplement, use a continuous glucose monitor, and complete online surveys.
London, LondonAges 18–65 - NCT07226804Recruiting
Pulsed field ablation for benign thyroid nodules
This trial tests a new procedure called nanosecond pulsed field ablation (nsPFA) to shrink benign thyroid nodules that are causing symptoms like tightness in the throat or trouble swallowing.
Houston, TexasAges 18 years+ - NCT07224438RecruitingPhase 2
Kisspeptin injections for menopause-like condition from stress or diet
This trial tests if kisspeptin injections can help women with hypothalamic amenorrhea (a pause in periods due to stress, low weight, or too much exercise). The goal is to see if it can restart the reproductive system naturally.
Boston, MassachusettsAges 18–45 - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07229963Recruiting
Short exercise breaks for improving after-meal health in overweight adults
This study looks at how different ways of breaking up long periods of sitting (like short exercise breaks) affect your body after meals, especially in overweight adults. It may help you learn simple strategies to improve how your body handles food and sugar.
Ankara, BeytepeAges 30–45 - NCT07227051Recruiting
Phone app and fitness tracker for weight loss study
This study tests a smartphone app and fitness tracker to help people lose weight by monitoring their diet and activity. Participants get feedback and support through the app.
Milwaukee, WisconsinAges 18 years+ - NCT07229170Recruiting
Taste changes and eating habits on weight loss drugs
This study looks at how GLP-1 medications (like semaglutide/Wegovy or tirzepatide/Mounjaro) change your sense of taste and eating habits while losing weight. If you are 18–60, have obesity, and have been taking one of these drugs for at least 12 weeks, you may qualify.
Roma, ItalyAges 18–60 - NCT07223268Recruiting
Support program for diabetic foot problems
This study tests a program that provides extra help and resources to people with diabetes who have a foot ulcer or a toe amputation. The goal is to see if this support helps them manage their condition and avoid future problems.
Atlanta, GeorgiaAges 18 years+ - NCT07225153Recruiting
Goat milk formula vs. undiluted goat milk for infant growth
This trial tests whether a goat milk-based formula helps infants who cannot breastfeed grow as well as those who drink undiluted goat milk. It focuses on babies living in the Matiari District whose families have access to goat milk.
Matiāri, SindhAges 2 months–2 months - NCT07223151Recruiting
A taste test to help teens drink fewer sugary sodas
This study tests whether a special way of tasting sweet drinks can help teens who love sugary beverages cut back on them. It might help you reduce sugar and improve your health.
Bloomington, IndianaAges 12–18 - NCT07228429Recruiting
Measuring calcium deposits in scleroderma with CT scans
This study will use CT scans to measure calcium deposits under the skin in people with scleroderma. It may help doctors better understand and track this condition.
New Haven, ConnecticutAges 18 years+ - NCT07226947Recruiting
Exercise to prevent muscle loss with GLP-1 medication
This study looks at whether exercise can help prevent muscle loss in people taking GLP-1 medications (like Wegovy, Ozempic, or Mounjaro) for weight loss. It may help you keep your muscles strong while you lose weight.
Boston, MassachusettsAges 18–99 - NCT07229482Recruiting
Potatoes and your health: a 14-week food study
This study tests whether eating potatoes (as part of a provided diet) can improve blood sugar and heart health markers – possibly lowering your risk for type 2 diabetes.
Blacksburg, VirginiaAges 50–70 - NCT07225309Recruiting
Meaning-Centered Therapy for Mexican Adults with Advanced Cancer
This study tests a therapy program called Meaning-Centered Therapy designed to help adults in Mexico with advanced cancer find meaning and improve their well-being. It involves sessions delivered by trained providers at the National Cancer Institute in Mexico (INCan).
New York, New YorkAges 18 years+ - NCT07228741RecruitingPhase 2
Exercise and medicine for heart health in ALL survivors with obesity
This trial tests if combining resistance exercise with the weight-loss medication tirzepatide can improve heart and metabolic health in survivors of childhood acute lymphoblastic leukemia (ALL) who are now adults and have obesity or overweight with related health issues. You may benefit if you finished treatment at least 2 years ago and meet weight and health criteria.
Memphis, TennesseeAges 18 years+ - NCT07229768RecruitingEarly Phase 1
Study of 177Lu-CTR-FAPI for advanced solid tumors
This trial tests a radioactive drug called 177Lu-CTR-FAPI for people with advanced solid tumors that have not responded to standard treatments. It targets tumors that show a specific protein (FAP) on PET scans. The study focuses on certain cancers like pancreatic, breast, and soft tissue sarcoma.
ShanghaiAges 18–85 - NCT07229508Recruiting
Weight gain study for children from BIPOC or low-income families
This study looks at how children gain weight over time, especially in families of color or with low income. It helps understand why some kids struggle with weight and what can be done to help.
Buffalo, New YorkAges 8–11 - NCT07228130Recruiting
A weight loss study using a smartphone app
This study tests a smartphone app to help with weight loss by tracking habits. It may be a good fit if you are ready to try a new approach to managing your weight.
Providence, Rhode IslandAges 18–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.