Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06748365Recruiting
Ferritin levels and recovery in diabetic ketoacidosis
This study looks at whether the level of a protein called ferritin in your blood can help predict how well you recover from diabetic ketoacidosis (DKA). If you have DKA and are over 18, you may be able to join.
Sohag, Sohag GovernorateAges 18 years+ - NCT06970626RecruitingPhase 2/Phase 3
Comparing pain relief methods after sleeve gastrectomy
This study compares two ways to manage pain after laparoscopic sleeve gastrectomy: one uses a medication called dexmedetomidine given through an IV, and the other uses a combination of nerve blocks (TAP block and paragastric block) to see which leads to a better recovery.
AlexandriaAges 20–60 - NCT06971380RecruitingPhase 2
CAR-T therapy for multiple myeloma and amyloidosis
This trial tests a new CAR-T cell treatment (HBI0101) for people with multiple myeloma or light-chain amyloidosis that has come back or stopped responding to other treatments. The therapy uses your own immune cells to fight cancer, and the goal is to see if it can help control the disease.
JerusalemAges 18 years+ - NCT06971159Recruiting
Vibration therapy and osteopathic care for obesity
This study tests whether gentle whole-body vibration therapy and osteopathic manual treatment (hands-on adjustments) can help people with obesity. It aims to see if these treatments improve weight-related health and well-being.
Rio de Janeiro, Rio de JaneiroAges 18–65 - NCT04151472RecruitingPhase 3
Idebenone to prevent episodic migraine attacks
This trial tests idebenone, a preventive medicine, to see if it can reduce how often migraine attacks happen. It mainly focuses on people with episodic migraine who have regular attacks and are not already using other migraine prevention treatments.
Hangzhou, ZhejiangAges 18–65 - NCT05352958Recruiting
Ultrasound checks breathing muscle function in ALS
This study uses a quick ultrasound test to check how well the breathing muscle (the diaphragm) works in people with amyotrophic lateral sclerosis (ALS). It may help doctors monitor breathing changes over time and guide care.
DijonAges 18 years+ - NCT06028503Recruiting
Diabetes self-management help for rural adults
This study tests a program to help people with type 2 diabetes living in rural areas better manage their condition. It uses a smartphone app and coaching to improve blood sugar control.
Conroe, TexasAges 18 years+ - NCT07094776Enrolling by invitation
MG53 protein levels in women with PCOS
This study measures a protein called MG53 in the blood of women with and without PCOS to see if it could be a marker for the condition. If you have PCOS and are not taking certain medications, you may be able to join and help researchers better understand the disease.
Gaziosmanpaşa, IstanbulAges 18–45 - NCT06363253Recruiting
Gut bacteria study in obesity and muscle loss
This study looks at the bacteria in your gut (the microbiome) to understand how they relate to obesity and muscle loss. Researchers will collect stool samples to analyze the gut bacteria, which may help find new ways to treat metabolic diseases.
SingaporeAges 21–99 - NCT07093476RecruitingPhase 3
Adding empagliflozin to improve blood sugar control
This trial tests whether adding empagliflozin (a diabetes pill) to your current medicines (alogliptin and metformin) helps manage blood sugar better. It may be an option if your blood sugar is not well controlled with your current treatment.
SeoulAges 19 years+ - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Scottsdale, ArizonaAges 1–25 - NCT07092618RecruitingPhase 2/Phase 3
Trial for keeping weight off after stopping GLP-1 meds
This study tests if other medicines (naltrexone, metformin, or rapamycin) can help people keep off weight they lost while taking GLP-1 drugs like Wegovy or Ozempic, after they stop taking them. It is for AgelessRx patients aged 40 to 85 who have lost at least 15 pounds on GLP-1s.
Chicago, IllinoisAges 40–85 - NCT07089875RecruitingPhase 3
Testing dotinurad vs allopurinol for people with gout
This study compares a new gout medicine called dotinurad to the common medicine allopurinol. It is for people who have had gout for at least a year, have had at least 2 gout attacks in the last year, and are already taking a stable dose of allopurinol but still have high uric acid levels.
Birmingham, AlabamaAges 18–75 - NCT07090499RecruitingPhase 1
Study of PF-08046876 for advanced solid tumors
This trial tests a new medicine, PF-08046876, for people with advanced cancers of the bladder, lung, head and neck, esophagus, or pancreas. It aims to see if the drug is safe and works against these cancers.
Duarte, CaliforniaAges 18 years+ - NCT07087808Recruiting
Family health program for teens with obesity in rural areas
This trial tests a virtual family intervention to help teens ages 12-17 with obesity and their primary caregiver (who is also overweight) improve health habits together. It's designed for families living in rural communities who both have a smartphone.
Charleston, South CarolinaAges 12–17 - NCT07086443RecruitingPhase 4
Testing a new wound therapy for diabetic foot ulcers
This study tests a new wound therapy for diabetic foot ulcers that haven't healed with standard care. It aims to see if the therapy helps these ulcers heal better and faster.
Monroeville, PennsylvaniaAges 18 years+ - NCT07089602RecruitingPhase 4
Placental membrane for diabetic and venous leg ulcers
This trial tests if a placental membrane product, when added to standard wound care, helps heal diabetic foot ulcers and venous leg ulcers faster than standard care alone.
Philidelphia, PennsylvaniaAges 18 years+ - NCT06973824Recruiting
20 years of pituitary tumor care
This study looks back at people who had surgery for pituitary tumors over the last 20 years. It aims to understand long-term outcomes and help improve future care.
Rome, ITAges 18 years+ - NCT07092228Recruiting
Virtual reality and plyometrics for teen girls with PCOS
This trial tests whether combining virtual reality with jump-training (plyometrics) helps teenage girls with PCOS improve their exercise ability. It aims to find a fun and effective way to get active.
IsmailiaAges 13–18 - NCT07094529Recruiting
Tailored low blood sugar treatment for type 2 diabetes
This study tests a personalized approach to treating low blood sugar (hypoglycemia) in adults with type 2 diabetes. It aims to find out if this tailored treatment plan is practical and helpful for people who take certain diabetes medications (sulfonylureas or insulin).
Ottawa, OntarioAges 18 years+ - NCT07087561Recruiting
Nutrition and health education after colorectal cancer surgery
This trial tests whether a short-term nutritional supplement combined with health education can improve recovery after surgery for colorectal cancer. It is for people with stage IIa, IIb, or IIIa colon or rectal cancer who have completed surgery and are able to engage in follow-up.
Xi'an, ShaanxiAges 18 years+ - NCT07095517RecruitingPhase 1
Preventing early-onset colorectal tumors with tirzepatide
This study tests if tirzepatide can help prevent early-onset colorectal tumors in people aged 18-50 who have had certain types of polyps removed. It aims to find risk factors and ways to stop colorectal cancer before it starts.
Boston, MassachusettsAges 18–50 - NCT07095543Recruiting
Plant-based weight loss through online program
This study tests an online weight loss program based on a plant-based diet. You may be able to join if you live in the U.S., are overweight, can travel to Washington DC for a body scan, and are not using weight loss medications.
Washington D.C., District of ColumbiaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.