Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT03699228Recruiting
Low-dose chest CT study for adults in China
This study is looking at people ages 30 to 90 who are willing to get a low-dose chest CT scan. It may help researchers improve how health data is collected and understood from scans.
Wuhu, AnhuiAges 30–90 - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Palo Alto, CaliforniaAges 30–70 - NCT06664866Enrolling by invitation
AI Screening for Heart Amyloidosis
This trial tests an AI program that looks at your heart ultrasound (echocardiogram) to find possible signs of cardiac amyloidosis early. It helps doctors decide if more testing is needed.
Los Angeles, CaliforniaAges 22 years+ - NCT06666933Enrolling by invitation
Time-restricted eating for PCOS with glucose issues during IVF
This study tests whether a time-restricted eating plan (eating only during certain hours of the day) can improve pregnancy rates in women with PCOS and glucose metabolism problems who are undergoing IVF. The goal is to see if this eating pattern helps your body respond better to treatment.
Shanghai, Shanghai MunicipalityAges 20–38 - NCT06666257Recruiting
Glucose monitoring for healthy weight during pregnancy
This study tests whether using a continuous glucose monitor and electronic tracking during pregnancy can help you maintain a healthy weight and prevent complications. It is designed for women who are early in pregnancy and have a higher BMI.
Little Rock, ArkansasAges 18–45 - NCT06665945Recruiting
SENTRY study: using blood platelets to detect ovarian cancer
This study looks at changes in blood platelets to see if they can help detect ovarian cancer earlier. It is for women who have a new ovarian or pelvic mass and are about to have a biopsy or surgery.
Salt Lake City, UtahAges 21 years+ - NCT06660888Enrolling by invitation
Study of fatigue, depression, and anxiety in people with low thyroid
This study looks at how common fatigue, depression, and anxiety are in people with hypothyroidism (underactive thyroid). It aims to understand if these symptoms are linked to thyroid hormone levels.
Asyut, AssuitAges 18–60 - NCT06669000Recruiting
How long to dissolve gout crystals
This study looks at how long it takes for urate crystals (the cause of gout) to dissolve in the body. It may help if you have gout, are not on uric acid-lowering medicine, and have higher uric acid levels.
ParisAges 18 years+ - NCT06661538RecruitingPhase 2
Food referrals to help children with health conditions
This study tests a program that helps families with food insecurity get connected to food resources. It is for children ages 5–18 who are already seen at certain specialty clinics and who receive Medicaid or SNAP.
La Jolla, CaliforniaAges 5 years+ - NCT06663072RecruitingPhase 1
Testing fulvestrant plus lutetium therapy for advanced pancreatic neuroendocrine tumors
This trial tests a new combination of two drugs: lutetium-177 DOTATATE (a type of radiation therapy that targets tumor cells) and fulvestrant (a hormonal therapy). It is for people with advanced pancreatic neuroendocrine tumors that have grown despite previous treatments.
Chicago, IllinoisAges 18 years+ - NCT06662006RecruitingPhase 2
Nal-IRI chemo with immunotherapy and radiation for pancreatic cancer
This trial tests a combination of chemotherapy (Nal-IRI, 5-FU, leucovorin), an immunotherapy drug (PD-L1 inhibitor), and a targeted anti-angiogenic pill, with or without radiation (SBRT), as a second-line treatment for people with metastatic pancreatic cancer that has progressed after first-line therapy.
Nanjing, JiangsuAges 18–75 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT06658067Recruiting
Study on continuous glucose monitors for type 2 diabetes
This study gives continuous glucose monitors (CGMs) to people with type 2 diabetes who cannot afford them. It looks at whether using a CGM helps improve blood sugar control.
New Haven, ConnecticutAges 18 years+ - NCT05332301Recruiting
Study of how men and women process a high-fat meal
This study looks at how the body’s metabolism changes after eating a high-fat meal, comparing differences between sexes. If you meet the health, diet, and medication rules, you may be asked to fast and have blood tests before and after the meal.
Hamilton, OntarioAges 18–35 - NCT06374368Recruiting
Small bowel diversion surgery for obesity
This trial tests a surgery called small bowel diversion to help people with obesity lose weight. It may also improve blood sugar control for those with type 2 diabetes.
OstravaAges 18–65 - NCT06647745RecruitingPhase 3
Study for type 2 diabetes and high blood pressure
This study tests a new combination of three medications (THP-00101, THP-00102, and THP-00103) for people with type 2 diabetes and essential high blood pressure. It aims to see if this combination is safe and effective compared to standard treatments.
SeoulAges 19 years+ - NCT06649955Recruiting
Controlling nerve activity in ALS with brain stimulation
This study tests a non-invasive brain stimulation technique (called transcutaneous spinal direct current stimulation and transcranial magnetic stimulation) to see if it can calm overactive nerves in people with ALS. You may be a good fit if you have ALS that started less than 3 years ago and your breathing is still strong.
Boston, MassachusettsAges 18–80 - NCT06645808RecruitingEarly Phase 1
PET imaging study for various solid tumors
This study uses a special PET scan to see if a new imaging agent can help find and monitor certain solid tumors. It is for people with colon, rectal, sarcoma, breast, lung, head and neck, esophageal, stomach, pancreas, bladder cancers, or glioblastoma who have had standard treatment before surgery.
Groningen, Provincie GroningenAges 18 years+ - NCT06651983Recruiting
Inflammation and complications in type 2 diabetes
This study looks at how inflammation relates to complications in people with type 2 diabetes. It is an observational study, meaning you don't receive any treatment — the goal is to understand the connection better.
Guangzhou, GuangdongAges 20 years+ - NCT06649071Enrolling by invitation
Obesity classification and brain imaging study
This study looks at how obesity is classified and what brain imaging can show in people with obesity. It may help researchers understand different types of obesity and how they affect the brain.
Nanjing, JiangsuAges 20–65 - NCT06648174Recruiting
Managing heart health risk after gestational diabetes
This study tests a program to help women who had gestational diabetes reduce their future risk of heart disease and diabetes. It checks if monitoring and support can improve health after pregnancy.
HsinchuAges 18 years+ - NCT06646107Recruiting
Mediterranean diet and insulin pump in type 1 diabetes
This trial tests whether following a Mediterranean diet can improve blood sugar control and insulin use in people with type 1 diabetes who are starting a new insulin pump (MiniMed 780G). It compares how diet affects glucose levels and insulin needs.
ChaïdáriAges 12–80 - NCT06656702RecruitingEarly Phase 1
Psilocybin for depression in amyotrophic lateral sclerosis
This trial tests whether psilocybin, a psychedelic drug, can safely help with depression in people with ALS. It also looks at how the drug affects your symptoms and quality of life over six months.
Baltimore, MarylandAges 18 years+ - NCT06649084Enrolling by invitation
Language treatment study for primary progressive aphasia
This study tests a multi-component language treatment for people with primary progressive aphasia (a type of dementia that first affects language). It aims to help improve communication skills with support from a study partner.
Austin, TexasAges Any age
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.