Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06673017RecruitingPhase 1
Testing a new treatment for pancreatic cancer before surgery
This trial tests a new treatment, PTM-101, placed during a laparoscopy procedure for people with pancreatic cancer that can be removed with surgery. It aims to see if adding this treatment before standard chemotherapy helps improve outcomes.
Newport Beach, CaliforniaAges 18 years+ - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06679270RecruitingPhase 3
Long-term safety study of metreleptin for partial lipodystrophy
This study tests the long-term safety of metreleptin for people with partial lipodystrophy. It is for those who already completed a related study and want to continue treatment.
Birmingham, AlabamaAges 13 years+ - NCT06675903Recruiting
Continuous Glucose Monitoring After Kidney Transplant
This study tests a small sensor called a continuous glucose monitor (CGM) that tracks your blood sugar after kidney transplant. It helps doctors see how your body handles sugar during recovery.
Copenhagen, DKAges 18 years+ - NCT06674109RecruitingPhase 4
Testing a diabetes drug for gout prevention
This study tests if a type 2 diabetes medication (SGLT2 inhibitor) can help people with frequent gout flares. It aims to lower uric acid levels and reduce flare-ups.
Boston, MassachusettsAges 18–80 - NCT06678685RecruitingPhase 2/Phase 3
Spironolactone for children with NCOR gene changes and autism
This trial tests if spironolactone can help children with autism who have a certain genetic change (in the NCOR gene). The study will monitor improvement and safety over time.
Jinan, ShandongAges 3–10 - NCT06676566Enrolling by invitation
Follow-up and early detection for kids at risk of type 1 diabetes
This study follows children who are at genetic risk for type 1 diabetes or have early immune signs (autoantibodies) but do not yet need insulin. It provides extra checkups and information to catch the disease early and help families understand their child's risk.
MalmöAges birth–18 years - NCT06672822RecruitingPhase 2
STS injections for calcinosis in scleroderma
This trial tests if injecting a medication called STS directly into calcium deposits can relieve pain and symptoms. It may help patients with scleroderma or related conditions who have painful calcium lumps.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06673329RecruitingPhase 1
Brodalumab for immune-related side effects from cancer treatment
This trial tests if brodalumab, an antibody that blocks a specific immune pathway (IL-17), can help control side effects caused by immunotherapy cancer treatment. It is for people with advanced solid organ cancers who have immune-related side effects that are suspected to involve IL-17.
New York, New YorkAges 18 years+ - NCT06669949Recruiting
Studying the natural history of SPLIS disease
This study collects health information from people with SPLIS to better understand the condition over time. It may include your siblings if they also have SPLIS, and data from patients who have passed away.
San Francisco, CaliforniaAges Any age - NCT06676878Enrolling by invitation
Body and fitness in boys with type 1 diabetes vs. healthy soccer players
This study looks at how soccer training affects the body, fitness, and temperature control in young boys with type 1 diabetes compared to healthy boys. It may help understand how exercise and diabetes interact.
Poznan, WlkpAges 15–17 - NCT06670625Recruiting
Diet and activity counseling for infants at risk for type 1 diabetes
This study tests whether a program of diet and activity advice for families can lower the risk of type 1 diabetes in infants who have a higher genetic chance of developing it. It aims to find simple, everyday ways to help protect your child.
MalmöAges 3 months–4 months - NCT06681246Recruiting
How gut bacteria affect weight regain after weight loss
This study looks at how the natural bacteria in your gut (the microbiome) might be linked to regaining weight after losing it. It tests whether a short course of antibiotics or a placebo (a sugar pill) affects this process. The goal is to find new ways to help people keep weight off long-term.
RehovotAges 18–65 - NCT06669715Recruiting
Physical fitness and heart health in adults
This study looks at physical fitness and blood flow in a wide range of adults. It aims to understand how fitness affects heart health across different people.
LjubljanaAges 18 years+ - NCT06677190RecruitingPhase 2
Belzutifan for Recurrent Clear Cell Gynecologic Cancer
This study tests a daily pill called belzutifan for people with a rare type of gynecologic cancer (clear cell carcinoma) that has come back or not gone away after standard treatments. The drug works by targeting a protein that helps tumors grow when oxygen levels are low.
Boston, MassachusettsAges 18 years+ - NCT06671184Recruiting
Predicting difficult thyroid surgery for less scarring
This trial looks at a tool doctors can use to predict if a certain type of thyroid surgery (through the mouth or under the chin) will be challenging. It helps people who want less visible scarring after their thyroid cancer surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT06677554RecruitingPhase 3
Using contrast ultrasound to diagnose ovarian torsion
This trial tests if a special ultrasound with contrast dye can better diagnose ovarian torsion (twisted ovary). It may help women get faster, more accurate treatment.
BesançonAges 18 years+ - NCT06661655Recruiting
Testing a new ultrasound for liver fat in MASLD patients
This study tests a new ultrasound device that uses sound waves to measure fat in the liver without needles or surgery. It is for people with a type of fatty liver disease called MASLD or MASH, who are already getting an MRI to check their liver.
AngersAges 18–80 - NCT06657859Enrolling by invitationPhase 2
Extended study of GLM101 for PMM2-CDG patients
This study is for people who already completed a previous trial of GLM101 for PMM2-CDG. It offers continued access to the treatment while doctors monitor safety and effects.
Minneapolis, MinnesotaAges 2 years+ - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06666413RecruitingPhase 4
Study of Nexviazyme in children with infantile Pompe disease
This study tests the safety and effects of the enzyme replacement therapy avalglucosidase alfa (Nexviazyme) in children with infantile-onset Pompe disease. It is for children who have had Pompe symptoms since infancy and heart problems at diagnosis.
ShanghaiAges Up to 17 years - NCT06665165RecruitingPhase 1
Study of AMX0114 for people with ALS
This study tests an experimental drug called AMX0114 for people recently diagnosed with ALS. It is an early-phase trial to see if the drug is safe and how it affects the body.
La Jolla, CaliforniaAges 18 years+ - NCT06663358Recruiting
Safety and effectiveness of Elfabrio in Fabry disease patients
This study is for people with Fabry disease who are taking or planning to take the medication Elfabrio (pegunigalsidase alfa). It will look at how safe and effective the treatment is in real-world use.
Birmingham, AlabamaAges 18 years+ - NCT03461237Recruiting
Study of care after osteoporotic hip fractures
This study looks at people with osteoporotic hip fractures (breaks in the femur near the hip) and evaluates their care and outcomes. It may help improve how hip fractures are treated in people whose bones are weaker due to osteoporosis.
Beijing, Beijing MunicipalityAges 50–95
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.