Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06648096RecruitingPhase 1/Phase 2
Testing afatinib for head and neck cancer in Fanconi anemia patients
This trial tests whether the targeted drug afatinib can shrink advanced head and neck cancers in people who also have Fanconi anemia. It is for patients whose tumors cannot be surgically removed and have not responded to or cannot have other standard treatments.
HanoverAges 18 years+ - NCT06645847Recruiting
Ketone drink for walking and strength in older adults
This study tests whether a special ketone drink can help older adults who are starting to feel frail (slower walking, less energy). You would be assigned to one of several groups, and researchers will check if the drink improves your strength and daily function.
Novato, CaliforniaAges 65 years+ - NCT06648434RecruitingPhase 1
MK2 inhibitor plus mFOLFIRINOX for metastatic pancreatic cancer
This trial tests an experimental drug called zunsemetinib (an MK2 inhibitor) combined with a standard chemotherapy regimen (mFOLFIRINOX) for people with pancreatic cancer that has spread to other organs. The goal is to see if the combination works better than chemotherapy alone.
St Louis, MissouriAges 18 years+ - NCT06655116Enrolling by invitation
Diabetes foot education study
This trial tests a structured education program for people with type 2 diabetes to help prevent foot problems. It's for those who haven't had formal foot training before.
Kayseri, TalasAges 18 years+ - NCT06651580Recruiting
Gene study for kids with pancreas problems
This study collects samples like blood or tissue from children with pancreatitis to look for gene changes that might raise their risk. It helps doctors learn more about why some children get pancreas inflammation.
Los Angeles, CaliforniaAges Up to 17 years - NCT06654336RecruitingPhase 2
Targeted therapy with or without hormone therapy for prostate cancer that has spread a little
This trial tests whether targeting the spots where cancer has returned with radiation or surgery, with or without hormone therapy, can help control prostate cancer that has come back in a few places after previous treatment.
Hamilton, OntarioAges 18 years+ - NCT06650319RecruitingEarly Phase 1
Testing LY-M003 injection for Wilson disease
This study tests an injection called LY-M003 for people with Wilson disease who have already been treated with standard medicines. The goal is to see if it is safe and works for them.
Hangzhou, ZhejiangAges 10–60 - NCT06645431Enrolling by invitation
Low water intake and blood sugar study
This study looks at how drinking less water affects your blood sugar levels throughout the day. Researchers will use a small monitor to track your glucose continuously to see if staying hydrated matters for healthy blood sugar control.
San Luis Obispo, CaliforniaAges 18–55 - NCT06646627RecruitingPhase 1
B7-H3 car t cells for platinum-resistant ovarian cancer
This trial tests a new treatment where your own immune cells are modified to attack ovarian cancer cells that have stopped responding to platinum chemotherapy. It's for people with recurrent ovarian cancer that hasn't gotten better with standard treatments.
Palo Alto, CaliforniaAges 18 years+ - NCT06648174Recruiting
Managing heart health risk after gestational diabetes
This study tests a program to help women who had gestational diabetes reduce their future risk of heart disease and diabetes. It checks if monitoring and support can improve health after pregnancy.
HsinchuAges 18 years+ - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT06645470Recruiting
Muscle and movement study for weight loss medications
This study looks at how anti-obesity medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) affect your muscles and movement. It may help researchers understand how to combine these drugs with exercise for better health.
Kansas City, KansasAges 18 years+ - NCT06654323Recruiting
Behavioral program for childhood obesity
This study tests different levels of a behavioral program to help children with obesity lose weight and live healthier. Families will receive support and guidance over 12 months.
Baton Rouge, LouisianaAges 5–17 - NCT06652113Recruiting
Hydroxychloroquine with thyroid hormone for recurrent pregnancy loss
This study tests whether a combination of hydroxychloroquine (an anti-inflammatory drug) and levothyroxine (thyroid hormone) can improve live birth rates in women with recurrent pregnancy loss, normal thyroid function, and TPO antibodies.
Guangzhou, GuangdongAges 20–40 - NCT06649084Enrolling by invitation
Language treatment study for primary progressive aphasia
This study tests a multi-component language treatment for people with primary progressive aphasia (a type of dementia that first affects language). It aims to help improve communication skills with support from a study partner.
Austin, TexasAges Any age - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT06636383Recruiting
A follow-up study for people with GSDIa who received DTX401
This study monitors the long-term health of people with Glycogen Storage Disease Type Ia who have already received the gene therapy DTX401, either in a previous clinical trial or after it was approved. The goal is to gather more information about their condition over time.
Orange, CaliforniaAges 2 years+ - NCT06643130RecruitingPhase 3
Testing a combo treatment for high blood pressure and cholesterol
This study tests whether adding two medications together helps people who have both high blood pressure and high cholesterol. It aims to see if the combination works better and is safe.
SeoulAges 19 years+ - NCT06637137Recruiting
Blood management for cardiac surgery patients
This trial studies a program to manage blood levels before, during, and after heart surgery. It may help reduce the need for blood transfusions and improve recovery.
RomaAges 18 years+ - NCT06641141Recruiting
Wait or induce at 38 weeks for gestational diabetes
This trial compares two approaches for people with gestational diabetes: waiting for labor to start naturally versus inducing labor at 38 weeks. The goal is to see if one plan leads to better outcomes for both mother and baby.
Ottawa, OntarioAges 16 years+ - NCT06639724RecruitingPhase 1
Test of fostamatinib with chemo before and after surgery for pancreatic cancer
This trial tests adding a new drug, fostamatinib, to standard chemotherapy before and after surgery for pancreatic cancer that can be removed. The goal is to see if the combination helps reduce the chance of cancer coming back.
La Jolla, CaliforniaAges 18 years+ - NCT06633380Recruiting
Different physical activity strategies for breast cancer survivors
This study tests different ways to add physical activity into your daily routine to help manage side effects from breast cancer treatment. The goal is to see if simple, practical strategies can improve your health and well-being while you are on aromatase inhibitors.
Toronto, OntarioAges Any age - NCT06636773Recruiting
Aerobic vs Aerobic Plus Yoga for Weight Loss
This study compares two exercise programs — aerobic exercise alone versus aerobic exercise combined with yoga — to see which helps adults with overweight or obesity lose weight. You would need to follow a diet plan and attend regular exercise sessions at the University of Kansas Medical Center.
Kansas City, KansasAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.