Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06191094Enrolling by invitationPhase 4
Vabysmo before eye surgery for bleeding in diabetes
This trial tests if an injection of Vabysmo (faricimab) given before surgery can help people with eye bleeding from diabetic retinopathy. It aims to reduce blood in the eye and improve surgery outcomes.
Aurora, ColoradoAges 18 years+ - NCT06203847Recruiting
Prehospital drug combo for cardiac arrest
This trial tests whether a combination of three medications (epinephrine, vasopressin, and a steroid) given by paramedics before arriving at the hospital can improve survival for adults who have a cardiac arrest outside of a hospital. It is only for patients who are treated by specially trained paramedics and meet specific medical criteria.
TaipeiAges 18 years+ - NCT06200961Recruiting
Trans-nasal endoscopy for bariatric patients
This study tests a thinner, more comfortable endoscope that goes through the nose instead of the mouth for patients who need an upper GI exam. It may be a gentler option for weight-loss surgery patients.
Boston, MassachusettsAges 18–90 - NCT06185296Recruiting
Smart diabetes monitoring to help insulin users
This trial tests a smart phone-based system that helps doctors monitor diabetes and adjust insulin treatment. It could make blood sugar control easier for people with type 2 diabetes.
Aalborg, North JutlandAges 18 years+ - NCT06193369Recruiting
Digital peer support for young adults with cancer
This trial connects you with a trained peer (someone who has been through cancer) who provides support and guidance online. It's for young adults who finished treatment for certain cancers in the past year.
Toronto, OntarioAges 18–40 - NCT06183307Recruiting
Nattokinase for heart health in people with high cholesterol
This trial tests whether nattokinase, a natural enzyme, can reduce inflammation and improve heart health in people with high cholesterol or high triglycerides. If you have elevated LDL or triglycerides, you may be eligible even if you are already taking cholesterol medication.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06205953Recruiting
European registry for newly diagnosed AL amyloidosis
This study collects information and samples from people newly diagnosed with AL amyloidosis who have not yet received treatment. It aims to improve how this rare disease is diagnosed and managed across Europe.
HeidelbergAges 18–99 - NCT06192979Recruiting
First-line treatment for AL amyloidosis with t(11;14)
This study tests a new combination of medicines (daratumumab, bortezomib, and dexamethasone) as the first treatment for people with a specific type of amyloidosis (AL amyloidosis). It aims to see if this combination works better than standard care.
Beijing, Beijing MunicipalityAges Any age - NCT06197165Recruiting
Shiatsu for amyloidosis symptoms and quality of life
This study tests whether shiatsu (a gentle Japanese touch therapy) can improve symptoms and quality of life for people with amyloidosis. If you have a bothersome symptom like pain, shortness of breath, or anxiety, this trial may help you feel better.
CréteilAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06205849RecruitingPhase 1
Testing a new drug and procedure for advanced pancreatic cancer
This trial tests a new drug called mitazalimab injected directly into the tumor, combined with a special electrical procedure that kills cancer cells. It is for people whose pancreatic cancer has not spread but cannot be removed by surgery.
La Jolla, CaliforniaAges 18 years+ - NCT06186869Recruiting
Diet and exercise for fatty liver disease
This study tests whether combining diet with two different exercise programs can help people who are overweight or obese and have fatty liver disease. The goal is to see which program works best to reduce liver fat and improve health.
Castellana Grotte, BariAges 18–65 - NCT06198725Recruiting
Gut bacteria treatment for children with new type 1 diabetes
This study tests whether a special treatment aimed at gut bacteria can help children newly diagnosed with type 1 diabetes. It is for kids ages 6 to 12 who were diagnosed in the last 6 months and do not have other serious health conditions.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT06190626Recruiting
A study of eye disease in Zellweger spectrum disorder over time
This study follows people with Zellweger spectrum disorder (ZSD) to understand how their eye condition develops over time. It aims to help doctors treat the disease better in the future.
Rochester, New YorkAges Any age - NCT06191198RecruitingPhase 2
Communication Bridge 3: Speech therapy for PPA
This study tests a web-based speech therapy program called Communication Bridge for people with Primary Progressive Aphasia (PPA) and their communication partners. The goal is to improve communication skills and quality of life.
Chicago, IllinoisAges 18–100 - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT03228732RecruitingEarly Phase 1
Fluoxetine and/or DHEA in people with type 1 diabetes
This early-stage study tests whether the medicines fluoxetine and/or DHEA can improve health in adults with type 1 diabetes. It’s mainly looking for people without major diabetes complications or major medical problems to safely study the effects.
Baltimore, MarylandAges 18–50 - NCT04917601Recruiting
Digital coaching for childhood obesity with family app support
This study tests a digital support system (a mobile app) to help children and families with obesity treatment. You may be able to use the app alongside the usual care plan if you meet the study’s age, health, and communication requirements.
MessinaAges 4–17 - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06172621Recruiting
Spinal cord stimulation study for ALS hand weakness
This study tests whether combining brain and spinal cord stimulation can improve hand function in people with ALS who have partial weakness but still some movement in their fingers. The goal is to see if this non-invasive approach can strengthen nerve connections.
The Bronx, New YorkAges 18–80 - NCT06161025RecruitingPhase 2/Phase 3
Raludotatug Deruxtecan for resistant ovarian cancer
This study tests a new drug called Raludotatug Deruxtecan (R-DXd) for people with ovarian, fallopian tube, or primary peritoneal cancer that has stopped responding to platinum-based chemotherapy. The goal is to see if R-DXd can shrink tumors or slow cancer growth.
Anchorage, AlaskaAges 18 years+ - NCT06172478RecruitingPhase 2
HER3-DXd for advanced solid tumors after prior treatment
This trial tests a new targeted drug called HER3-DXd for people with several types of advanced solid tumors that have stopped responding to standard treatments. The drug is an antibody-drug conjugate, designed to deliver chemotherapy directly to cancer cells that have a protein called HER3 on their surface.
Duarte, CaliforniaAges 18 years+ - NCT06158854RecruitingPhase 1/Phase 2
Study of etentamig (ABBV-383) for AL amyloidosis
This study tests a new drug called etentamig (ABBV-383) given through a vein to see if it can control disease activity in people with AL amyloidosis who have already tried other treatments. It may help if your disease has progressed or is not responding well to prior therapies.
Miami, FloridaAges 18 years+ - NCT06164730RecruitingPhase 1
Study of VERVE-102 for high cholesterol or early heart disease
This trial tests a new medicine called VERVE-102 for people with a specific type of high cholesterol (HeFH) or early coronary artery disease. It aims to see if it can help lower cholesterol levels.
Dothan, AlabamaAges 18–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.