Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT04049084Enrolling by invitation
Follow-up study for people treated with gene therapy for ADA-SCID
This is a follow-up (no new treatment) study for people who previously received a gene therapy made from their own cells for ADA-SCID. It mainly tracks long-term safety and whether a marker showing the gene change can still be found.
Los Angeles, CaliforniaAges Any age - NCT04053478Recruiting
Testing common blood-pressure drugs on uterine and umbilical muscle
This study tests how several medicines used for blood pressure affect muscle “tightening” in tissue taken during planned C-sections. It’s an in-vitro (lab) study, so it mainly helps doctors understand how to prevent weak uterine contractions (uterine atony) during delivery.
Toronto, OntarioAges 19–40 - NCT03375866Recruiting
Mixed nuts trial to help you feel full and manage weight
This trial tests whether eating a mix of nuts helps people feel full longer (satiety) and manage weight. It may be most helpful if you are trying to improve weight control and can safely eat nuts.
San Diego, CaliforniaAges 18–55 - NCT03956602Recruiting
Snack choices and their effect on blood sugar
This trial studies how different snack types affect quick changes in blood sugar and insulin. It may help researchers understand which snacks cause smaller or larger spikes after eating.
San Diego, CaliforniaAges 18–55 - NCT03995238Recruiting
Gait training for veterans with leg amputations
This study tests a walking rehabilitation plan to improve how you walk after a lower-leg amputation. It may help if your walking steps are uneven and you have diabetes and/or circulation problems in your legs.
Aurora, ColoradoAges 40–89 - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03972345Enrolling by invitation
Study on how sticking to growth hormone affects near adult height
This study looks at whether consistently taking growth hormone (Norditropin) helps children reach a height goal by “near final height.” It focuses on children who are short due to growth hormone deficiency or born small for gestational age.
UlmAges birth–15 years - NCT03969329RecruitingPhase 3
Etelcalcetide for children on dialysis with high parathyroid hormone
This Phase 3 trial tests etelcalcetide to lower a hormone called parathyroid hormone (PTH) in children who have kidney disease and secondary hyperparathyroidism while on hemodialysis. It may help control bone/mineral problems, but the study also checks heart rhythm safety and medication stability.
GhentAges 2–17 - NCT03893045RecruitingPhase 3
Ferumoxytol for iron deficiency anemia in children
This trial tests ferumoxytol, an intravenous iron medicine, to treat iron deficiency anemia in children who cannot take or did not respond well to iron by mouth. It aims to improve blood iron levels and anemia symptoms safely.
Little Rock, ArkansasAges 2–17 - NCT03917043RecruitingPhase 1
Testing a new targeted drug for ALK or ROS1 lung cancers
This Phase 1 trial tests APG-2449, a new drug, in people with advanced solid tumors—especially certain lung cancers that have ALK or ROS1 gene fusions. Because it’s an early safety-and-dose study, it may help learn how well the drug works and what doses are safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04008121RecruitingEarly Phase 1
Testing an eye imaging drug during retinal blood-vessel photos
This early safety study tests how well and how safely an investigational dye (MB-102) works during a special eye imaging test of retinal and choroidal blood vessels. It compares it to the commonly used fluorescein dye and may help doctors refine future eye imaging approaches.
Ann Arbor, MichiganAges 18 years+ - NCT03994367Recruiting
Study of diet protein types and how they affect blood sugar
This study looks at how eating more or different types of proteins (animal vs plant) may change your blood sugar handling. It mainly targets adults who eat relatively little protein and have no diabetes.
Columbia, MissouriAges 21–70 - NCT03968406RecruitingPhase 1
Talazoparib plus radiation for recurrent gynecologic cancers
This Phase 1 study tests whether the cancer drug talazoparib, combined with radiation, can better control recurrent gynecologic cancers in the pelvis/abdomen. It focuses on patients whose cancer has come back locally enough that radiation can be given, while other disease is not rapidly worsening.
Baltimore, MarylandAges 18 years+ - NCT03943316Recruiting
Testing new cancer treatments on cells from ovarian cancer fluid
This laboratory study uses ovarian cancer fluid collected during surgery to test possible new treatments on cancer and immune cells. It may help researchers find better treatment options in ovarian cancer.
Albuquerque, New MexicoAges 18 years+ - NCT03882580Recruiting
Heart care during cancer treatment
This trial looks at how a special heart clinic can help cancer patients avoid or manage heart problems caused by their cancer treatment. It aims to find the best ways to detect, prevent, and treat heart issues during cancer care.
Paris, FranceAges 18 years+ - NCT04005690RecruitingEarly Phase 1
Targeted drug treatment for pancreatic cancer using pathway changes
This early-phase trial tests how well targeted medicines (and possibly an immunotherapy drug) work for people with pancreatic cancer that can’t be fully removed with surgery or has spread. It also looks at whether the treatment is safe and can shrink or control tumors by blocking specific cancer pathways.
Portland, OregonAges 18 years+ - NCT03970720RecruitingPhase 2
Metoclopramide to improve low-blood-sugar warning in type 1 diabetes
This Phase 2 study tests whether metoclopramide can help people with type 1 diabetes better notice when their blood sugar is getting too low. If low-blood-sugar warning is unreliable for you, this could help improve safety and control.
Lexington, KentuckyAges 20–60 - NCT04003038Recruiting
Negative pressure wound dressings after breast reconstruction in obesity
This trial tests whether a special “suction” dressing (negative pressure wound therapy) helps wounds heal better after breast reconstruction using tissue from the belly, especially in people with higher body weight. You may be more likely to benefit if you’re at higher risk for wound problems after abdominal flap surgery.
Houston, TexasAges 18 years+ - NCT03883412RecruitingPhase 4
Exercise and liraglutide for type 2 diabetes
This study tests if combining exercise with a drug called liraglutide improves blood vessel health and insulin sensitivity in people with type 2 diabetes. It looks at whether these treatments work better together or alone.
Charlottesville, VirginiaAges 21–60 - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT04011982Recruiting
Study of tissue analysis after pancreatic cancer surgery
This trial studies and analyzes tissue samples from people who had surgery for exocrine pancreatic (pancreatic duct-type) cancer. It may help researchers better understand the disease biology and improve future care.
LyonAges 18 years+ - NCT03937453Recruiting
Pancreatic cancer screening for people with new or worsening diabetes
This study checks whether regular imaging can find pancreatic cancer earlier in people who recently developed diabetes or whose diabetes is getting worse. It may help detect pancreatic problems sooner when treatment options are likely better.
New Haven, ConnecticutAges 50 years+ - NCT03927638Enrolling by invitation
Standing versus sitting study for heart and metabolism measures
This trial compares how different body positions (sitting vs standing) affect blood and heart-related measurements in otherwise healthy adults. It may help researchers understand which position is better for metabolic and cardiovascular health.
Montclair, New JerseyAges 18–50 - NCT03878706Recruiting
Testing diabetes medicines on heart risk and heart failure
This trial studies how diabetes medicines (GLP-1 and SGLT2, alone or together) affect the heart in people with type 2 diabetes who are at higher cardiovascular risk and have heart failure with preserved pumping function. It may help find safer or more effective ways to reduce heart problems.
Athens, AtticaAges 45–80
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.