Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT00899626Recruiting
Collecting stool and tissue markers from people with bowel conditions
This study collects samples (like tissue and other body fluids) from people who are getting a colonoscopy or similar camera test. It aims to find “biomarkers,” which are measurable signals that may help doctors better understand or detect bowel problems such as colorectal cancer, polyps, or inflammatory bowel disease.
Nashville, TennesseeAges 18 years+ - NCT01102556Recruiting
Pancreas disease registry for people at risk or with pancreatic cancer
This study collects health information and stored samples (biospecimens) to learn more about pancreatic diseases, including cancer and early warning changes. It may help researchers understand who is at higher risk and improve future testing and care.
New York, New YorkAges 18–85 - NCT00983463Enrolling by invitation
Study of liver fats and proteins in fatty liver disease
This study measures different fats and proteins in the liver of people with fatty liver disease (often called NAFLD) who are having planned abdominal or weight-loss surgery. It may help doctors better understand what’s happening in the liver and improve future care.
Nashville, TennesseeAges 18–65 - NCT01113216Enrolling by invitation
Genetics study for diabetes in cystic fibrosis families
This study looks at genetic (inherited DNA) factors that may influence who develops diabetes related to cystic fibrosis. Your results could help doctors better predict risk and improve care for cystic fibrosis and related diabetes.
Chicago, IllinoisAges 3 months–99 years - NCT00317616Recruiting
Study for people at high risk of ALS before symptoms start
This study follows healthy people from families with a known ALS-causing gene mutation to look for early body or brain changes before symptoms begin. It may help researchers find ways to predict ALS risk earlier so future treatments can start sooner.
Miami, FloridaAges 18 years+ - NCT00001595Recruiting
Study of pituitary tumors and related hormone gland disorders
This research study investigates tumors and disorders of the pituitary gland (a small gland that controls many body hormones) and related areas of the brain. You may qualify if you have a pituitary tumor or disorder, or if you have a family history of these conditions.
Bethesda, MarylandAges 2–70 - NCT00250159Recruiting
Natural history study for hormone-related excess androgen
This study follows people who may have too much “androgen” (a hormone) to learn what causes it and how it changes over time. You may be followed even if the exact cause is not yet known, and your results may help doctors better understand these conditions.
Washington D.C., District of ColumbiaAges 1 day–99 years - NCT01143454Recruiting
Study unusual heart conditions and related genetic traits
This study looks at people with unusual or rare heart problems, or people with a family history of these issues. Doctors and researchers may collect and study your blood or tissue (and possibly store samples) to learn what causes the condition and how it may affect the heart.
Washington D.C., District of ColumbiaAges 1–100 - NCT00001160Recruiting
Study of thyroid lumps and thyroid cancer
This study looks at people who have or may have thyroid nodules (lumps in the thyroid gland in your neck) or thyroid cancer, as well as family members who may have inherited a higher risk. It aims to better understand and diagnose these thyroid problems.
Bethesda, MarylandAges 6 months–98 years - NCT01186913Enrolling by invitation
Natural history study for severe combined immune deficiency (SCID)
This study follows children and adults with SCID and related immune disorders to understand how the illness behaves over time. It also helps researchers learn which testing results and genetic types of SCID match different treatment plans.
Birmingham, AlabamaAges Any age - NCT00005917Recruiting
Understanding Chediak-Higashi Syndrome: A Research Study
This study helps researchers understand Chediak-Higashi syndrome, a rare genetic condition that affects how the body fights infections and controls bleeding. Participation involves medical evaluation and may help guide future treatments.
Bethesda, MarylandAges 1 month–70 years - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100 - NCT00071526Recruiting
How the body loses vitamin C in diabetes
This study looks at why people with diabetes may lose more vitamin C in their urine than people without diabetes. By understanding this difference, researchers hope to better understand how diabetes affects the body's nutrition.
Bethesda, MarylandAges 18–65 - NCT00004847RecruitingPhase 1
Understanding and Diagnosing Pheochromocytoma and Paraganglioma
This study helps doctors better understand and diagnose pheochromocytoma and paraganglioma—rare tumors that release stress hormones and cause high blood pressure and other symptoms. Researchers will study your medical history, blood and urine tests, imaging scans, and genetic information to improve how these conditions are found and understood.
Bethesda, MarylandAges 3–120 - NCT00001987Recruiting
Understanding genetics of insulin resistance and diabetes
This research study looks at the genes and immune system factors that cause severe insulin resistance—a condition where the body doesn't respond well to insulin. Researchers want to understand why some people develop this problem and study family members and healthy volunteers to learn more.
Bethesda, MarylandAges 6 months–120 years - NCT00001276Recruiting
Understanding and Treating Severe Low Blood Sugar
This study helps doctors diagnose and treat dangerously low blood sugar, especially in people with pancreatic tumors that produce too much insulin. You'll receive comprehensive evaluation and personalized care to manage your condition.
Bethesda, MarylandAges 18–120 - NCT00353782Recruiting
Studying causes and course of lipid disorders
This study looks at the causes and natural history of different types of lipid disorders (abnormal cholesterol and fat levels in the blood). It aims to understand why these conditions happen and how they affect health over time.
Bethesda, MarylandAges 2–100 - NCT01247597Recruiting
Study of DICER1-related tumor history in families
This study follows people affected by DICER1-related tumors (and sometimes family members) to better understand how these conditions develop over time. It may help families by improving knowledge and guiding genetic counseling and future care.
Bethesda, MarylandAges 1 month–99 years - NCT00060541Recruiting
Evaluation and treatment of brain and nerve surgery conditions
This is a research program at the National Institutes of Health that evaluates and treats people with surgical brain and nerve conditions—like brain tumors, epilepsy, Parkinson's disease, and chronic pain. You'll receive expert evaluation and care while helping doctors learn more about these disorders.
Bethesda, MarylandAges 4–99 - NCT00005909Recruiting
Understanding Alkaptonuria: A Research Study
This study examines alkaptonuria, a rare inherited condition where the body cannot break down certain amino acids, leading to dark urine and joint problems. Researchers want to learn more about how this disease develops and progresses to improve future treatments.
Bethesda, MarylandAges 2–115 - NCT00078078Recruiting
Understanding Methylmalonic Acidemia and Cobalamin Disorders
This research study follows patients with methylmalonic acidemia (a rare metabolic disorder affecting how the body breaks down certain proteins) or cobalamin (vitamin B12) disorders to better understand how these conditions develop and progress over time. Researchers will collect medical information, blood samples, and eye exams to help improve future treatments.
Washington D.C., District of ColumbiaAges 1 month–115 years - NCT00895271Enrolling by invitation
Making lab cell lines from skin biopsies in immune disorders
This study creates special lab cell lines from skin (or nasal) samples from people with immune system disorders and certain family members. It’s meant to help researchers build tools to better study these conditions using patient cells.
Bethesda, MarylandAges 2–85 - NCT00428987Recruiting
Study of body and behavior traits in weight groups
This study looks at how physical traits and everyday behaviors differ among people who are overweight, obese, or in the normal-weight range. It may help researchers better understand risk factors related to weight and health.
Bethesda, MarylandAges 18–100 - NCT00369421Recruiting
Diagnosis and care for inherited metabolic conditions
This trial helps evaluate people who may have an inherited (genetic) metabolic or related disorder, and sometimes includes treatment or guidance based on the diagnosis. It may involve blood and urine testing, and participation can include in-person visits or telehealth.
Bethesda, MarylandAges 1 month–115 years
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.