Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07732738Recruiting
Bariatric surgery plus GLP-1 drug for weight loss and diabetes
This study tests if adding a GLP-1 medication to weight-loss surgery helps people with obesity and related conditions like diabetes. It may improve weight loss and blood sugar control more than surgery alone.
Xingtai, HebeiAges 16–70 - NCT07738029Recruiting
Intensive lifestyle treatment for children with obesity and their families
This trial studies a 1-year intensive lifestyle program for children ages 10-16 with a high body mass index (ISO-BMI ≥30) and their families. It aims to help children who have struggled to lose weight with lifestyle changes alone.
Tampere, PirkanmaaAges 10–16 - NCT07734870RecruitingPhase 2
Tirzepatide for treating scarring hair loss (CCCA)
This study tests whether tirzepatide (Mounjaro) can help treat a specific type of scarring hair loss called CCCA. It is for people whose hair loss is still active and who are not taking diabetes or weight-loss medications.
Baltimore, MarylandAges 18–80 - NCT07739524Recruiting
Iron levels in older adults with serious infections
This study checks iron levels in adults aged 75 and older during a severe infection to find and possibly treat iron problems. It may help improve recovery by managing iron better.
Orléans, LoiretAges 75 years+ - NCT07733505RecruitingPhase 1
Heated chemotherapy for older women with advanced ovarian cancer
This trial tests a new way to give heated chemotherapy directly into the abdomen during surgery for women aged 70 and older with advanced ovarian cancer. It aims to find a gentler treatment option that may still be effective for those who are more frail.
OdenseAges 70 years+ - NCT07736937RecruitingPhase 1/Phase 2
Study of TUB-040 with Standard Drugs for Ovarian Cancer
This study tests a new medicine called TUB-040, given together with standard ovarian cancer drugs like carboplatin and bevacizumab. It is for women with ovarian cancer that has returned after responding to platinum-based chemotherapy and is growing again. The goal is to see if this combination can help control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07738107RecruitingPhase 1/Phase 2
Study of ATR 1072 for PRKAG2 syndrome
This trial tests a new medicine called ATR 1072 for people with PRKAG2 syndrome, a genetic heart condition. It aims to see if the drug is safe and can help manage symptoms.
Kansas City, MissouriAges 18–65 - NCT07734311RecruitingPhase 3
Testing a weight-loss injection for knee arthritis pain
This study tests whether an experimental weight-loss injection can reduce knee pain in people who are obese and have knee osteoarthritis. It may help if you have been unable to lose weight through diet and exercise and have moderate knee pain.
Wuhan, HubeiAges 18–75 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07733674RecruitingPhase 1
Testing a new imaging agent for brain and pancreatic tumors
This early-phase study tests a new imaging agent that may help see certain solid tumors (like brain cancer or pancreatic cancer) more clearly. You will receive a single injection of a radioactive tracer, then have several scans over a few days to see where the tracer goes and how long it stays.
Houston, TexasAges 18 years+ - NCT06318442Recruiting
Preventing steroid-induced diabetes with a GLP-1 drug
This study tests whether a GLP-1 medication (a type of drug that helps control blood sugar) can prevent diabetes caused by steroid treatments. It is for people who have prediabetes or mild diabetes and are about to receive a short course of steroids.
LondonAges 18 years+ - NCT06623500Recruiting
Iodine levels and health in thyroid cancer patients
This study looks at how iodine levels in your diet relate to thyroid cancer. If you have already had surgery for thyroid cancer, doctors will review your medical records and follow your health over time.
Jinan, ShandongAges 18–65 - NCT05196334Recruiting
Testing pancreatic lab samples to guide future treatments
This study uses small pancreatic cancer samples grown in the lab to understand which treatments may work best for people with pancreatic cancer. It may help researchers better “profile” tumors so standard care can be matched to the most effective options.
Herlev, CopenhagenAges 18 years+ - NCT05974995Recruiting
Robotic or standard surgery for early uterine cancer in obesity
This trial compares robotic-assisted surgery versus standard laparoscopic surgery for people with early-stage uterine (endometrial) cancer and a BMI of 30 or higher. The goal is to see which approach is safer and works better for this group.
RomeAges 18–75 - NCT06626113Recruiting
Nerve activity and obesity study
This trial looks at how the nerves that control blood pressure work in people with obesity and insulin resistance. It may help explain why some people develop high blood pressure and others don't.
Kansas City, KansasAges 18–79 - NCT06499623Recruiting
Early detection of malnutrition in cancer and older patients
This study tests a way to spot malnutrition early in cancer patients and older adults who are in the hospital. It aims to help doctors catch and treat nutrition problems sooner.
BrnoAges 18 years+ - NCT06395246Recruiting
Weight loss and tiny cell particles study
This study looks at how weight loss from a special diet affects tiny particles in your blood, called microvesicles, that help control your body's energy use. It may help us understand why weight loss improves health for people with obesity.
Tarragona, TarragonaAges 18–70 - NCT04571294Recruiting
Removing lymph nodes during Whipple surgery for pancreatic cancer
This study looks at removing certain lymph nodes near the aorta while doing a standard Whipple operation for pancreatic head cancer. The goal is to see whether this approach can improve how well doctors manage the cancer spread.
Rozzano, Italy/MilanAges 18 years+ - NCT06627998Recruiting
Bone health study for thyroid cancer patients
This study checks how common bone problems are in people with thyroid cancer. It uses a chest x-ray done before surgery to look at the spine's shape.
MilanAges 18 years+ - NCT07725809RecruitingPhase 1
Study of a new medicine for adults with overweight or obesity
This study tests a new medicine called PF-08653945 to see how it enters the blood in adults who are overweight or have obesity. The results will help doctors understand how the medicine works in the body.
Brussels, Bruxelles-capitale, Région deAges 18 years+ - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07727538RecruitingPhase 3
Olezarsen for familial chylomicronemia syndrome in children and teens
This study tests a new medicine called olezarsen to lower very high triglycerides (fats) in the blood of children and teenagers with familial chylomicronemia syndrome (FCS), a rare genetic condition. The goal is to reduce the risk of pancreatitis and other complications.
Birmingham, AlabamaAges 2–17 - NCT07726368RecruitingPhase 1
Study of ECC4703 with sulfasalazine and pitavastatin
This early-phase study tests how a new drug (ECC4703) works in the body when taken with two other common medications (sulfasalazine and pitavastatin). Healthy volunteers are needed to help researchers understand potential drug interactions and safety.
Melbourne, VictoriaAges 18–65
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.