Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07723833RecruitingPhase 1
Study of different forms of elecoglipron in healthy volunteers
This trial tests how different versions of the drug elecoglipron are absorbed by the body and if they are safe. It is for healthy people to help find the best way to take the medicine.
Glendale, CaliforniaAges 18–55 - NCT07732400RecruitingPhase 1/Phase 2
Gene therapy for MASH (fatty liver disease)
This trial tests an experimental gene therapy (VV-14303) given as a single injection into the muscle to treat MASH, a common type of fatty liver disease with inflammation. The study will check if the treatment is safe and helps improve liver health.
Chandler, ArizonaAges 18–75 - NCT07731139RecruitingPhase 1
Testing a new medicine for people with obesity
This study tests how different amounts of the study medicine PF-08642534 are tolerated and how they work in the body of people with obesity. It aims to find a safe dose for future studies.
Lake Forest, CaliforniaAges 18–70 - NCT06353568Recruiting
Light therapy to prevent diabetic foot ulcers
This study tests a painless light treatment (photobiomodulation) to see if it can prevent foot ulcers in people with type 2 diabetes who are at risk. If you qualify, you would receive the treatment regularly and be monitored for foot health.
São Paulo, São PauloAges 18–75 - NCT07728032Recruiting
How diet and medicine affect gut health in PKU children
This study looks at how a phenylalanine-restricted diet or certain PKU medicines affect gut health in children with PKU. It also includes healthy siblings or household members as a comparison group.
Birmingham, BirminghamAges 3–17 - NCT07728240Recruiting
Diet, health, and exercise study
This study looks at how your diet and health affect your body's response to exercise. You'll do some thinking tests, record what you eat, and ride a bike at a moderate pace.
River Falls, WisconsinAges 18–60 - NCT07729982Recruiting
Study tracking vision changes in OPA1 optic atrophy
This study follows people with a genetic form of optic atrophy over time to understand how vision changes. It does not test a treatment but helps doctors learn more about the condition to improve care.
Munich, BavariaAges Any age - NCT07727512Recruiting
PCOS and Brain Health
This study uses brain imaging (MRI) to compare brain health in people with PCOS versus healthy volunteers. It aims to understand how PCOS may affect the brain and potentially guide future treatments.
Madison, WisconsinAges 18–45 - NCT07724106RecruitingPhase 1
NeoOVSV vaccine for ovarian cancer after surgery
This trial tests a personalized vaccine made from your own tumor tissue called NeoOVSV. It is meant to train your immune system to fight any remaining cancer after surgery. The vaccine is a personal treatment because it uses your tumor's unique markers.
Chengdu, SichuanAges 18–75 - NCT07726563Recruiting
Plasmapheresis for ALS with NRIP2 antibody
This trial tests whether a blood filtering treatment called plasmapheresis can help people with ALS who have a specific antibody (NRIP2) in their blood. It aims to see if removing this antibody can slow the disease and improve symptoms.
Taipei City, TaipeiAges 20 years+ - NCT07731438Recruiting
Calorie restriction and bone marrow fat in obesity and diabetes
This study tests whether a calorie-restricted diet can change the fat in your bone marrow and how it relates to bone health and energy use. It is for premenopausal women and men who are either obese or lean and do not have diabetes.
PragueAges 21–55 - NCT07726680Recruiting
Game for kids with new type 1 diabetes
This study tests a fun video game that connects to a continuous glucose monitor (CGM). The game helps kids newly diagnosed with type 1 diabetes learn about managing their condition in a playful way. Both the child and a parent need to join together.
Lahore, Punjab ProvinceAges 6–17 - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07731399Recruiting
Diabetes Study for Medicaid Members in South Carolina
This study collects blood samples and health information from people with type 2 diabetes and healthy controls to learn more about diabetes. It may help improve future care for diabetes.
Orangeburg, South CarolinaAges 40–70 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT05766098Recruiting
Genetic testing of papillary thyroid tumor samples
This trial studies the genetic “mutations” in papillary thyroid cancer tumors using tumor tissue. The goal is to better describe tumor genetic patterns, which may help researchers understand the disease.
Milan, MIAges Any age - NCT05149859Recruiting
Binge eating and severe obesity treatment after screening
This study looks at people with obesity, including those with binge eating disorder (BED). It compares groups based on their binge-eating questionnaires and tests a care approach at obesity and mental-health clinics.
QuébecAges 18–65 - NCT06630377Recruiting
Testing GOS for lowering high uric acid
This study tests whether a prebiotic called GOS (a type of dietary fiber) can help lower high uric acid levels naturally, without medication. If you have high uric acid and want a non-drug option, this trial may be a good fit.
Guangzhou, GuangdongAges 18–80 - NCT02647827RecruitingPhase 2
Acupuncture or metformin for insulin resistance in PCOS
This study tests whether acupuncture or the diabetes medicine metformin can improve insulin resistance in women with PCOS. It may help with hormone-related symptoms and metabolic health, comparing the two approaches against usual care for non-PCOS controls.
BeijingAges 18–40 - NCT05487534Recruiting
How sugar swings may affect brain and eating in type 1 diabetes
This study looks at whether changes in blood sugar (“sugar swings”) affect brain functioning and eating behaviors in adults with type 1 diabetes. You would likely track your blood sugar and complete computer-based tasks or questionnaires to help researchers understand these links.
MontrealAges 18–65 - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT04917471Recruiting
Testing nitrate to improve red blood cell function in type 2 diabetes
This study looks at whether taking nitrate can improve how red blood cells work in people with type 2 diabetes. You may be asked to follow a specific plan and avoid certain foods or medicines that could affect the results.
StockholmAges 18 years+ - NCT05602805Recruiting
Study using a health data bank for weight management
This study builds a data bank to help track how people manage overweight or obesity at the hospital. It may help improve care for future patients by learning what treatments and outcomes work best.
Québec, QuebecAges 18 years+ - NCT06175988Recruiting
Belly fat, nerve health, and food choices pilot study
This study looks at how belly fat and nerve signals affect food preferences. You'll taste and smell different things and have a check-up visit at a research center in Quebec City.
Québec, QuebecAges 18–45
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.