Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1557
- Phase 3417
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer289
- Type 2 Diabetes276
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2170
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight123
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer92
- Pancreas Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- Eli Lilly and Company40
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07743307Enrolling by invitation
Diabetes self-management with glucose monitoring
This study tests a program that uses a continuous glucose monitor (CGM), a small sensor that tracks your blood sugar in real time, along with group sessions to help adults with type 2 diabetes better manage their condition. It may help you understand how your daily choices affect your glucose levels.
Manhasset, New YorkAges 18 years+ - NCT07747428Recruiting
Eye imaging study for diabetic retinopathy
This study uses a special eye imaging test called OCT angiography to look at tiny blood vessels in the back of the eye. It aims to understand changes caused by diabetic retinopathy, which could help improve how we monitor and treat this condition.
SohagAges 18–80 - NCT07747896Recruiting
Coordinated primary care team for hard-to-heal wounds
This trial tests whether a team of different healthcare professionals working together in your primary care clinic can help heal stubborn wounds (ulcers) that have not healed with standard care. If you join, you may get more coordinated care and support to help your wound heal.
HillerødAges 18 years+ - NCT07747909Recruiting
Orlistat for metabolic and hormonal health in PCOS
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Abbottābād, Khyber PakhtunkhwaAges 18–45 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT03131726RecruitingPhase 3
Simvastatin for Graves eye disease in mild-to-moderate cases
This trial tests whether simvastatin (a cholesterol medicine) can improve eye symptoms from Graves’ eye disease. It is aimed at people with active mild-to-moderate disease and will also check safety with blood tests, heart/skin tolerance, and stomach health.
MalmöAges 18–70 - NCT06610604Recruiting
Thyroid nodule treatment and quality of life study
This study looks at how thyroid nodules affect your daily life and feelings after treatment. It compares quality of life in people who had microwave ablation versus those who had thyroid surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06611462Recruiting
Strong for surgery: prehab before hernia repair
This trial tests a 4-week program of exercise, nutrition, and lifestyle support before ventral hernia surgery to help reduce complications. If you have a hernia smaller than 8 cm and at least one health risk factor, this might help you prepare for a safer recovery.
HerlevAges 18 years+ - NCT06616545Recruiting
French study on type 3 Glycogen storage disease
This study tracks the health of people with type 3 Glycogen storage disease. It may help doctors understand the disease better and plan better care.
ClamartAges Any age - NCT06619301RecruitingPhase 3
Insulin options for diabetes in pregnancy
This trial compares two types of insulin (glargine and NPH) to see which works better for managing blood sugar in pregnant women with gestational diabetes or type 2 diabetes. If you need to start insulin during pregnancy, you may be able to join.
Maywood, IllinoisAges 18 years+ - NCT05769868RecruitingPhase 3
Esmolol test to spot heart problems in diabetes, cirrhosis, and cancer
This trial tests whether esmolol (a short-acting heart medicine) can help doctors identify certain heart-related problems in people with type 2 diabetes, liver scarring (cirrhosis), or specific cancers. It’s mainly about improving how heart issues are detected during ultrasound testing.
Barcelona, BarcelonaAges 18 years+ - NCT04265599Recruiting
Study of high calcium after oil injections
This study looks at why some people develop high blood calcium after receiving an oil injection into a muscle. It may help researchers understand the cause and find better ways to treat it.
CopenhagenAges 18 years+ - NCT06418477RecruitingPhase 2
A study of 4 drugs for a rare kidney disease
This trial tests a combination of four medications (daratumumab, bortezomib, cyclophosphamide, and dexamethasone) for people with monoclonal immunoglobulin deposition disease (MIDD), a condition where abnormal proteins build up in organs. The goal is to see if this treatment can help without prior harsh therapies.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06616714Recruiting
Weight loss procedure for people with obesity and IBD
This study tests a weight-loss procedure called endoscopic sleeve gastroplasty (a stomach-reducing procedure done through a scope) in people with both obesity and inflammatory bowel disease (IBD). It aims to see if the procedure is safe and helpful for this group.
RomaAges 18–70 - NCT05477212Recruiting
Study gut leakiness in obesity and fatty liver with a ketogenic diet
This study looks at “gut permeability,” sometimes called intestinal leakiness, in people with obesity and fatty liver disease. It tests whether a ketogenic (very low-carb) diet changes gut leakiness and fatty liver measurements.
Castellana Grotte, BARIAges 18–65 - NCT07734090Recruiting
Understanding MADD over time
This study follows people with MADD over time to understand how the condition changes, with the goal of improving future care and treatment. It does not test a new medication – it collects information through visits and tests.
Aurora, ColoradoAges Any age - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07736911RecruitingPhase 3
Should you pause your diabetes medication before a stomach scope?
This trial is testing whether stopping GLP-1 receptor agonists or tirzepatide one week before an upper endoscopy (a scope that looks at your stomach and esophagus) is safe and effective. It's designed for people who are already taking these medications and have an upcoming procedure.
New Taipei City, TaiwanAges 18–90 - NCT07737561Recruiting
Exercise test for heart, kidney, and metabolic health
This study looks at how blood pressure and artery stiffness respond to exercise in people with heart, kidney, and metabolic problems. It may help doctors better understand your condition.
KaramanAges 18 years+ - NCT07732777Recruiting
AI-assisted insulin pump study for type 1 diabetes
This study tests whether an artificial intelligence (AI) system can help manage insulin pump therapy remotely for people with type 1 diabetes. The goal is to improve blood sugar control and make diabetes management easier.
Nanjing, JiangsuAges 14–65 - NCT07733505RecruitingPhase 1
Heated chemotherapy for older women with advanced ovarian cancer
This trial tests a new way to give heated chemotherapy directly into the abdomen during surgery for women aged 70 and older with advanced ovarian cancer. It aims to find a gentler treatment option that may still be effective for those who are more frail.
OdenseAges 70 years+ - NCT07733375Recruiting
Smart wristband to guide thyroid hormone after thyroid surgery
This study tests whether a smart wristband can help doctors see how well your thyroid medicine (levothyroxine) is working after you have your thyroid removed. You will wear the wristband and have your heart rate tracked, and the results might help make your treatment more precise.
Istanbul, KadıköyAges 18 years+ - NCT07737340Recruiting
Metabolic liver disease in new HIV patients
This study looks at liver health in people newly diagnosed with HIV, before they start HIV treatment. It aims to understand early changes in the liver related to metabolism.
Ankara, AnkaraAges 18 years+ - NCT07732738Recruiting
Bariatric surgery plus GLP-1 drug for weight loss and diabetes
This study tests if adding a GLP-1 medication to weight-loss surgery helps people with obesity and related conditions like diabetes. It may improve weight loss and blood sugar control more than surgery alone.
Xingtai, HebeiAges 16–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,814 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.