Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07554469Recruiting
Study of Finerenone for Kidney Disease in Type 2 Diabetes
This observational study tracks how well finerenone (a kidney-protective medication) works in adults with type 2 diabetes and chronic kidney disease in Spain. Researchers will measure changes in kidney function and disease risk over time to better understand the medication's real-world benefits.
Many LocationsAges 18 years+ - NCT07553351RecruitingPhase 3
Growth hormone treatment for children with growth hormone deficiency
This trial tests a new growth hormone medicine (GB06) for children whose bodies don't make enough growth hormone naturally. The study will see if this treatment helps children grow taller over time.
Chengdu, SichuanAges 3–11 - NCT06387199RecruitingPhase 2/Phase 3
Weekly semaglutide with closed-loop system for type 1 diabetes
This trial tests whether adding a weekly semaglutide injection (a GLP-1 drug) to a closed-loop insulin system can help reduce the need for carb counting in people with type 1 diabetes. It aims to improve blood sugar control and make diabetes management easier.
Montreal, QuebecAges Any age - NCT06576479Recruiting
Supplement study for kidney disease and weight loss
This study tests if a special drink can improve nutrition and quality of life in people with chronic kidney disease (CKD) who are not on dialysis. It is for those who have lost weight or have poor appetite.
Guadalajara, JaliscoAges 18–90 - NCT06739135Recruiting
Driving with diabetic neuropathy study
This study looks at how diabetic neuropathy (nerve damage from diabetes) affects driving safety. You may join if you have type 2 diabetes with or without neuropathy and are an experienced driver in the UK.
ManchesterAges 25–69 - NCT06739473RecruitingPhase 4
How obesity affects glucose use in the body
This trial looks at how the body uses sugar (glucose) for energy in people with and without obesity. Results could help find better treatments for metabolic conditions.
TurkuAges 20–60 - NCT06742528Recruiting
Comparing two iron medicines for children with low iron
This study compares two iron medicines—one a simple iron pill and the other a gentle iron form—to see which works better for children with low iron levels (anemia). If your child has iron deficiency anemia and none of the listed health issues, they may be able to join.
Peshawar, KPKAges 6 months–5 years - NCT06742112Recruiting
Arm and Breathing Test for People Who Are Overweight
This study looks at how well people who are overweight or obese can use their arms and breathe while performing a 6-minute pegboard and ring test. Researchers want to see if this test can help measure physical function in this group.
KırşehirAges 18–65 - NCT05345327RecruitingPhase 3
First diabetes pill to protect kidneys
This Phase 3 trial tests whether starting a diabetes medicine called dapagliflozin can better slow kidney damage than starting metformin in adults with type 2 diabetes. It may help preserve kidney function over time and reduce future kidney decline.
Sydney, New South WalesAges 18 years+ - NCT07546929RecruitingPhase 2
HP-211 Safety Study for Type 2 Diabetes Treatment
This study tests a new medicine called HP-211 in people with early-stage type 2 diabetes to see if it's safe and helps control blood sugar. You'd take the study drug along with your current diabetes management.
Canoga Park, CaliforniaAges 18 years+ - NCT07550816RecruitingPhase 1
Safety study of ZT002 injection in overweight adults
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
Chengdu, SichuanAges 18–45 - NCT07548853RecruitingPhase 3
Testing TS-172 to Lower Phosphorus in Peritoneal Dialysis Patients
This study tests whether a new medicine called TS-172 can help lower phosphorus levels in patients on peritoneal dialysis (a type of kidney treatment). High phosphorus can cause bone problems and other complications, so the trial aims to see if this drug works better than current treatments.
TokyoAges 18 years+ - NCT07546500RecruitingPhase 3
Azenosertib versus chemotherapy for advanced ovarian cancer
This trial tests a new drug called azenosertib against standard chemotherapy for ovarian, fallopian tube, or peritoneal cancer that has come back after platinum-based treatment. The drug targets a specific protein (cyclin E1) found in some tumors and may help stop cancer cells from dividing.
Phoenix, ArizonaAges 18 years+ - NCT07543367Recruiting
Brain implant to restore arm movement in ALS
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
Jacksonville, FloridaAges 22 years+ - NCT07543731Recruiting
Study of how patients stick with cholesterol-lowering injection medications
This study follows people who are starting one of three injectable cholesterol medications (inclisiran, evolocumab, or alirocumab) to see how well they stick with treatment over time. Understanding medication adherence helps doctors and patients find ways to improve long-term health outcomes.
BaselAges 18–99 - NCT06323889Recruiting
Intermittent fasting study for adults with obesity
This study tests whether intermittent fasting (alternating periods of eating and fasting) can help with weight loss and health in adults with obesity. It aims to see if this approach is safe and effective.
Zurich, Canton of ZurichAges 18–50 - NCT06490822Recruiting
Skin study for frontotemporal lobe degeneration
This study looks at whether skin samples can help detect brain changes in people with frontotemporal lobe degeneration (a type of dementia) and related conditions. It compares skin from patients and healthy volunteers to find clues that might help with diagnosis.
NantesAges 50–75 - NCT06684327RecruitingPhase 2
Study of three chemotherapy drugs for rare advanced cancers
This trial tests a combination of three chemotherapy drugs (albumin-paclitaxel, ifosfamide, and cisplatin) for people with certain rare cancers that have spread to other parts of the body (stage IV). It looks at how well the treatment works and if it is safe.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07546409Recruiting
Do ketones help thinking in older adults with prediabetes?
This study looks at whether a supplement called ketones can improve thinking and memory in older adults who have prediabetes but not diabetes or memory problems. You will take the supplement, have brain scans, and complete thinking tests.
Birmingham, AlabamaAges 60–75 - NCT07550023Recruiting
How Different Dietary Fats Affect Your Gut Health
This study examines how different types of dietary fats influence the bacteria in your gut and how your body processes nutrients. By participating, you'll help researchers understand the link between fat intake and digestive health in healthy adults.
GlasgowAges 20–50 - NCT07543718Recruiting
Group Medical Visits for High Cholesterol Management
This trial tests whether attending group medical visits with other patients can help manage high cholesterol levels. You'll meet with a healthcare team and peers to learn about cholesterol and how to control it together.
Dieppe, New BrunswickAges 40 years+ - NCT07548996RecruitingPhase 2/Phase 3
Study of oral dimethyl fumarate for type 1 diabetes
This study tests an oral capsule called dimethyl fumarate to see if it can help preserve the body’s own insulin production in adults with type 1 diabetes. It may offer a way to slow the loss of beta cells and reduce reliance on insulin.
Nanjing, JiangsuAges 18–65 - NCT07547930RecruitingPhase 2
Tofacitinib for Steroid-Resistant Thyroid Eye Disease
This study tests whether tofacitinib, a new type of immune-modulating medication, can help people with moderate-to-severe thyroid eye disease (Graves' orbitopathy) whose eyes haven't improved with standard steroid treatments. The goal is to reduce eye swelling, bulging, and inflammation that affects daily life.
Xiamen, FujianAges 18–75 - NCT07543666Recruiting
Exercise and inflammation markers in healthy young adults
This study looks at how starting a structured exercise program affects inflammation in the body. Researchers want to understand the link between physical activity and inflammation markers in healthy young adults.
München, BavariaAges 18–45
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.