Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06280443Recruiting
Frailty and muscle loss in chronic lung disease
This study looks at people with COPD or ILD who also show signs of frailty. It aims to understand how frailty and muscle loss (sarcopenia) affect their care and use of medical resources over time.
TaichungAges 20 years+ - NCT06280742Recruiting
Brain inflammation in multiple sclerosis: a PET-MRI imaging study
This study uses a special PET-MRI scan to look at brain inflammation in people with relapsing-remitting multiple sclerosis (RRMS). It may help researchers understand how inflammation changes when starting a stronger MS treatment.
LyonAges 18 years+ - NCT06280872Recruiting
Cord clamping study for moderate and late preterm babies
This trial studies a different way of clamping the umbilical cord after birth to see if it helps moderately preterm babies (born between 32 and 37 weeks). It may improve their health right after delivery.
BrusselsAges 7 months–8 months - NCT06280755Recruiting
AI-assisted MS care study
This study looks at how artificial intelligence (AI) can help doctors care for people with multiple sclerosis (MS) and other similar conditions. It uses existing medical data to see if AI can improve treatment decisions.
Prague, Praha 2Ages 18 years+ - NCT06280924Recruiting
Exercise before or after stem cell transplant for multiple myeloma
This study tests whether a 10-week exercise program (prehab) before or after a stem cell transplant can help people with multiple myeloma feel stronger and recover better. You can join whether you are getting a transplant or not, as long as you live in Alberta and have internet access.
Edmonton, AlbertaAges 18 years+ - NCT06281327RecruitingPhase 2
Avatrombopag for children with ITP switching from eltrombopag
This trial tests a new platelet-raising medicine, avatrombopag, in children with ITP who have already tried eltrombopag. It aims to see if switching to avatrombopag can safely increase platelet counts and reduce bleeding.
TianjinAges 6–18 - NCT06282055Recruiting
Insulin sensitivity changes during menstrual cycles in type 1 diabetes
This study looks at how insulin sensitivity changes during the menstrual cycle in women with type 1 diabetes. It may help find patterns that could improve diabetes care.
BernAges 18–40 - NCT06283316Recruiting
A registry for alopecia areata treatments
This trial is a registry that collects information from people with alopecia areata who are starting or using body-wide treatments. It helps doctors learn more about how these treatments work in real life.
RotterdamAges 16 years+ - NCT06283797Recruiting
Automated insulin early after type 1 diabetes diagnosis in kids
This trial tests whether starting automated insulin therapy soon after diagnosis helps children and teens with type 1 diabetes control their blood sugar better. It uses a system that automatically adjusts insulin delivery based on continuous glucose monitoring.
AngersAges 2–18 - NCT06284122RecruitingPhase 3
New drug combo vs standard chemo for untreated follicular lymphoma
This study tests a new combination of two drugs (mosunetuzumab and lenalidomide) compared to standard chemo-immunotherapy for people with newly diagnosed follicular lymphoma that needs treatment. It aims to see if the new combination works better and has fewer side effects.
GrazAges 18 years+ - NCT06284395Recruiting
Comparing multiple myeloma treatment plans
This study looks at two different drug combinations for people with multiple myeloma who are eligible for a stem cell transplant. It aims to find which treatment works better.
Mexico City, Mexico CityAges 18–90 - NCT06286007Recruiting
How whooping cough and RSV affect asthma in adults
This study looks at how infections like whooping cough and RSV impact asthma symptoms and control in adults. It aims to understand if these infections make asthma worse, which could help improve future treatment and prevention.
Santiago de Compostela, A CoruñaAges 18–99 - NCT06285539RecruitingPhase 2
Testing a drug for rare inflammatory diseases
This trial is testing a new drug (a JAK inhibitor) for people with rare inflammatory diseases like Behçet's, myositis, or IgG4-related disease that hasn't improved with standard treatments. The goal is to see if it can help control symptoms and reduce inflammation.
AmsterdamAges 18–65 - NCT06286085Recruiting
Comparing asthma tests in Portsmouth
This study looks at different ways to test for asthma. It uses data from patients who have already been evaluated at the Portsmouth asthma service, to see which tests work best for diagnosing asthma.
PortsmouthAges 18 years+ - NCT06287528RecruitingPhase 1
CAR T‑cell therapy with IL‑18 for returning B‑cell leukemia
This trial tests a new type of CAR T‑cell therapy that also makes an immune‑boosting protein called IL‑18. It is for people with B‑cell acute lymphoblastic leukemia that has come back or not gone away after standard treatments.
Basking Ridge, New JerseyAges 17 years+ - NCT06287229RecruitingPhase 1/Phase 2
CAR T therapy for B-cell ALL after initial treatment
This trial tests whether a special immune cell therapy (brexucabtagene autoleucel, or CAR T therapy) can help people with B-cell acute lymphocytic leukemia (ALL) after reducing the number of leukemia cells with a chemo-immunotherapy combination. It is for patients whose cancer has returned or is hard to treat, or for those newly diagnosed with a high-risk form of ALL.
Houston, TexasAges 18 years+ - NCT06287398RecruitingPhase 2
Epcoritamab and chemo before stem cell transplant for relapsed large B-cell lymphoma
This trial tests a combination of a new immunotherapy drug called epcoritamab with chemotherapy, followed by a stem cell transplant and more epcoritamab, for people whose large B-cell lymphoma has returned after initial treatment. The goal is to see if this approach can help more people achieve remission and stay in remission.
Melbourne, VictoriaAges 18 years+ - NCT06288503Recruiting
Testing a rice formula for babies with cow's milk allergy
This trial tests a special formula made from rice proteins (hydrolyzed rice formula) for babies with cow's milk allergy. It may help manage symptoms while providing the nutrition your baby needs.
Gloucester, GloucestershireAges birth–1.1 years - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+ - NCT06290544Recruiting
Heart Risk Study for Italian Adults with Type 1 Diabetes
This study looks at heart health in adults with type 1 diabetes. By joining, you'll help doctors better understand how to prevent heart problems in people like you.
MilanAges 18 years+ - NCT06291428Recruiting
Comparing light-based test to standard test for leukemia detection
This study compares a new technique using light to detect leftover leukemia cells (Raman spectroscopy) with the standard method (flow cytometry) in people with acute lymphoblastic leukemia (ALL).
León, GuanajuatoAges 2–70 - NCT06292312Recruiting
Craniosacral therapy for multiple sclerosis
This study tests if a gentle hands-on treatment called craniosacral therapy can help people with multiple sclerosis feel better. It is for people with mild to moderate disability who are not having active relapses.
AnkaraAges 18–65 - NCT06294652Recruiting
Austrian Lymphoma Patient Registry Study
This registry collects information from adults with lymphoma to better understand the disease and improve future treatments. It is open to all patients 18 or older with lymphoma.
Salzburg, State of SalzburgAges 18 years+ - NCT06296121RecruitingPhase 3
BCD-264 vs Darzalex for relapsed multiple myeloma
This trial tests a new drug, BCD-264, compared to Darzalex (daratumumab) alone for people with multiple myeloma that has come back or stopped responding to prior treatments. The goal is to see if BCD-264 works better than Darzalex in controlling the cancer.
ChelyabinskAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.