Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT07505355Recruiting
Walking and foot tap test in multiple sclerosis
This study tests two simple walking and foot-tapping exercises to see how well they measure balance and mobility in people with multiple sclerosis. It aims to help doctors better track walking problems in MS.
DiepenbeekAges 18–65 - NCT07506746Recruiting
Study on esophagus movement
This study tracks patients with reflux, swallowing problems, or other esophageal symptoms to understand how the esophagus moves. It may help if you have heartburn, regurgitation, or related issues like cough or chest pain.
Milan, LombardyAges 18 years+ - NCT07507084Recruiting
Exercise with cognitive tasks for walking and balance in MS
This study combines exercise with a thinking activity to see if it improves walking, balance, and thinking skills in people with multiple sclerosis. It compares two types of exercise training to find which is more helpful for daily life.
Kütahya, MerkezAges 18–65 - NCT07507201RecruitingEarly Phase 1
Car-T cells for autoimmune diseases like lupus
This trial tests whether specially-engineered immune cells (CAR-T cells) can help people with certain autoimmune diseases that haven't gotten better with standard treatments. The cells are designed to target and remove faulty B cells that are causing the immune system to attack the body.
Hangzhou, ZhejiangAges 3 years+ - NCT07507318RecruitingPhase 2
Low-dose chemo to prevent relapse in high-risk DLBCL patients
This trial tests a low-dose chemotherapy pill (chidamide) for people with a certain high-risk type of DLBCL that still has signs of cancer in the blood after initial treatment. The goal is to keep the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07507682Recruiting
Can astaxanthin help manage asthma in polluted areas?
This trial tests if a daily supplement called astaxanthin can help people with mild-to-moderate asthma, especially in areas with more air pollution. You would take capsules and track your breathing at home.
London, BarnetAges 18 years+ - NCT07507708Recruiting
Smart insulin system with behavior support for type 1 diabetes
This study tests a smart insulin pump and continuous glucose monitor system that adjusts insulin automatically and uses behavior support to improve blood sugar control. It's for people with type 1 diabetes who have used an approved automated insulin delivery system recently and are willing to use study devices.
Charlottesville, VirginiaAges 18 years+ - NCT07508280Recruiting
Energy-saving vs circuit training for asthma patients
This trial compares two exercise programs to see which helps people with asthma more. You may join if your asthma is mild to moderate and you do not have other serious conditions.
Jhang, Punjab ProvinceAges 30–50 - NCT07508605RecruitingPhase 1/Phase 2
CD19/CD20 CAR/TRuC-T cells for lymphoma that returned or didn't respond
This trial tests a new type of immune cell therapy that targets two markers (CD19 and CD20) on your lymphoma cells. It is for people whose lymphoma came back or didn't respond to previous treatments, including CD19 CAR-T therapy.
Shenzhen, GuangdongAges 18–75 - NCT07509086RecruitingPhase 2
Enhanced CAR-T therapy for relapsed multiple myeloma
This trial tests a new type of immune cell therapy (CAR-T cells boosted with a protein called IL-15) for people with multiple myeloma or plasma cell leukemia that has not responded to standard treatments or has come back. The goal is to see if these enhanced cells can better fight the cancer.
Changchun, JilinAges 18–80 - NCT07509749RecruitingPhase 2
New treatments for severe acute GVHD after stem cell transplant
This trial tests new medications for people who develop severe acute graft-versus-host disease (aGVHD) within 100 days after their first stem cell transplant. The goal is to find safer, more effective ways to control aGVHD and improve recovery.
BeijingAges 14 years+ - NCT07510607RecruitingPhase 2
Metabolic imaging study for multiple sclerosis
This study tests a new imaging method using a special substance called hyperpolarized 13C pyruvate to see how it can help understand multiple sclerosis. You may join if you have relapsing-remitting MS, have not used disease-modifying treatments in the past two years, and are planning to start anti-CD20 therapy.
San Francisco, CaliforniaAges 18 years+ - NCT07513129RecruitingPhase 1
New drug combination for relapsed T-cell blood cancer in teens and young adults
This trial tests a combination of four drugs (venetoclax, dexamethasone, bortezomib, and daratumumab) to treat T-cell acute lymphoblastic leukemia or lymphoma that has come back or stopped responding to prior treatment. The goal is to see if this combination can help patients aged 12–30 achieve remission.
Houston, TexasAges 12–30 - NCT07514052Recruiting
Predicting Response to Selinexor Treatment in Relapsed Multiple Myeloma
This study tests whether doctors can predict which patients with relapsed or hard-to-treat multiple myeloma will respond well to a drug called selinexor. Researchers will collect blood and bone marrow samples to identify markers that help personalize treatment decisions.
Taiyuan, ShanxiAges 18 years+ - NCT07517250Recruiting
Study of Canakinumab for Fever and Joint Disease
This is a study looking back at patients who were already treated with a medicine called canakinumab for familial Mediterranean fever or Still's disease (rare conditions that cause fevers and joint pain). Researchers want to understand how well this medicine worked over time and what happened to patients who took it.
BaselAges 1 year+ - NCT07517575RecruitingPhase 2
Olokizumab for Children with Juvenile Idiopathic Arthritis
This trial tests a new medicine called olokizumab in children and teenagers with juvenile idiopathic arthritis (JIA)—a condition where the immune system causes joint inflammation and pain. The study checks if this drug is safe and effective for children whose arthritis hasn't improved enough with standard treatments.
Kazan'Ages 2–17 - NCT07518446Recruiting
Health Screening for Adults Starting Psychiatric Care
This study checks the physical health of adults beginning treatment for serious mental illnesses like schizophrenia or depression at two Danish clinics. It aims to catch health problems early that people with these conditions often experience.
CopenhagenAges 18 years+ - NCT07519356Recruiting
Registry for blood and lymph node disorders
This study collects information from patients with lymphoproliferative disorders—conditions affecting blood and lymph cells—to help doctors better understand these diseases and improve care. Your medical records and information may be used to support research that could benefit future patients.
Pavia, LombardyAges 18 years+ - NCT07522008Recruiting
Testing a blood-cleaning add-on for dialysis symptom relief
This trial tests whether adding a special blood-filtering device (hemoadsorption) to your regular dialysis treatment can reduce uncomfortable symptoms caused by kidney failure, like fatigue or itching. Researchers will track how you feel over time compared to standard dialysis alone.
Cagliari, ItalyAges 18 years+ - NCT07522905Recruiting
Virtual Movement Therapy for Kids With Leukemia in Remission
This study tests a fun virtual movement program where children who have finished leukemia treatment exercise together with a healthy friend online. The goal is to help improve their physical strength, coordination, and social skills after cancer treatment.
BratislavaAges 5–12 - NCT07523542RecruitingPhase 1/Phase 2
CAR-T Cell Therapy for Treatment-Resistant Lupus
This study tests a new type of immune cell therapy (CAR-T cells) designed to target and reduce the immune cells driving lupus in patients whose disease hasn't responded to standard treatments. Researchers will first identify which specific immune cells are causing your lupus, then engineer your own immune cells to fight them.
Shenzhen, GuangdongAges 18–70 - NCT07523555RecruitingPhase 1/Phase 2
Dual-Target CAR-T Cells for Blood Cancers That Haven't Responded to Treatment
This study tests a new type of cell therapy called CAR-T cells that are designed to target two different proteins on cancer cells. These cells are made from your own immune cells, trained in the lab, and then put back into your body to fight blood cancers that have come back or stopped responding to previous treatments.
Shenzhen, GuangdongAges 18–75 - NCT07523737RecruitingPhase 2
Combination drug trial for relapsed brain lymphoma
This trial tests three drugs together—pomalidomide, an anti-PD-1 antibody, and selinexor—to treat primary central nervous system lymphoma (a blood cancer in the brain) that has returned after previous treatment. The goal is to see if this combination can shrink the cancer and help patients live longer.
Beijing, Beijing MunicipalityAges 18–75 - NCT07524231Recruiting
Laughter Yoga Effects on Health and Well-being
This study tests whether laughter yoga—guided exercises that combine laughter with breathing—can improve health outcomes. Researchers will measure how it affects participants' physical and mental well-being over time.
ElâzığAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.