Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,069 recruiting studies in this area right now.
By phase
- Not applicable3,003
- Phase 21,060
- Phase 1795
- Phase 1/Phase 2443
- Phase 3437
- Phase 4232
- Phase 2/Phase 399
Top conditions
- Multiple Sclerosis331
- Multiple Myeloma329
- Asthma194
- Lymphoma179
- Type 1 Diabetes132
- Rheumatoid Arthritis131
- Atopic Dermatitis121
- Systemic Lupus Erythematosus120
- Acute Lymphoblastic Leukemia118
- HIV Infections105
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Mantle Cell Lymphoma63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- City of Hope Medical Center50
- Mayo Clinic50
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California498
- Maryland198
- Alabama178
- Florida152
- Arizona150
- Massachusetts116
- New York115
- Texas112
- Illinois86
- Colorado81
Recruiting studies6,069 total
- NCT01353547Recruiting
Study genes and environment in multiple sclerosis risk
This study looks at how genes and life exposures may relate to developing multiple sclerosis (MS) or to MS itself. You may be invited if you have a specific connection to MS or certain past immune-related treatments.
Bethesda, MarylandAges 18 years+ - NCT01853631RecruitingPhase 1
CAR T-cell therapy for CD19-positive B-cell blood cancers
This Phase 1 study tests a personalized form of immune therapy called CAR T cells that are designed to recognize CD19, a marker on certain B-cell cancers. It may help people with difficult-to-treat (recurrent or relapsed) B-cell lymphoma or leukemia (ALL/CLL).
Houston, TexasAges Up to 75 years - NCT01832324Enrolling by invitation
Study the causes of food allergy using blood samples
This study looks for the biological reasons behind food allergies by collecting a small amount of blood. It may help scientists better understand different types of food allergy and eventually improve diagnosis or treatments.
Philadelphia, PennsylvaniaAges 1 month–65 years - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT01890486Recruiting
Collecting information from people having a stem cell transplant
This study aims to collect, store, and share data from patients who are receiving standard intensive treatment and a stem cell transplant from either their own cells or a donor. It may help improve how future patients are treated by building a reliable record of outcomes and care patterns.
Winston-Salem, North CarolinaAges 18–120 - NCT00571389Recruiting
Collecting blood cells from people with cancer or COVID-19
This study collects blood cells using a special blood-draw procedure called leukapheresis (for some participants) and other samples. It aims to better understand cancer and immune-related cells, which may help researchers design or improve future treatments.
Huntersville, North CarolinaAges 5 years+ - NCT00501826RecruitingPhase 2
Check nelarabine plus chemotherapy for T-cell blood cancers
This trial tests a combination of chemotherapy with nelarabine in people with T-cell acute lymphoblastic leukemia (ALL) or T-cell lymphoblastic lymphoma. It may help by improving remission in newly diagnosed or certain previously treated patients whose disease did not respond after one initial treatment.
Houston, TexasAges Any age - NCT00198068Recruiting
Study pregnancy outcomes in lupus and antiphospholipid syndrome
This study looks for factors that may predict how pregnancy turns out in people with lupus (SLE) and/or antiphospholipid syndrome (APS). It may help doctors better understand what to monitor in early pregnancy to support healthier outcomes.
Chicago, IllinoisAges 18–45 - NCT00131014Recruiting
Building a family tumor and genetics bank for blood cancers
This study collects and stores tumor/tissue information and family medical history from people with certain blood cancers. It aims to help researchers understand why these illnesses may run in families and use genetic clues for future research.
Boston, MassachusettsAges 18 years+ - NCT00470327Recruiting
Study of how interstitial lung disease naturally changes
This study looks at how interstitial lung disease (lung scarring) typically progresses over time. It may help researchers understand what to expect and what changes to watch for.
Chicago, IllinoisAges 18 years+ - NCT00341744Recruiting
Access to learning for children with low vision
This trial aims to help children with low vision access the visual environment needed for school, especially for learning to read. It may help by supporting how vision is used for reading in everyday school activities.
Nashville, TennesseeAges 3–21 - NCT00900497Enrolling by invitationPhase 1/Phase 2
Donor white blood cells to treat solid tumors
This Phase 1/2 study tests whether donated white blood cells (granulocytes) from healthy donors can help treat solid cancers that cannot be cured or have stopped responding to standard treatments. The goal is to see safety first, and then whether the treatment can shrink or control tumors.
Boynton Beach, FloridaAges 18 years+ - NCT01163578Recruiting
Using test results to improve outcomes after organ or marrow transplant
This study looks at “biomarkers,” which are measurable lab signals, in people who have had an organ or bone marrow transplant. The goal is to use these test results to better predict and improve transplant outcomes.
Pittsburgh, PennsylvaniaAges Any age - NCT00411983Recruiting
Long-term follow-up for people in the HIV-NAT studies
This study checks in with people who have joined HIV-NAT research in the past or are joining it now, to learn how their HIV and treatment outcomes look over time. It may help improve future care and research for people living with HIV.
BangkokAges 18 years+ - NCT01244802Enrolling by invitation
Study of immune memory after yellow fever vaccination
This study looks at how your immune system “remembers” the yellow fever vaccine over time. It may help researchers understand long-term immune protection and how it varies between people.
Decatur, GeorgiaAges 18 years+ - NCT01137825Recruiting
Older patient cancer registry for a health check
This study is a registry that collects information from older adults who may be dealing with cancer. It includes a short health and function check to help doctors understand needs and guide care, even for people who turn out not to have cancer.
Boone, North CarolinaAges 65 years+ - NCT00482794Recruiting
Study genetic risk factors for antiphospholipid antibody syndrome
This study looks at genetic (inherited) risk factors in people who have antiphospholipid antibodies and related symptoms. Your results may help researchers better predict who is at risk and improve care for antiphospholipid antibody syndrome.
Durham, North CarolinaAges Any age - NCT00756769Recruiting
Gullah community study for lupus symptoms and risk factors
This study looks at lupus in people from the Gullah community in South Carolina, including people with lupus and healthy comparison participants. It may help researchers better understand who is at risk and how lupus shows up in this community.
Charleston, South CarolinaAges 2 years+ - NCT00704626Enrolling by invitation
Blood antibody tests in autoimmune brain and nerve diseases
This study looks at blood “auto-antibodies,” which are immune proteins that may attack the body, in people with certain brain and nerve conditions. It may help researchers better understand these diseases and how the immune system is involved.
Sacramento, CaliforniaAges 18 years+ - NCT00412594RecruitingPhase 2
Cladribine plus rituximab for hairy cell leukemia
This trial tests whether a combination of two medicines—cladribine and rituximab—can treat hairy cell leukemia. You might be able to join if your leukemia is confirmed and you meet timing, blood test, and health requirements.
Houston, TexasAges 18 years+ - NCT01209000Recruiting
Study for children with new kidney protein loss
This study is for children (and some newly diagnosed patients) who have nephrotic syndrome—kidneys leaking a lot of protein. It aims to better understand the kidney condition (sometimes using biopsy) and support future care decisions.
Los Angeles, CaliforniaAges Up to 80 years - NCT00187512Recruiting
Study of how HIV treatment changes outcomes over time
This is an observational study (not a new drug) that tracks how living with HIV can change over time in different treatment situations. It may help researchers understand long-term effects of the modern “protease inhibitor era” and improve future care.
San Francisco, CaliforniaAges 18 years+ - NCT00315380Recruiting
Study following people with eosinophilic granulomatosis with polyangiitis
This study looks at the health course of people who have eosinophilic granulomatosis with polyangiitis, a rare inflammatory condition. Your participation may help researchers better understand how the illness changes over time.
San Diego, CaliforniaAges Any age - NCT00186147Enrolling by invitation
Bone marrow grafting for leukemia and lymphoma
This study involves bone marrow cell grafting for people affected by leukemia or lymphoma. You may be eligible if you are a transplant recipient or a donor and you freely choose to take part.
Stanford, CaliforniaAges 18–70
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,069 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,273 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.