Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT07661667Enrolling by invitation
Laser therapy for nerve damage from anti-MAG antibodies
This study tests whether a specific type of light therapy (photobiomodulation) can improve symptoms of nerve damage (peripheral neuropathy) caused by anti-MAG antibodies. If you have this condition, this trial might offer a new way to manage your symptoms.
QuimperAges 18 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07582653Enrolling by invitation
Testing a digital health tool for stable multiple sclerosis
This study tests a new digital tool designed to help monitor and manage multiple sclerosis (MS). You'll use the tool as part of regular check-ins, and researchers will see if it helps track your condition better over time.
Exeter, DevonAges 18–80 - NCT07567989Enrolling by invitation
Home Exercise and Brain Stimulation for MS Fatigue
This study tests whether doing exercises at home combined with a non-invasive brain stimulation technique (gentle electrical stimulation on your scalp) can reduce the exhaustion and tiredness that comes with multiple sclerosis. The goal is to see if this combination helps you feel less fatigued and improves your ability to stay active.
A Coruña, A CoruñaAges 18–75 - NCT07564921Enrolling by invitation
Nutrition and Muscle Strength in Multiple Sclerosis With Swallowing Difficulty
This study looks at how nutritional status and muscle function relate to each other in people with multiple sclerosis who have difficulty swallowing. Understanding this connection may help doctors better support patients with MS who struggle with eating and drinking.
Gaziantep, şehitkamilAges 18–65 - NCT07553312Enrolling by invitation
Community Support Program for Women Living With HIV
This study tests whether connecting women with HIV/AIDS between their hospital clinic and community resources improves their health and well-being. The program aims to bridge the gap between medical care and community support to help you stay healthier.
Baltimore, MarylandAges 18 years+ - NCT07544290Enrolling by invitation
Autoimmune Hyperthyroidism Study in Young Children
This study looks at children with autoimmune hyperthyroidism (an overactive thyroid caused by the immune system attacking the thyroid gland). Researchers want to understand this condition better in children before puberty to help improve care.
Milan, ItalyAges 2–18 - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07517536Enrolling by invitation
CHT105 treatment for hard-to-treat lupus kidney disease
This study tests a new medicine called CHT105 for lupus patients whose kidney disease hasn't improved with standard treatments. The medicine targets specific immune cells that may be driving the kidney damage.
Nanjing, JiangsuAges 18–65 - NCT07517510Enrolling by invitationPhase 2
HVA treatment for newly diagnosed mixed-phenotype acute leukemia
This study tests a drug called HVA to treat mixed-phenotype acute leukemia (MPAL), a rare blood cancer that has features of both lymphoblastic and myeloid leukemias. You may qualify if you've just been diagnosed and haven't started strong anti-cancer treatment yet.
Guangzhou, GuangdongAges 18 years+ - NCT07515430Enrolling by invitation
Gut Bacteria and Cancer Symptoms in Children With Leukemia
This study looks at how the bacteria living in your child's gut may affect cancer-related symptoms (like nausea, fatigue, or pain) during leukemia treatment. Researchers will collect stool samples and track symptoms to understand this connection better.
Guangzhou, GuangdongAges 5–18 - NCT07503197Enrolling by invitation
Cholesterol cream for child eczema
This trial tests a 2% cholesterol cream to see if it helps children with mild to moderate eczema on their inner elbows. It's designed for Thai children aged 7 to 17 who are not using strong immune-suppressing drugs.
BangkokAges 7–17 - NCT07503028Enrolling by invitationEarly Phase 1
Stem cell therapy for severe low blood sugar in diabetes
This trial tests a new treatment made from stem cells that may help people with diabetes who have dangerous low blood sugar episodes. It aims to see if these cells can replace some of the pancreas function and prevent severe hypoglycemia.
Hefei, AnhuiAges 18–70 - NCT07501624Enrolling by invitation
Pharmacist-led tobacco treatment for HIV patients
This study works with pharmacists at six Ryan White HIV clinics to help people with HIV quit smoking or using tobacco. If you have HIV, are 21 or older, and have already met with a pharmacist about tobacco, you may be able to join.
Charleston, South CarolinaAges 21 years+ - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT07494188Enrolling by invitation
Sleep screening for teens with type 1 diabetes
This study screens teenagers with type 1 diabetes for sleep problems and offers support to improve sleep, which may help with blood sugar control.
Aurora, ColoradoAges 11–17 - NCT07474051Enrolling by invitation
Long-term follow-up for CAR-T cell therapy patients
This study tracks people who received a specific CAR-T cell therapy made by AvenCell. The goal is to monitor their health over time to better understand long-term effects.
BerlinAges Any age - NCT07462338Enrolling by invitation
Walking test reliability in multiple sclerosis patients
This study checks how reliable a simple walking test (Timed Up and Go) is for people with multiple sclerosis, especially when they do another task at the same time. It aims to improve how doctors measure walking ability.
Gaziantep, GaziantepAges 18–65 - NCT07431658Enrolling by invitation
Diet and stress effects on omalizumab response in chronic hives
This study looks at how diet and oxidative stress (a type of cell damage) affect the severity of chronic hives and how well patients respond to the medication omalizumab (Xolair). It may help find ways to improve treatment by understanding these factors.
IstanbulAges 18–65 - NCT07410403Enrolling by invitation
AI study to predict genetic changes in myeloma cells
This trial uses artificial intelligence to look at individual myeloma cells under a microscope to predict genetic abnormalities (FISH results). It may help doctors understand your myeloma better without waiting for a separate FISH test.
Wuhan, HubeiAges Any age - NCT07395232RecruitingPhase 3
Testing a new drug for allergic eye disease (AKC)
This study tests a new medication called DFL24498 for people with atopic keratoconjunctivitis (AKC), a severe allergic eye condition. The goal is to see if it reduces itching, discomfort, and eye redness safely.
Jacksonville, FloridaAges 18–65 - NCT07394361Enrolling by invitation
Clinical Pilates for women with lupus: fatigue and quality of life
This study tests whether clinical Pilates training can help reduce fatigue, improve mood, sleep, and overall quality of life in women with systemic lupus erythematosus. If you have low disease activity and are not already exercising regularly, you may be able to participate.
Adana, SaricamAges 18–55 - NCT07386587Enrolling by invitationPhase 3
Methotrexate plus etanercept for juvenile arthritis
This study compares methotrexate alone versus methotrexate combined with etanercept to see which works better for children with polyarticular juvenile idiopathic arthritis. The goal is to help children achieve low disease activity quickly.
Lahore, Punjab ProvinceAges 2–16
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.