Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT05694637Enrolling by invitationPhase 4
Support to help daily smokers with HIV stay abstinent
This Phase 4 study tests a smoking-quit support approach (reinforcement and coaching) to help people with HIV stop smoking and stay smoke-free. It may help improve smoking abstinence while you continue HIV care.
Francistown, Central DistrictAges 18 years+ - NCT05705024RecruitingPhase 2
Eye drops/treatment to heal stubborn cornea surface damage
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
Chicago, IllinoisAges 18 years+ - NCT05692011Recruiting
Testing a blood-filter treatment in children with early sepsis
This trial looks at whether a blood-filter treatment (called “AN69ST Verse PS” using a hemofilter) can help children with early, serious sepsis and poor circulation or organ problems. It may help stabilize the body faster, but eligibility is limited to certain sepsis situations and recent timing.
Shanghai, Shanghai MunicipalityAges 4 weeks–28 years - NCT05708508RecruitingPhase 3
Immune-guided vs universal medicine to prevent CMV after kidney transplant
This study compares two strategies to prevent a viral infection called CMV after kidney transplant. It tests whether an “immune-guided” approach (using your immune test results) can prevent CMV as well as or better than giving preventive antiviral medicine to everyone.
RouenAges 18–75 - NCT05691348Recruiting
Same-day surgery for uncomplicated acute appendicitis
This trial studies whether removing an uncomplicated appendix in one day (without an overnight hospital stay) is safe and practical. It may help patients recover faster at home, if they meet the trial’s safety requirements.
Nice, Alpes MaritimesAges 15–74 - NCT05206500RecruitingPhase 4
Test whether urine genetic testing changes care
This study looks at whether next-generation DNA testing from your urine can help doctors make better decisions about your treatment. You may be asked to return for follow-up visits so researchers can compare outcomes over time.
Winston-Salem, North CarolinaAges 18–80 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT05660980RecruitingPhase 1/Phase 2
Oral and monthly shots for HIV control in children
This trial studies whether a child can safely move from HIV medicine taken by mouth to long-acting monthly injections. It looks at keeping HIV levels suppressed (very low) and monitoring side effects and safety over time.
Atlanta, GeorgiaAges 2–11 - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+ - NCT05639647RecruitingPhase 2
Aztreonam plus avibactam for serious gram-negative infections
This trial compares two IV antibiotics (aztreonam and avibactam) against the best available treatment for serious gram-negative infections. It may help people who are hospitalized and need IV antibiotics, especially when the infection is caused by certain gram-negative bacteria.
San Diego, CaliforniaAges 9 months–17 years - NCT05645107RecruitingPhase 3
XEMBIFY plus usual care to prevent infections
This Phase 3 study tests whether XEMBIFY (an immune protein therapy) plus standard medical treatment can better prevent serious or repeated infections. It is for people with certain cancers of blood/immune systems who are already having trouble with infections.
Bullhead City, ArizonaAges 18 years+ - NCT05655182RecruitingPhase 1/Phase 2
RSV vaccine study for infants and toddlers who may be at risk
This Phase 1/2 study tests an RSV vaccine (BLB-201) in infants and young children. It aims to see how the vaccine works and how safe it is, including in children who already have RSV antibodies or not.
La Mesa, CaliforniaAges 6 months–5 years - NCT05661032Recruiting
Testing new ways to identify respiratory viruses
This study tests “new technologies” to identify what virus is causing a respiratory illness, using samples taken from inside your nose. It may help doctors get faster, more accurate answers about the cause of your symptoms.
Portsmouth, HampshireAges Any age - NCT05639465Recruiting
Prevent mental health symptoms in kids after disasters
This study tests an intervention to help children who were affected by the COVID-19 pandemic and another major disaster avoid later mental health symptoms. It may help families by offering support before problems get worse.
Bradenton, FloridaAges 8–14 - NCT05640336Enrolling by invitation
Antibiotics for early knee or hip joint infections after surgery
This study compares two antibiotic plans for acute (early) infections around an artificial knee or hip, using a procedure to clean the joint and try to keep the implant. It may help find the best approach to control infection and then prevent it from coming back with longer-term antibiotic treatment.
Jacksonville, FloridaAges 18 years+ - NCT05668026RecruitingPhase 1/Phase 2
Venetoclax to shrink HIV reservoir in people on stable ART
This Phase 1/2 study tests whether venetoclax can help reduce the “HIV reservoir,” which is a hidden group of HIV-infected cells, while you stay on your usual HIV treatment. It also looks at whether the drug helps these infected cells die off in a controlled, safe way.
Melbourne, MelbourneAges 18–65 - NCT05656105RecruitingEarly Phase 1
PET scan study of brain inflammation after COVID
This early-phase study uses a special PET scan to look for signs of brain inflammation in people with ongoing (long-term) nervous system symptoms after COVID-19. It may help researchers understand what is driving symptoms and whether this imaging approach can detect inflammation.
Birmingham, AlabamaAges 18–65 - NCT05639933RecruitingPhase 2
Topical cream for EGFR inhibitor skin rash in cancer patients
This Phase 2 study tests a topical cream (HT-001) to treat skin rashes caused by EGFR inhibitors. It aims to see whether the cream is safe and can reduce rash symptoms and discomfort.
Irvine, CaliforniaAges 18 years+ - NCT05642715Recruiting
HIV smoking reduction program with varenicline and online support
This study tests a harm-reduction approach to help people with HIV smoke fewer cigarettes and quit if they want, using an online tobacco program and varenicline (a quit-smoking medicine). You may be placed in one of two different study groups to compare how well the approaches work.
The Bronx, New YorkAges 40–79 - NCT05660148Recruiting
HIV study on resentment, forgiveness, and quality of life
This study looks at how feelings like resentment and the ability to forgive relate to quality of life in people living with HIV. You may be asked to participate in questionnaires and/or follow-up that can be done by phone or video.
AmiensAges 18 years+ - NCT05672927RecruitingPhase 4
Comparing HPV vaccine schedules: 2 doses vs 3 doses
This study compares how well your immune system responds to an HPV vaccine given as either 2 doses or 3 doses in people ages 27–45 who have never had the HPV vaccine. It may help improve HPV prevention strategies and guide the best dose schedule for adults.
Galveston, TexasAges 27–45 - NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05653232Recruiting
Preventing hepatitis C in kidney transplant recipients using antiviral pills
This study tests antiviral medicine given around the time of a kidney transplant to prevent hepatitis C infection when the donor has hepatitis C. It may help uninfected recipients stay hepatitis C–free after receiving the kidney.
La Jolla, CaliforniaAges 18 years+ - NCT05648448RecruitingPhase 2
Early flu antiviral trial for adults with confirmed influenza
This Phase 2 study compares antiviral medicines in adults who have early, flu-like symptoms and test positive for influenza. It aims to see which antiviral treatment works best and is safe for people treated soon after symptoms start.
Minas GeraisAges 18–60
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.