Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT05406037Recruiting
Testing blood and tissue markers for invasive mucormycosis
This study looks for specific lab “biomarkers” in people with mucormycosis, a serious fungal infection. It compares results with people who have higher infection risk but no active infection, to help doctors diagnose and track this illness more accurately.
Lille, Hauts-de-FranceAges 3–64 - NCT05384145Recruiting
Improve HIV testing and follow-up in Alabama clinics
This trial is testing a “whole-people” plan to help more people get HIV tested, get connected to care, and stay on treatment. It is mainly for healthcare and community staff in specific Alabama counties.
Birmingham, AlabamaAges 13 years+ - NCT05388773RecruitingPhase 2
Surgery then lower-dose radiation for p16+ throat cancer
This Phase 2 study tests whether removing the tumor through the mouth, followed by a reduced course of radiation, can control HPV-related (p16+) oropharynx throat cancer. It may help reduce treatment intensity after surgery, while still aiming to keep the cancer from coming back.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05413122RecruitingPhase 2/Phase 3
Smoking quit support for adults living with HIV in South Africa
This trial tests smoking-cessation interventions to help people living with HIV quit smoking or smoke less. You may be eligible if you smoke, are actively engaged in HIV treatment, and can follow the study for about a year.
Soweto, GautengAges 18 years+ - NCT05373758Recruiting
Help for people whose HIV treatment is not working
This trial tests different ways to manage “virologic failure,” meaning HIV viral load stays high while taking TLD (a common HIV medicine combination). It may help people better control the virus and improve treatment results, especially in parts of sub-Saharan Africa.
DurbanAges 15 years+ - NCT05390424Recruiting
Test dried blood spots for hepatitis and HIV
This study checks blood from a simple dried blood spot to screen for hepatitis B, hepatitis C, and HIV. It may help find infections early, which can allow earlier treatment.
AvranchesAges 18 years+ - NCT05350774Enrolling by invitationPhase 2
IV immunotherapy for lingering neurologic effects after COVID-19
This Phase 2 trial tests whether intravenous immunotherapy (IVIG) can improve ongoing neurologic symptoms after a mild-to-moderate COVID-19 illness. It targets people with persistent symptoms such as brain fog, fatigue, trouble thinking, dizziness when standing, and balance or other neurologic problems.
Bethesda, MarylandAges 18–100 - NCT05208710RecruitingEarly Phase 1
Study new HPV vaccine in healthy adults
This early study tests a new HPV (human papillomavirus) vaccine to see if it can safely trigger an immune response in healthy adults. It’s for people who have not had an HPV vaccine before and can follow study vaccination and pregnancy-prevention rules.
HeidelbergAges 18–45 - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT05319353RecruitingPhase 3
Maribavir for kids with CMV after transplant
This Phase 3 trial tests maribavir (an anti-CMV medicine) in children and teens who get CMV infection after a stem cell or solid organ transplant. It aims to see whether the drug is safe and well-tolerated, and whether it can reduce the virus in the body.
Wilmington, DelawareAges Up to 17 years - NCT05350813Recruiting
Using procalcitonin to stop antibiotics earlier safely
This study tests whether a blood test called procalcitonin can help doctors stop intravenous antibiotics earlier in young hospitalized children when an infection seems likely. The goal is to reduce unnecessary antibiotic exposure without missing serious infections.
AmiensAges 3 days–17 years - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT05352061Enrolling by invitation
HIV support program for people with mental health and life challenges
This study looks at how an HIV treatment and prevention program can be improved for people who have HIV plus psychosocial challenges, especially when HIV is not well controlled. You may be able to join if your HIV is recent and higher than target, and you fit one of the specific participant groups.
Miami, FloridaAges 18 years+ - NCT05332444RecruitingPhase 4
Check if stomach-bacteria testing improves rescue treatment for H. pylori
This study compares two ways to treat Helicobacter pylori (H. pylori) infection that didn’t go away with prior therapy. One approach uses test results to guide which medicines to use, and the other uses standard (“empiric”) treatment. The goal is to see which works better and more safely as a rescue plan.
TaipeiAges 20 years+ - NCT05314426Enrolling by invitation
Biobank for people using phage therapy
This study collects and stores samples (a “biobank”) from adults who plan to receive or have already received phage therapy. It helps researchers better understand how phage therapy works and can support future treatment research.
Rochester, MinnesotaAges 18 years+ - NCT05317247Recruiting
Cough sound test to quickly triage possible tuberculosis
This trial checks whether listening to your cough on an audio recording can help triage—meaning sort—people who may have tuberculosis (TB). If you have had a cough for at least two weeks, the study may help doctors decide who needs further TB testing.
Cape Town, Western CapeAges 12 years+ - NCT05359991Recruiting
Exercise study in children and teens with lung or blood conditions
This study tests how safe and effective a structured exercise program is for children and teens. It also compares results between children with sickle cell disease, cystic fibrosis, and healthy peers (and some teens after COVID-19 infection).
Irvine, CaliforniaAges 10–17 - NCT05334004RecruitingPhase 1
Lopinavir/ritonavir for high-grade anal disease in adults
This early-phase study (Phase 1) tests how safe and tolerable the medicine lopinavir/ritonavir is for adults with HIV and biopsy-confirmed high-grade anal dysplasia. It may help find a possible treatment option for people at higher risk, while also checking for side effects and whether the study plan can be followed.
Madison, WisconsinAges 18 years+ - NCT05325008RecruitingPhase 3
IVIG treatment for BK virus after kidney transplant
This Phase 3 trial tests IVIG (an antibody medicine given through a vein) to treat BK virus infection after kidney or pancreas-kidney transplant. It may help lower the BK virus in the blood and protect the transplanted kidney.
Canberra, Australian Capital TerritoryAges 2 years+ - NCT05320835Recruiting
Talk-based overdose prevention for people using opioids
This trial tests an overdose prevention approach for people who have used opioids recently. It aims to help reduce the risk of overdose by offering a structured prevention intervention.
Baltimore, MarylandAges 18 years+ - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05332899RecruitingPhase 1
Flu challenge study in healthy adults to test an investigational approach
This Phase 1 study tests an investigational influenza (flu) approach in a carefully selected group of healthy adults. It may help researchers understand how the flu challenge works and how well the treatment performs and is tolerated.
Atlanta, GeorgiaAges 18–49 - NCT05336851Recruiting
Emergency breathing test study for sudden lung infections
This trial tests an emergency breathing-related approach for adults with a sudden, community-acquired respiratory infection. It may help doctors quickly sort out what’s going on and guide early care.
Hong KongAges 18–100 - NCT05330923Recruiting
HIV and fatty liver check-in study with ultrasound follow-up
This study follows people with HIV who also have fatty liver disease and checks their health over time. It may help by improving monitoring and care planning, especially using ultrasound scans and regular follow-up.
Beijing, Beijing MunicipalityAges Any age
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.