Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT05041907RecruitingPhase 2
Testing an antiviral’s effects in early COVID-19
This trial looks at how well an antiviral works in the body when started early in people with COVID-19 symptoms. You may be able to join if you’re an otherwise healthy adult with confirmed infection and symptoms for less than 4 days.
Minas GeraisAges 18–60 - NCT05022862Recruiting
Check how incentives and vDOT help latent TB treatment
This trial studies whether reminder-based “vDOT” and small economic incentives can help people complete treatment for latent (sleeping) tuberculosis. If you have latent TB and are starting a standard medicine plan, it may help you stay on track and finish safely.
Baltimore, MarylandAges 18 years+ - NCT05000723Recruiting
Follow-up for hip joint infection after joint replacement
This study checks what happens over the long term for people who had an infection around a replaced (prosthetic) hip. It mainly helps doctors understand recovery and long-term outcomes after treatment.
LeuvenAges 18 years+ - NCT05019495Recruiting
Study to improve quit-smoking support for people with HIV
This trial tests ways to deliver tobacco-quit treatment more effectively for people living with HIV. You may help researchers compare different quit-support approaches to see what works best.
Charleston, South CarolinaAges 21 years+ - NCT05044962Recruiting
Study birth control timing in HIV, using blood tests
This study looks at how well HIV treatment (ART) and a hormonal birth control method (DMPA shot or implant) work together, using small blood samples. It may help ensure safer, more effective HIV care and contraception for young women.
Eldoret, KenyaAges 15–24 - NCT04959734Recruiting
Study of COVID-19 effects on emergency visits for infant lung infections
This study looks at how the COVID-19 era changed emergency department visits for young children with breathing problems, such as bronchiolitis or first-time viral wheeze. It may help doctors understand trends in these illnesses and plan better care during outbreaks.
LeicesterAges birth–2 years - NCT04949464Recruiting
Smoking quit coaching plus lung scans for people with HIV
This study tests a behavior-change program to help people with HIV quit smoking, along with routine low-dose lung CT scans to find warning signs early. It’s a feasibility study, meaning the main goal is to see if the approach is practical and acceptable, and if people can follow through.
La Jolla, CaliforniaAges 45–80 - NCT04941274RecruitingPhase 1/Phase 2
Abemaciclib for Kaposi sarcoma in people with or without HIV
This Phase 1/2 study tests the medicine abemaciclib to shrink Kaposi sarcoma (KS) lesions and control the disease. It includes both people with HIV and people without HIV, and may help when KS has not responded well to prior treatment or when certain KS stages are present.
Bethesda, MarylandAges 18–99 - NCT04984772Enrolling by invitation
HIV and hepatitis B coinfection follow-up study in Europe
This study follows people who have both HIV and hepatitis B over time to better understand how the infection responds after starting treatment. Your information (and sometimes stored blood samples) helps researchers track changes from the start of therapy to about 2 years later.
Ages 16 years+ - NCT04956445Recruiting
Donate blood and mucus samples to study virus treatments
This study collects samples from people who currently have, recently had, or may have been exposed to common respiratory viruses. The goal is to use these samples to develop and test future countermeasures (like treatments) against COVID-19 and other viruses.
New Orleans, LouisianaAges 6 months–120 years - NCT04987840Enrolling by invitation
Hospital program to reduce unnecessary lung culture tests in kids
This trial studies a hospital quality-improvement program that aims to use fewer “respiratory culture” tests in pediatric intensive care units (PICUs). It may help reduce unnecessary testing while maintaining good care for critically ill children.
Baltimore, MarylandAges Any age - NCT04955210Recruiting
Study of data sharing in children with severe infections
This trial builds a shared medical data system to better understand severe pneumonia and sepsis in children. Your participation helps clinicians and researchers learn from many cases to improve future care.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04953130RecruitingPhase 4
HPV vaccine for boys in Tanzania
This trial studies whether giving one dose of the HPV vaccine to boys, in addition to vaccinating girls, helps protect more people from HPV-related cancers. Boys aged 14-18 who live in certain communities in Tanzania may be able to take part.
MwanzaAges 14–18 - NCT04979728Recruiting
Check whether home blood drops work for HIV monitoring
This study tests whether people with HIV can safely collect small blood samples at home using finger-pricks and devices (“dried blood spots”). It may help make HIV monitoring easier and more convenient while on certain HIV medicines.
Aurora, ColoradoAges 18 years+ - NCT04942886Enrolling by invitation
Preventing hepatitis B reactivation after stem cell transplant
This trial tests whether taking the antiviral medicine entecavir before and after a stem cell transplant can prevent hepatitis B from “waking up” again. It may help protect your liver during a high-risk treatment period.
SeoulAges 19–70 - NCT04961593Recruiting
Studying caspofungin dosing in very ill children
This study looks at how caspofungin works in children who are very sick and in the pediatric intensive care unit. It helps doctors better choose dosing to keep the medicine at the right level.
Shanghai, Shanghai MunicipalityAges 3 months–18 years - NCT04978571Recruiting
Electrical nerve stimulation for long-lasting concussion symptoms
This study tests whether a device that delivers gentle electrical signals to nerves through the skin can help children and teens with concussion symptoms that have lasted at least 3 months. You may be asked to attend clinic visits for the nerve stimulation setup if you meet the safety and scheduling requirements.
Orange, CaliforniaAges 11–18 - NCT04958122RecruitingPhase 3
Antibiotic treatment trial for early syphilis
This Phase 3 study tests whether cefixime can treat primary, secondary, or early latent syphilis. It may help by offering another effective antibiotic option, including for some people who also have HIV (if well controlled).
Los Angeles, CaliforniaAges 18 years+ - NCT04975152RecruitingPhase 1
Cemiplimab before surgery for Merkel cell and skin cancers
This early-phase study tests cemiplimab (an immune therapy that helps your immune system attack cancer) given before surgery. It aims to shrink tumors and improve outcomes for people with Merkel cell cancer or certain locally advanced skin squamous cell cancers (CSCC).
Tampa, FloridaAges 18 years+ - NCT04961580Recruiting
Study of ceftazidime dosing in sick children
This trial measures how ceftazidime (an antibiotic) moves through the body and how it works in children with severe infections in the pediatric intensive care unit. It may help doctors choose safer, more effective dosing for kids.
Shanghai, Shanghai MunicipalityAges 3 months–18 years - NCT04914611Recruiting
Real-world study of chronic hepatitis B care in Australia
This study looks at people who have long-term hepatitis B and how they receive care in Australia. It may help improve understanding of what’s working in real life for patients like you.
Sydney, New South WalesAges 18 years+ - NCT04902443RecruitingPhase 1
Pomalidomide and nivolumab for virus-related cancers
This trial tests two drugs (pomalidomide and nivolumab) in people with cancers caused by viruses. The goal is to see if this combination can shrink or control tumors that haven't responded to standard therapies.
Bethesda, MarylandAges 18–99 - NCT04896606RecruitingPhase 1/Phase 2
Matched donor immune therapy for mild to moderate COVID-19
This early-phase study tests immune cells from a matched family donor (made to target the COVID-19 virus) to see if they can help people with mild-to-moderate COVID-19 who are hospitalized and at higher risk for getting sicker. It aims to check safety first and also look for signs of benefit.
Valhalla, New YorkAges 18–65 - NCT04886284RecruitingPhase 2
Cefazolin plus ertapenem for MSSA bloodstream infection
This Phase 2 study tests whether adding ertapenem to cefazolin can improve treatment of staphylococcus (“S. aureus”) bloodstream infection that is likely methicillin-susceptible (MSSA). It aims to start the right antibiotics quickly, before MRSA status is fully confirmed, using early testing and a treatment plan guided by infectious-disease specialists.
Calgary, AlbertaAges 18–100
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.