Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT04855786Recruiting
Drain lymph fluid to reduce inflammation in septic shock
This study tests whether draining fluid from a chest lymph channel can lower inflammation chemicals (cytokines) in people with septic shock. It’s done using a procedure and aims to see if this helps stabilize the body’s inflammatory response.
Philadelphia, PennsylvaniaAges 18–80 - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT04923828Recruiting
Study drug resistance in very sick children with infections
This trial enrolls children in the pediatric intensive care unit (PICU) who have a severe infection. It aims to better understand germs and drug resistance so future treatments can be more effective.
Shanghai, Shanghai MunicipalityAges 1 month–16 years - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04923958Recruiting
Testing new TB screening and diagnostic tests
This study tests rapid TB screening and lab-style diagnostic methods to see how well they find TB disease and TB that is resistant to rifampin (a key TB drug). It may help doctors diagnose TB faster and more accurately, especially in people at higher risk.
TbilisiAges 12 years+ - NCT04896606RecruitingPhase 1/Phase 2
Matched donor immune therapy for mild to moderate COVID-19
This early-phase study tests immune cells from a matched family donor (made to target the COVID-19 virus) to see if they can help people with mild-to-moderate COVID-19 who are hospitalized and at higher risk for getting sicker. It aims to check safety first and also look for signs of benefit.
Valhalla, New YorkAges 18–65 - NCT04915261RecruitingPhase 4
Lenient versus strict instructions after heart device surgery
This trial compares two styles of “post-surgery instructions” after implantation of a new heart device lead. It may help determine which approach is better for patients’ recovery and safety after the procedure.
Ottawa, OntarioAges Any age - NCT04103268Recruiting
Study blood tests to understand organ injury in children with sepsis
This study uses special blood testing to learn what is happening in the immune system during sepsis in children and how it may relate to organ injury. Your results may help doctors recognize and treat sepsis earlier and more accurately.
Boston, MassachusettsAges 1 month–17 years - NCT04844801Recruiting
Prevent fast heart rhythms during sepsis shock with rate control drugs
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
ParisAges 18 years+ - NCT04772170Recruiting
Study wearable and symptom monitoring during respiratory virus challenges
This observational study looks for digital health patterns during studies where people are intentionally exposed to a respiratory virus. If you join a respiratory virus challenge at NIH, you may help researchers discover better ways to monitor and understand illness using wearable devices and shared health data.
Bethesda, MarylandAges 18–65 - NCT04799288RecruitingPhase 1/Phase 2
Teriflunomide for HTLV-1 spinal cord stiffness and weakness
This early-phase trial tests whether teriflunomide can help people with HTLV-1 associated myelopathy (HAM) or tropical spastic paraparesis (TSP). It also checks safety and how well the treatment can be followed over time.
Bethesda, MarylandAges 18–120 - NCT04793152Recruiting
Tested vancomycin dosing for serious MRSA using different lab targets
This trial compares two ways of dosing vancomycin (an antibiotic) for serious MRSA infections by using different blood test targets. The goal is to see if the newer approach works at least as well as the standard one, while keeping patients safe.
Hamilton, OntarioAges 18 years+ - NCT04801862Recruiting
Understanding Clostridioides difficile infection over time
This study follows people who have a Clostridioides difficile infection to learn more about how the infection progresses and affects patients. By tracking symptoms and outcomes, researchers hope to improve future care.
Alicante, AlicanteAges 18 years+ - NCT04807660Recruiting
Testing germs in children with ear drainage
This study checks what germs are causing ear drainage (“otorrhea”) in children. The results may help doctors choose the right treatment.
CréteilAges 3 months–15 years - NCT04851015RecruitingPhase 3
Low-dose TMP-SMX for Pneumocystis pneumonia (PCP)
This Phase 3 study tests whether low-dose trimethoprim-sulfamethoxazole (also called TMP-SMX) can treat Pneumocystis pneumonia (PCP) in people with weakened immune systems. It may help improve treatment while reducing side effects compared with standard dosing.
Montreal, QuebecAges 18–100 - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04794595Recruiting
Compare outcomes in children with and without CBP during sepsis
This study looks at children with sepsis to see how outcomes differ between those who receive a specific blood-cleansing treatment (CBP) and those who do not. Results may help clinicians choose treatments that lead to better recovery in sick children.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04814693Enrolling by invitation
Endoscopic removal of pancreatic dead tissue: two technique options
This trial compares two ways of clearing “walled-off” dead tissue in the pancreas using an endoscope—one is standard tools, the other is the EndoRotor® system. It aims to see which approach is safer and works better after you’ve already had drainage.
Birmingham, AlabamaAges 18 years+ - NCT04815096RecruitingPhase 2
PET scan study of immune activity after COVID-19
This Phase 2 study uses a special PET scan to look at how active your immune system is after a recent COVID-19 infection. The goal is to understand what the immune response looks like and whether this imaging approach could help guide care.
San Francisco, CaliforniaAges 18 years+ - NCT04807842Recruiting
Testing ActiGel Plus to treat bacterial vaginosis
This study tests whether ActiGel Plus can treat bacterial vaginosis (BV). It may help by improving symptoms and vaginal health after BV is confirmed.
HamburgAges 18 years+ - NCT04821154Recruiting
Testing outcomes after revision knee replacement with a Persona system
This study looks at how well a specific revision knee replacement system (the Persona system) works after earlier knee problems or surgeries. You may be eligible if you need a revision knee and can follow follow-up care instructions; the trial also checks for certain infection, bone, and health-safety factors.
Fayetteville, ArkansasAges 18 years+ - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04704648Recruiting
Surgery for a one-eye surface tumor in people with HIV
This study looks at whether removing a suspected pre-cancer/cancer growth on the surface of the eye can be done safely in people living with HIV. It is a feasibility (safety and practical) study, helping doctors refine the best surgical approach and follow-up.
KampalaAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.