Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,219 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 187
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California167
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,219 total
- NCT03718637RecruitingPhase 4
Bioinductive implant for tennis elbow that therapy didn’t fix
This trial tests a special implant placed in the elbow to improve healing in people with tennis elbow (lateral epicondylitis) when physical therapy and other non-surgical treatments haven’t worked. If you qualify, you may receive the implant to see if it helps reduce pain and improve elbow function.
Detroit, MichiganAges 18 years+ - NCT03736382Recruiting
Study how mild low-oxygen affects sleep apnea and blood pressure
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
Detroit, MichiganAges 18–60 - NCT03742687Recruiting
Testing a shorter, stronger radiation schedule for lung cancer
This trial studies a different way to deliver radiation to people with locally advanced, non-operable non-small cell lung cancer. It may help by aiming to treat the tumor effectively with a different radiation timing and dose pattern.
AarhusAges 18 years+ - NCT03759028RecruitingPhase 4
Study of pain relief after elbow fracture surgery
This trial looks at how well different pain medicines work after surgery for a specific type of broken elbow bone. It may help find a safer, more comfortable pain-control plan while the fracture heals.
Los Angeles, CaliforniaAges 4–12 - NCT03765567RecruitingPhase 4
Antibiotic powder placed in certain emergency open fractures
This study tests whether putting antibiotic powder directly into an open fracture wound in the emergency room can improve care outcomes. It focuses on adults treated shortly after injury.
San Antonio, TexasAges 18–89 - NCT03772548Recruiting
MRI study of brain and spinal cord changes after injury
This study uses MRI scans to look at brain and body changes after a spinal cord injury. It may help researchers understand how the nervous system recovers over time.
ZurichAges 18–75 - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT03790943Recruiting
Health study of heart problems in childhood cancer survivors
This study follows people who had cancer as children to learn about heart-related changes years after treatment. It may help doctors better understand who is at risk and how to monitor the heart in long-term survivors.
Basel, Canton of Basel-CityAges 18 years+ - NCT03796572RecruitingPhase 4
Nerve-block pain relief after a specific elbow bone fracture
This trial studies whether a pain-relief “nerve block” with medicine helps control pain after surgery for a particular type of elbow (humerus) fracture. It may help you feel more comfortable during recovery, compared with standard pain control.
Los Angeles, CaliforniaAges 4–12 - NCT03803787RecruitingPhase 2
Inhaled steroid to prevent lung inflammation during cancer treatment
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Mexico CityAges 18–75 - NCT03819062Recruiting
Stomach–bowel nerve stimulation for long-term constipation
This trial studies a device that stimulates nerves near the lower back (sacrum) to improve bowel function in people with severe constipation that hasn’t responded to standard treatments. It may help if your constipation involves problems coordinating bowel movement and the muscles around the rectum.
Hamilton, OntarioAges 6–70 - NCT03819608Recruiting
Brain stimulation and rehab after mild concussion with PTSD or cognitive issues
This trial studies whether brain stimulation plus targeted brain rehabilitation can improve symptoms after a mild concussion (mTBI). You may be invited if your concussion happened at least 3 months ago and your symptoms are affecting thinking or mood, with or without PTSD.
Chicago, IllinoisAges 18–80 - NCT03858231RecruitingPhase 4
Opioid vs non-opioid pain relief after knee arthroscopy
This study compares opioid pain medicine with non-opioid pain medicine after arthroscopic (keyhole) knee surgery. It aims to see which approach controls pain well while keeping side effects and risks lower.
Fargo, North DakotaAges 18–80 - NCT03867539RecruitingPhase 4
Numbing shot and education to reduce opioids after carpal tunnel surgery
This study tests whether giving a long-lasting numbing injection (Exparel) plus education about pain management can help people avoid taking opioid pain pills after carpal tunnel release surgery. It may help reduce opioid use while still supporting comfort during recovery.
Dayton, OhioAges 18 years+ - NCT03883711Recruiting
Study of treatment and outlook after heart attack
This trial studies how people do after a heart attack (or related heart injury) and may test treatments that could improve outcomes. If you’re an adult and recently had this heart event, you may be able to join after discussing consent.
Bologna, BolognaAges 18 years+ - NCT03896464Recruiting
Quadriceps tendon vs hamstring tendon for ACL surgery in teens
This trial compares using a quadriceps tendon graft versus a hamstring graft during ACL reconstruction in children and teens whose growth plates are still open. It aims to see which graft works better after ACL injury while accounting for ongoing bone growth.
Hamilton, OntarioAges 10–18 - NCT03903510Recruiting
Virtual reality during kids’ cast removal
This trial tests whether virtual reality can help children feel calmer during cast removal after a broken arm or leg. It may make the experience less stressful while the cast is being taken off.
Saint Paul, MinnesotaAges 4–12 - NCT03920033Recruiting
Radiation schedule for prostate cancer PSA relapse after surgery
This trial compares two different radiation schedules to treat prostate cancer that returned based on rising PSA blood tests after prostatectomy (prostate removal). If you qualify, it may help you and your team choose a radiation approach with the goal of controlling PSA relapse.
SeoulAges 20 years+ - NCT03921502Recruiting
ERCP vs ERCP with a stomach drainage procedure comparison
This trial compares two endoscopy approaches to drain a blocked bile duct caused by gallstones. It may help people who can’t safely have standard surgery decide which drainage method works best after an initial ERCP plan fails or is limited.
ValladolidAges 75 years+ - NCT03932838Recruiting
Study of knee ligament reconstruction outcomes after injury
This study looks at how people do after one-time surgery to repair multiple knee ligaments using either donor tissue or their own tissue. It helps doctors better understand what to expect after multiligament knee reconstruction.
Le ChesnayAges 18 years+ - NCT03957343Recruiting
Parkwood Pacing and Planning app for concussion recovery
This study tests a smartphone or tablet app (the Parkwood Pacing and Planning app) that may help people after a mild concussion manage recovery. You may be able to join if you’re an adult, can use the app device, and have a confirmed mild concussion.
London, OntarioAges 18 years+ - NCT03965299Recruiting
Gentle nerve stimulation for new spinal cord injury recovery
This study tests whether stimulation through the skin of the tibial nerve can help people with a new spinal cord injury. It may help improve bladder-related symptoms or nerve signaling after injury, compared with standard care.
Zurich, Canton of ZurichAges 18 years+ - NCT03966716Recruiting
Hip screws or hip replacement for small hip fractures
This study compares two treatments for certain small, stable hip fractures in older adults: using hip screws versus replacing part or all of the hip. It may help find which option works best for healing and returning to movement.
Uppsala, Uppsala CountyAges 75 years+ - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,219 recruiting trauma studies from the U.S. registry right now, out of 5,138 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.