Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT05882253Recruiting
Test MRI-guided biopsy for early prostate cancer detection
This study uses a special MRI-guided (MRI-fusion) needle biopsy to look for early prostate cancer. It may help find concerning areas more accurately before cancer spreads.
La Jolla, CaliforniaAges Any age - NCT06738251RecruitingPhase 3
Study of SHR-A2102 for advanced bladder cancer
This trial tests a new drug, SHR-A2102, against the usual treatments for people with advanced bladder cancer that has spread. It is for those whose cancer has worsened after platinum chemotherapy and immunotherapy.
Beijing, Beijing MunicipalityAges 18–80 - NCT06769997Recruiting
Comparing Optilume and Rezum for enlarged prostate
This study compares two treatments for an enlarged prostate: Optilume (a catheter-based system) and Rezum (water vapor therapy). It's for men with moderate symptoms who haven't tried other treatments before.
Montreal, QuebecAges 18 years+ - NCT06795074RecruitingPhase 4
Comparing coated vs non-coated balloons for recurring urethral stricture
This trial tests if a balloon coated with a drug (paclitaxel) helps prevent the urethra from narrowing again after treatment. It may be an option for people whose stricture has come back after a prior procedure.
GothenburgAges 18 years+ - NCT06803030RecruitingPhase 3
Study of three drugs for ureteral stent discomfort
This trial is testing three different medicines to see if they can reduce common symptoms like pain and frequent urination caused by a ureteral stent placed after kidney stone surgery. If you are between 19 and 80 years old and had a stent placed during ureteroscopy, you may be able to join.
Kathmandu, BagmatiAges 18–80 - NCT06800313RecruitingPhase 1/Phase 2
A study of HLD-0915 for metastatic prostate cancer
This trial tests a new drug called HLD-0915 in men with prostate cancer that has spread. It aims to see how well the drug works and if it's safe.
Colorado Springs, ColoradoAges 18 years+ - NCT06801236RecruitingPhase 1
A new drug for advanced prostate cancer that has stopped responding to treatment
This early-phase trial tests a new study drug called ACE-232 for men with advanced prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It aims to see if the drug is safe and may help slow the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06800963RecruitingPhase 1/Phase 2
A new BCG treatment for bladder cancer that hasn't spread
This trial tests a new form of intravesical (given directly into the bladder) treatment called rMBCG for people with non-muscle invasive bladder cancer who have not had BCG therapy before. It may be an option for those with certain types of early bladder cancer, including carcinoma in situ (CIS) or papillary tumors after removal surgery.
Chandler, ArizonaAges 18–85 - NCT06797518RecruitingPhase 2
Testing iptacopan for IgA nephropathy kidney changes
This study tests if adding iptacopan to standard care can improve kidney health in adults with IgA nephropathy. You may qualify if you have a kidney biopsy confirming IgA nephropathy and your kidney function is stable enough.
Birmingham, AlabamaAges 18–99 - NCT06615102RecruitingPhase 3
Testing if angiotensin II prevents kidney injury after heart surgery
This trial tests whether giving a medicine called angiotensin II during heart surgery can help prevent acute kidney injury (a sudden drop in kidney function). It is for adults having certain types of heart surgery who have a higher risk of kidney problems.
BerlinAges 18 years+ - NCT06802224RecruitingPhase 4
Medication to prevent kidney injury after major surgery
This study compares two medications given during surgery to see which one better protects the kidneys after the procedure. If you are having major non-cardiac surgery that lasts at least 2 hours and you need medication to support your blood pressure, this trial may be a good fit.
San Francisco, CaliforniaAges 18 years+ - NCT06797245Recruiting
App-based treatment for overactive bladder in women
This trial tests a prescription digital app to help women with overactive bladder (OAB) symptoms. It may be a good fit if you are a woman over 22 with bothersome OAB and are willing to use the app instead of other treatments for 8 weeks.
Birmingham, AlabamaAges 22 years+ - NCT06793683Enrolling by invitationEarly Phase 1
Early Botox for bladder control after spinal cord injury
This trial tests if giving Botox injections early (within 20 weeks of injury) into the bladder muscle can help with bladder function and prevent problems. It may help people with recent, severe spinal cord injuries above the T6 level.
Seattle, WashingtonAges 18–65 - NCT06803160Enrolling by invitation
Comparing two surgeries for uterovesical fistula repair
This trial compares two laparoscopic (keyhole) surgery methods to fix a uterovesical fistula, which is an abnormal opening between the bladder and uterus that can happen after C-section or other pelvic surgery. The goal is to see which method works best.
CairoAges Any age - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT06798558RecruitingPhase 2
Lu-PSMA before prostate surgery for high-risk cancer
This trial tests a treatment called Lu-177-PSMA-617 given before surgery for high-risk prostate cancer that has spread only to nearby lymph nodes. It aims to see if this approach helps control the cancer before the prostate is removed.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06798311Recruiting
Bladder symptom help for minority women
This study tests whether a conservative, at-home treatment program can help minority women with bothersome bladder control symptoms. It focuses on simple, non-surgical approaches that you can do at home.
Chicago, IllinoisAges 18 years+ - NCT06795087Recruiting
Medication Use After Genitourinary Cancer Surgery
This study looks at the medications patients take after surgery for bladder, kidney, or prostate cancer. The goal is to understand how these medications are used and help improve recovery.
Charlotte, North CarolinaAges 18 years+ - NCT06799936Recruiting
Helping older adults with kidney disease make treatment choices
This study tests a program that helps older adults with advanced chronic kidney disease talk with their doctors about treatment options, like dialysis, palliative care, or a kidney transplant. It aims to make sure patients' values and preferences are heard in these important decisions.
Hong KongAges 65 years+ - NCT06796985RecruitingPhase 1
Botox for Chronic Pelvic Pain in Women
This study tests whether a Botox injection into the pelvic floor muscles can reduce chronic pelvic pain. It is for women who have had pelvic pain for at least 6 months, with tender muscle knots in the pelvic area.
Miami, FloridaAges 18–75 - NCT06793722Recruiting
Comparing standard and device-based circumcision in children
This study compares standard circumcision with a procedure that uses a special device to see if the device works better. It’s for children having circumcision for medical or religious reasons, and who are otherwise healthy with no genital issues.
AdıyamanAges 6–18 - NCT06794229RecruitingPhase 2
Zanzalintinib plus nivolumab before surgery for advanced kidney cancer
This trial tests two drugs—zanzalintinib and nivolumab—given before surgery to shrink advanced or hard-to-remove kidney tumors. The goal is to make the tumor easier to remove and improve outcomes.
St Louis, MissouriAges 18 years+ - NCT06802978Recruiting
Lipid test in diabetic and non-diabetic kidney patients
This study checks cholesterol and fat levels in the blood of people with chronic kidney disease, comparing those with and without diabetes. It aims to understand how kidney disease affects lipid profiles.
SohagAges 21 years+ - NCT06798909RecruitingPhase 3
CMV prevention in kidney transplant patients
This trial tests two ways to prevent CMV in kidney transplant patients who are at high risk. It compares giving antiviral medicine preemptively (based on regular blood tests) versus giving it as prophylaxis (starting right after transplant). The goal is to see which approach prevents CMV infection better.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.