Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT03844399Recruiting
3D ultrasound imaging during liver or kidney procedures
This study uses a new 3D ultrasound scan while you get standard care for a liver or kidney biopsy or ablation. The goal is to see whether the imaging is clear and useful during these procedures.
London, OntarioAges 18 years+ - NCT06666270RecruitingPhase 1
SYN818 for advanced solid tumors with DNA repair defects
This trial tests a new drug called SYN818 for people with advanced breast, ovarian, prostate, or other solid tumors that have stopped responding to standard treatments. It is designed for patients whose tumors have a specific DNA repair problem (BRCA mutation or other HR pathway deficiency).
Zhengzhou, HenanAges 18 years+ - NCT06642220RecruitingPhase 2
Y-90 radioembolization for kidney cancer
This trial tests a procedure called Y-90 radioembolization for patients with kidney cancer tumors larger than 4 cm who cannot have or choose not to have surgery. The treatment delivers tiny radioactive beads through a blood vessel to the tumor to destroy cancer cells while limiting damage to healthy tissue.
London, OntarioAges 18 years+ - NCT06783348RecruitingPhase 2
Radioactive treatment for advanced kidney cancer
This trial tests a radioactive treatment (called radiopharmaceutical) that targets a protein called PSMA on kidney cancer cells. It is for people with advanced clear cell kidney cancer that has already been treated with immunotherapy and targeted therapy.
CaenAges 18–100 - NCT06788509Enrolling by invitationPhase 1
Continued treatment and safety monitoring after a parent study
This trial allows people who were already getting study treatment in a previous trial to keep receiving it and be monitored for safety. It is designed for those who have not had serious side effects or disease worsening.
Macquarie UniversityAges 18 years+ - NCT06792552RecruitingPhase 1
Study of SIM0505 for advanced solid tumors
This trial tests a new drug called SIM0505 for people with advanced solid tumors that have not responded to standard treatments. The study looks at different cancer types, including ovarian cancer, kidney cancer, uterine cancer, and lung cancer, to see if SIM0505 can help shrink tumors or slow their growth.
Orlando, FloridaAges 18 years+ - NCT06785636RecruitingPhase 1/Phase 2
New drug combination for advanced prostate cancer
This study tests a new drug (pocenbrodib) alone or combined with another hormone therapy (darolutamide) for men with advanced prostate cancer that has spread. It is for those who have already tried Pluvicto and one other hormone therapy, but not yet chemotherapy.
Fountain Valley, CaliforniaAges 18 years+ - NCT06789406Recruiting
Testing a new sacral nerve stimulation device for overactive bladder
This study tests a new version of a sacral nerve stimulation device (Axonics model 5101) for people with overactive bladder. It aims to see if the device is safe and works well to reduce sudden urges and frequent urination.
Chicago, IllinoisAges 18 years+ - NCT06790498Enrolling by invitation
Long-term follow-up after renal cell therapy for kidney disease
This study follows people who previously received an experimental treatment called REACT for chronic kidney disease in earlier clinical trials. Its goal is to monitor their health over time.
Meridian, IdahoAges 30–80 - NCT06787053Recruiting
MRI imaging for oxygen-starved tumors
This study uses MRI scans to find areas of low oxygen in tumors and see if adjusting radiation treatment can help. It is open to adults with bladder, cervix, or prostate cancer who are getting radiation therapy at the Christie NHS Foundation Trust.
ManchesterAges 18 years+ - NCT06786728Enrolling by invitation
Ultrasound-guided fluid removal for kidney recovery in heart-kidney syndrome
This study tests if using ultrasound scans to guide fluid removal helps protect kidney function in people with cardiorenal syndrome type 1, where heart failure suddenly worsens kidney function.
CairoAges 18–65 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06788054Enrolling by invitation
Exercise during dialysis for fitness and survival
This study tests whether adding exercise during your dialysis sessions can improve your physical fitness, body composition, and survival. If you are on hemodialysis and meet the health criteria, you would either exercise while on the machine or receive standard care.
León, GuanajuatoAges 18–50 - NCT06792799RecruitingEarly Phase 1
CAR-NK cells for B-cell autoimmune diseases
This early phase trial tests a new treatment made from immune cells (CAR-NK cells) that target and destroy overactive B cells. It may help people with lupus, certain kidney diseases, or nephrotic syndrome that hasn't responded to standard therapies.
Hangzhou, ZhejiangAges 3 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT05574647Recruiting
Fast prostate MRI and guided biopsy testing for prostate cancer
This study checks whether a faster prostate MRI and image-matching (image-fusion) can better find suspicious spots so doctors can target a biopsy. If you have concerning prostate exam results or PSA blood test results, you may get an MRI and, if something looks suspicious, a biopsy using MRI images.
Southend-on-Sea, EssexAges 18 years+ - NCT06037356Recruiting
Comparing two surgeries for enlarged prostate with urinary retention
This trial compares two surgeries for men with an enlarged prostate who have trouble urinating and need a catheter. It helps find out which procedure works better for getting patients back to normal urination.
Hong KongAges 40 years+ - NCT05992363Recruiting
Comparing stents for malignant ureteral blockage
This trial tests whether using two newer stents (Tandem Polyurethane) works better than the standard single silicone stent for people whose urine tubes are blocked by cancer. The goal is to improve urine flow and relieve discomfort.
Petah TikvaAges 18 years+ - NCT06773806Recruiting
Chlordecone exposure and prostate cancer in Martinique
This trial studies whether exposure to the pesticide chlordecone affects prostate cancer risk in men living in Martinique. It compares men newly diagnosed with prostate cancer to those without cancer.
Fort-de-FranceAges 18–75 - NCT06778863RecruitingPhase 1
A study of CLSP-1025 for adults with certain solid tumors
This trial tests a new drug called CLSP-1025 for people with advanced solid tumors that have a specific change in the p53 gene (R175H). The drug targets this change to help fight the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT06772025Recruiting
Understanding kidney injury after heart surgery with heart-lung machine
This study looks at why some people develop kidney damage after heart surgery that uses a heart-lung machine. It aims to help doctors better predict and prevent this complication.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.