Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,386 recruiting studies in this area right now.
By phase
- Not applicable2,716
- Phase 2569
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4191
- Phase 2/Phase 355
Top conditions
- Prostate Cancer644
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer57
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong33
- Novartis Pharmaceuticals33
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- AstraZeneca28
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California356
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,386 total
- NCT06607991RecruitingPhase 1
Blinatumomab for children with steroid-resistant nephrotic syndrome
This trial tests a drug called blinatumomab for children with a kidney condition that doesn't respond to standard treatments. It aims to see if it can help when other drugs have failed or caused side effects.
Hangzhou, ZhejiangAges 2–17 - NCT06483074RecruitingPhase 2
Empagliflozin to preserve kidney function in new peritoneal dialysis patients
This trial tests whether empagliflozin, a medication originally for diabetes, can help protect the remaining kidney function in people who have just started peritoneal dialysis. If you started dialysis within the last 3 months and still make some urine, this study may be a good fit.
Hong KongAges 18–75 - NCT06711887RecruitingPhase 3
Long-term extension study of ianalumab for lupus nephritis
This study is a follow-up for people with lupus nephritis who already completed a 144-week treatment course with ianalumab in an earlier study. It tests whether continuing or stopping the drug is safe and effective over the long term.
Orchard Park, New YorkAges 18–100 - NCT06705686RecruitingPhase 1
New drug for advanced prostate cancer
This trial tests an experimental drug called (R)-9b for men with a specific type of advanced prostate cancer that has stopped responding to hormone therapy. The goal is to see if this drug can help control the cancer.
Madison, WisconsinAges 18 years+ - NCT06708845RecruitingPhase 1
Zamto-cel cell therapy for autoimmune diseases
This early-phase trial tests a new cell therapy called Zamto-cel for people with lupus (with or without kidney inflammation) or systemic sclerosis (hardening of the skin and internal organs). It is for those whose condition has not improved enough after standard treatments.
Milwaukee, WisconsinAges 18 years+ - NCT06712823RecruitingPhase 2
Long-term safety study of atumelnant for adrenal hyperplasia
This study tests the long-term safety and effectiveness of the study drug atumelnant for people with congenital adrenal hyperplasia. It is for those who have already completed a previous atumelnant study and may benefit from continuing treatment.
Minneapolis, MinnesotaAges 16–74 - NCT06714006RecruitingPhase 1
Testing safety of PYC-003 for ADPKD
This study is testing a new investigational medicine called PYC-003 for people with autosomal dominant polycystic kidney disease (ADPKD). It is one of the first studies in humans, so the main goal is to see if the medicine is safe and tolerable. The study is for people with a specific genetic cause (PKD1 mutation) and with certain kidney imaging types.
Southport, Gold CoastAges 18–65 - NCT06714630Recruiting
Study Learning from Men Treated for Prostate Cancer
This trial looks at long-term results after radiation therapy for prostate cancer. By studying PSA test results and imaging scans from men who were treated at least 10 years ago, researchers hope to learn more about side effects and how well the treatment worked over time.
Edinburgh, LothianAges Any age - NCT06706362RecruitingPhase 4
Antibiotics before Bulkamid for bladder leakage
This study tests whether giving a single dose of antibiotics before a Bulkamid procedure (a gel injection for bladder leakage) helps prevent infections. It is for people with stress urinary incontinence (leakage with coughing or sneezing) who are already planning to have this treatment.
Columbus, OhioAges 18–50 - NCT06705855Recruiting
Predicting kidney injury after heart surgery using skin sensors
This study tests whether a special light-based monitor on your skin (near your kidney and arm) can predict kidney injury after heart surgery. It aims to help doctors protect your kidneys during and after the procedure.
Salt Lake City, UtahAges 18 years+ - NCT06715306Recruiting
IV vs. Oral Antibiotics for Common Infections
This trial compares starting antibiotics through a vein (IV) to taking them by mouth for common infections like pneumonia, urinary tract infections, or skin infections (cellulitis). The goal is to see if oral antibiotics work just as well without the need for an IV line.
Aabenraa, Southern DenmarkAges 18 years+ - NCT06705803Recruiting
Prostate cancer ablation registry study
This study collects information from men with prostate cancer who are having or have had a procedure to destroy prostate tumors (ablation). It aims to track outcomes over time to improve future treatments.
Hyde Park, IllinoisAges 22 years+ - NCT06709573RecruitingPhase 4
Early vs. late vasopressin for septic shock
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
Cleveland, OhioAges 18 years+ - NCT06715735Recruiting
A health coaching program for metabolic syndrome with kidney disease
This trial tests if a personalized health coaching program can help people with metabolic syndrome and chronic kidney disease make lasting lifestyle changes. If you have both conditions and are not yet on dialysis, this program may help you manage your health.
Chengdu, SichuanAges 18 years+ - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+ - NCT06503588Recruiting
No ureteral stent change for urinary infections
This trial tests whether leaving a ureteral stent in place during a urinary tract infection is safe. It may help avoid unnecessary procedures for patients with an indwelling ureteral catheter who develop a urinary infection.
Nancy, LorraineAges Any age - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT06702449RecruitingPhase 1/Phase 2
UTI vaccine safety and immune response study for adults 18-64
This trial tests a new vaccine to prevent urinary tract infections (UTIs). It first checks safety and immune response in healthy adults, then in women with recent E. coli UTIs. The goal is to see if the vaccine can reduce future infections.
Lenexa, KansasAges 18–64 - NCT06693661Recruiting
Learning to improve kidney care for Black patients
This study tests a program to help Black patients with advanced kidney disease learn about their condition and treatment options. It aims to see if this learning program can improve health outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT06701825RecruitingPhase 4
Genetic testing before tacrolimus in kidney transplant
This study tests whether doing a simple genetic test before starting the anti-rejection drug tacrolimus can lead to better dosing and outcomes in kidney transplant patients. It also looks at whether this approach is cost-effective.
Madrid, MadridAges Any age - NCT06703476RecruitingPhase 3
Surgery techniques study for bladder cancer
This trial compares two different surgical approaches during bladder removal surgery: using a stent or not, and using a drug called alvimopan or not. Alvimopan helps the bowels work normally after surgery.
Basking Ridge, New JerseyAges 21 years+ - NCT06704191RecruitingPhase 1/Phase 2
Bladder cancer treatment at home
This trial tests whether patients with early-stage bladder cancer can safely receive their usual bladder chemotherapy or immunotherapy at home instead of in the clinic. It aims to make treatment more convenient while keeping it effective.
Jacksonville, FloridaAges 18 years+ - NCT06694558Recruiting
Monocytes in type 1 diabetes and kidney disease study
This study looks at immune cells (monocytes) in people with type 1 diabetes, with or without early kidney problems. Researchers want to understand how these cells differ between groups. You may be able to join if you have type 1 diabetes and use an insulin pump or injections along with a continuous glucose monitor (CGM).
Cleveland, OhioAges 18–65 - NCT06700057Recruiting
Study of lutetium treatment for prostate cancer
This study looks at patients treated with a radioactive drug called 177Lu-PSMA-617 for a type of prostate cancer that has spread, stopped responding to hormone therapy, and has been treated with chemotherapy. It checks how the treatment affects the body and the tumor using images.
BordeauxAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,386 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,845 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.