Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT06493526RecruitingPhase 4
Mycophenolate therapy for kidney transplant patients with no DQ mismatch
This trial tests a mycophenolate-based therapy for kidney transplant recipients who have no HLA-DQ mismatch. If you had your first kidney transplant 3-12 months ago without DQ mismatch and are on standard immunosuppressants, you may qualify.
Edegem, AntwerpAges 18 years+ - NCT06493292Recruiting
Treating a blocked dialysis fistula with balloon therapy
This trial tests a balloon treatment for blocked blood vessels in the arm used for dialysis. It aims to improve blood flow so dialysis can work better.
Zhengzhou, HenanAges 18–75 - NCT06549465RecruitingPhase 2
Ac-225 rosopatamab for PSMA-positive castration-resistant prostate cancer
This trial tests a radioactive drug (Ac-225 rosopatamab tetraxetan) that targets a protein called PSMA on prostate cancer cells. It is for patients whose cancer has stopped responding to hormone therapy and has spread to other parts of the body.
San Diego, CaliforniaAges 18 years+ - NCT07183696Recruiting
Breathing muscle training for kidney dialysis patients
This study tests if breathing exercises can improve quality of life for people on kidney dialysis. You would do special breathing training using a device called a Breath Booster to help strengthen your breathing muscles.
GizaAges 50–60 - NCT06190197RecruitingEarly Phase 1
Testing antibiotics before bladder removal surgery
This trial tests whether giving preventive antibiotics before bladder removal surgery reduces infections. If you have muscle-invasive bladder cancer and are having your bladder removed, you may be able to join.
Minneapolis, MinnesotaAges 18 years+ - NCT07554300Recruiting
Pelvic floor exercises for post-urination dribbling in men
This study tests whether targeted pelvic floor muscle exercises (the muscles you use to stop urination) can reduce unwanted urine leakage that happens after you finish urinating. If the exercises work, it could offer a non-surgical treatment option.
Al Mansurah, EldakahliyaAges 18–40 - NCT06314230Recruiting
Genomics of chronic kidney transplant failure study
This study looks at how genes affect long-term kidney transplant health. It aims to understand why some transplanted kidneys fail over time, and may help personalize care for transplant recipients.
Westmead, New South WalesAges 18–75 - NCT06696430Recruiting
Nudging to use TENS for pain after surgery
This trial tests whether a simple reminder (nudging) can encourage staff and patients to use a device called TENS, which uses mild electrical pulses to help reduce pain after urological surgery.
Gothenburg, VGRAges 18 years+ - NCT06085183RecruitingPhase 4
Study of a dye to check ureters during surgery in people with kidney problems
This trial tests a blue dye (Bludigo) to help doctors see if the ureters are open during surgery. It is for people with normal or reduced kidney function who need a procedure where the ureters are checked.
Albany, New YorkAges 18–85 - NCT06352736Recruiting
Study on urinary symptoms in Chinese men over 40
This study looks at how common lower urinary tract symptoms are in Chinese men aged 40 and older. By participating, you can help researchers understand the impact of these symptoms and find better ways to help people like you.
BeijingAges 40 years+ - NCT07600541Recruiting
Kidney Transplant Recipients' Views on AI in Medicine
This study asks kidney transplant recipients about their thoughts and feelings regarding artificial intelligence (AI) used in medicine. Your feedback helps researchers understand how patients view AI tools that could help with their transplant care.
Paris, Île-de-France RegionAges 18 years+ - NCT06709196RecruitingPhase 4
Targeted antibiotics to prevent infections after bladder removal
This trial tests if using a personalized antibiotic approach before surgery can reduce infections compared to the usual one-size-fits-all antibiotics. It focuses on people having their bladder removed (cystectomy) with a specific type of urinary diversion.
AalborgAges 18 years+ - NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Alabaster, AlabamaAges 10–65 - NCT07111260Recruiting
Using a pHA130 filter for 4 hours during dialysis
This study tests a special filter called pHA130 that is used during your regular hemodialysis sessions for a full 4 hours. The purpose is to see if it helps improve your dialysis treatment outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT07040865RecruitingPhase 4
Comparing two MRI dyes for kidney and adrenal findings
This trial compares two different dyes (gadopiclenol and gadobutrol) used during MRI scans for people with unexpected kidney or adrenal findings. The goal is to see which dye works better for getting clear images of these areas.
BernAges 18 years+ - NCT06434350RecruitingPhase 1/Phase 2
Enfortumab vedotin and radiation for advanced bladder cancer
This trial tests a drug called enfortumab vedotin combined with radiation therapy for people with locally advanced bladder cancer that hasn't spread to distant organs. The goal is to see if this combination works better than radiation alone and helps control the cancer.
Houston, TexasAges 18 years+ - NCT06511349RecruitingEarly Phase 1
YOLT-203 for type 1 primary hyperoxaluria (PH1)
This trial tests an experimental drug called YOLT-203 for people with type 1 primary hyperoxaluria (PH1), a rare condition that causes high oxalate levels and can damage the kidneys. It aims to see if YOLT-203 can safely help manage the disease.
Shanghai, Shanghai MunicipalityAges 2 years+ - NCT07572227Enrolling by invitation
Fetal Surgery for Blocked Bladder in Male Babies
This trial tests a minimally invasive surgery (fetal cystoscopy) performed during pregnancy to help male babies with severe bladder obstruction. The goal is to prevent kidney damage and improve outcomes after birth.
Rochester, MinnesotaAges 18 years+ - NCT07098351Recruiting
A trial for a new itchy skin medicine for people on peritoneal dialysis
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
Guangzhou, GuangdongAges 18–85 - NCT05833867RecruitingPhase 1
Bladder cancer trial combining radiation and Sacituzumab
This Phase 1 study tests whether a new bladder-cancer treatment plan—radiation given at the same time as sacituzumab govitecan—can help people with muscle-invasive bladder cancer without starting with traditional chemo/radiation. Because it’s early-stage, the main goal is safety and learning the best way to use this combination to preserve the bladder.
Cleveland, OhioAges 18 years+ - NCT07011238Recruiting
Memory B cells and anti-HLA antibodies in kidney transplant patients
This study looks at how memory B cells (a type of immune cell) relate to antibodies against HLA in people waiting for a kidney transplant. It aims to better understand immune responses, which could help improve transplant matching and outcomes.
RouenAges 18 years+ - NCT06384079Recruiting
How long to rest the ureter before repair surgery
This trial compares different lengths of time for resting the ureter (with a drainage tube) before surgery to fix a narrowed ureter. It helps doctors find the best timing for better surgical outcomes.
Chicago, IllinoisAges 18 years+ - NCT05837806RecruitingPhase 2
Tislelizumab and disitamab as pre-surgery treatment for HER2 UTUC
This trial tests whether giving tislelizumab plus disitamab vedotin before surgery (neoadjuvant therapy) can improve outcomes for people with HER2-positive, high-risk upper tract urothelial cancer. It also looks at the treatment’s safety and helps doctors learn if certain tumor features predict response.
TianjinAges 18 years+ - NCT06987877Recruiting
Saline flushes to keep kidney tubes working
This study tests if flushing a kidney drainage tube with saline helps prevent blockages. It may help people who have a tube in their kidney and need it for at least 12 weeks.
Boston, MassachusettsAges 18–80
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.