Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT06855524RecruitingPhase 2
Seaweed supplement for less fatigue during chemotherapy
This study tests whether fucoidan, a supplement from brown seaweed, can help reduce fatigue caused by chemotherapy. Doctors at Mayo Clinic want to see if taking fucoidan during chemo helps you feel less tired.
Scottsdale, ArizonaAges 18 years+ - NCT07807956RecruitingPhase 1
Intravenous study drug for advanced solid tumors
This trial tests an investigational drug given through an IV to see if it can help people with advanced solid tumors. It aims to learn about side effects, how the drug works in the body, and whether it can slow or shrink the cancer.
Grand Rapids, MichiganAges 18 years+ - NCT06968845RecruitingPhase 2
Study of LTI-03 for Idiopathic Pulmonary Fibrosis
This trial tests an inhaled drug called LTI-03 to see if it can help people with idiopathic pulmonary fibrosis (IPF). It may be an option for those with moderate lung function who are stable on their current treatment.
Birmingham, AlabamaAges 40 years+ - NCT06948097RecruitingPhase 1
Testing fostamatinib for lung transplant patients with donor-specific antibodies
This trial tests a new medicine called fostamatinib for people who have had a lung transplant and have developed donor-specific antibodies (DSA) on their lung. The goal is to see if this medicine is safe and can help prevent the body from rejecting the new lung.
Stanford, CaliforniaAges 18–99 - NCT04790253Recruiting
Check brain radiation timing or frequent MRI scans for SCLC
This study compares two ways to follow and treat small-cell lung cancer in the brain: preventive brain radiation versus close monitoring with MRI scans and treatment only if needed. It may help people avoid unnecessary brain treatment or choose the safer timing strategy.
GrazAges 18 years+ - NCT07587658RecruitingPhase 4
Dupilumab after a severe COPD flare-up
This study tests whether adding the drug dupilumab to usual hospital care for a severe COPD flare-up helps patients recover better than usual care alone. It is for adults with a specific type of inflammation in their blood, and may reduce the chance of future flare-ups.
Mullica Hill, New JerseyAges 40 years+ - NCT06634810Recruiting
Home-based coaching for COPD self-management
This study tests a home-based coaching program called SAMBA-COPD to help people with COPD manage their symptoms and stick with their medications. You'll work with a coach who will support you in building skills to feel better and have fewer flare-ups.
New York, New YorkAges 40 years+ - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT07222670RecruitingPhase 2
Nasal spray to prevent respiratory infections in healthy adults
This trial tests a nasal spray, INNA-051, that may help your nose and airways fight off viruses that cause respiratory infections like colds and flu. It is for healthy adults aged 18-45 who are around many people and may be exposed to germs.
Baltimore, MarylandAges 18–45 - NCT06114888Recruiting
New diagnostic tests for children hospitalized with pneumonia
This study tests new ways to diagnose pneumonia in children who are hospitalized. It aims to find the best methods to quickly identify the cause of pneumonia, so your child can get the right treatment sooner.
Hamilton, OntarioAges 6 months–18 years - NCT07093580RecruitingPhase 1
Study of a long-acting injectable in healthy adults
This study tests a new long-acting injectable medication (S-892216 LAI) in healthy adults. It helps researchers understand how the drug works in the body when given as a shot, which could lead to a treatment given less often in the future.
Cypress, CaliforniaAges 18–55 - NCT07615764Recruiting
Lung cancer education for American Indian and Alaska Native smokers
This study tests an educational program called the Lung Toolkit that aims to improve knowledge about lung cancer and screening among American Indian and Alaska Native smokers. It may help you understand lung cancer risks and screening options.
Seattle, WashingtonAges 50–80 - NCT06270199RecruitingPhase 2
Stem cells for lung disease in preterm infants
This trial tests if stem cells can help premature babies with severe lung disease (bronchopulmonary dysplasia). It is for very small, early-born babies who still need a breathing machine between 5 and 14 days after birth.
Pozuelo de Alarcón, MadridAges 1 month–6 months - NCT06455800Recruiting
Severe lung disease in childhood
This study looks at severe lung disease in children. It may help doctors better understand and treat these conditions.
OdenseAges 1 day–18 years - NCT06623422RecruitingPhase 3
Vaccine plus Keytruda for lung cancer after surgery
This trial tests combining a cancer vaccine (V940) with the immunotherapy drug pembrolizumab (Keytruda) for people with non-small cell lung cancer that was treated with chemo and Keytruda before surgery but wasn't completely removed. The goal is to see if adding the vaccine helps prevent the cancer from coming back.
Gilbert, ArizonaAges 18 years+ - NCT06273072RecruitingPhase 2
Metformin for asthma in overweight adults
This trial tests whether the diabetes drug metformin can help people with asthma who are also overweight or obese. The goal is to see if it improves asthma control and reduces the need for rescue medications.
Baltimore, MarylandAges 18 years+ - NCT07610395RecruitingPhase 2
Testing an oral drug for cold virus in COPD patients
This trial tests an oral medication (VPV) to see if it can safely treat rhinovirus (a common cold virus) in people with COPD. The goal is to help you recover faster and prevent serious COPD flare-ups.
Mobile, AlabamaAges 40–85 - NCT07038343RecruitingPhase 1/Phase 2
Testing a new drug for advanced solid tumors
This trial tests a new drug called AVZO-1418, either alone or with other treatments, for people with advanced solid tumors that have spread or cannot be removed. The goal is to see if the drug is safe and effective against certain types of cancer.
Gilbert, ArizonaAges 18–75 - NCT07733141Recruiting
Mindfulness program for chronic graft-versus-host disease symptoms
This study tests whether a mindfulness program can help reduce symptoms and improve quality of life for people living with chronic graft-versus-host disease (cGVHD). You would attend group sessions (in person or virtual) to learn mindfulness techniques.
Duarte, CaliforniaAges 18 years+ - NCT03197363Enrolling by invitation
Long-term study of adults living in Białystok
This study follows adults living in Białystok over time to learn about health and life patterns. If you’re invited to take part and agree, it may help researchers better understand community health.
BialystokAges 20–80 - NCT07667400RecruitingPhase 1/Phase 2
Docetaxel plus SX-682 for advanced head and neck or prostate cancer
This trial studies a combination of the chemotherapy drug docetaxel and an investigational drug called SX-682 for people with certain advanced head and neck cancers or prostate cancer. The goal is to see if the combination is safe and effective.
Bethesda, MarylandAges 18–120 - NCT06179069RecruitingPhase 1
Study of ZL-1310 for small cell lung cancer
This trial tests a new drug called ZL-1310, alone or with other treatments, for people with small cell lung cancer that has spread (extensive-stage). It aims to see if ZL-1310 can help shrink tumors or slow the disease.
Duarte, CaliforniaAges 18 years+ - NCT07526077Enrolling by invitation
Better Breathing Preparation During Spine Surgery
This trial tests a new way to prepare the airway (breathing tube insertion) during major spine surgery under general anesthesia. The goal is to keep your heart and brain better oxygenated during the procedure.
Riyadh, Saudi ArabiaAges 18–70 - NCT07388524RecruitingPhase 3
Testing atezolizumab after surgery for early stage lung cancer
This trial tests if the immunotherapy drug atezolizumab can prevent early stage non-small cell lung cancer from coming back after surgery. It is for people whose tumors have high levels of a protein called PD-L1 (50% or more) and do not have certain gene changes (EGFR or ALK).
Beverly Hills, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.