Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT05228691Recruiting
Study Long COVID symptoms in the Canary Islands
This study looks at how common long-term COVID symptoms are in people across the Canary Islands. It may help researchers better understand who is affected and what symptoms last, which can support future care.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT05229614RecruitingPhase 2
Immunotherapy plus carbon ion radiation for stable solid tumors
This trial studies whether adding carbon ion radiation to ongoing immunotherapy can help people whose cancer is currently stable. It targets solid cancers where scans show the disease is not growing quickly, aiming to improve control without causing unsafe side effects.
DarmstadtAges 18 years+ - NCT05233605Recruiting
Study sedative effects on ongoing brain inflammation after severe COVID
This study looks at whether a specific ICU sedative (dexmedetomidine) affects long-term inflammation in the brain after severe COVID with ARDS and deep sedation. It uses PET and MRI scans and special tracers to understand persistent inflammation and why it may last.
ParisAges 18–74 - NCT05234307RecruitingPhase 1
Nivolumab plus PBF-1129 for advanced lung cancer
This Phase 1 trial tests a new combination of PBF-1129 with nivolumab (an immune therapy) for lung cancer that has come back or spread. It aims to find a safe dose and see whether the combination can shrink tumors and improve outcomes.
Columbus, OhioAges 18 years+ - NCT05235685Recruiting
Testing muscle fatigue during exercise in COPD and heart failure
This study looks at how tired your muscles get during a controlled cycling exercise test in people who have COPD, and—if applicable—heart failure at the same time. It may help researchers understand exercise limits and how to better support you with these conditions.
Échirolles, Auvergne-Rhône-AlpesAges 18 years+ - NCT05236062Recruiting
Exercise during steroid treatment for GVHD
This study looks at whether doing moderate-to-vigorous exercise can reduce complications from corticosteroids in people with newly diagnosed GVHD. It may help your body tolerate steroids better, while checking exercise safety during treatment.
Boston, MassachusettsAges 18 years+ - NCT05236114Recruiting
Study of blood and tumor tests for lung cancer treatment
This study looks at how tumor and blood biomarker results can guide treatment for people with non-small cell lung cancer (NSCLC). Depending on the cancer stage, it may follow standard-of-care treatment plans around surgery or first-line immunotherapy.
Birmingham, AlabamaAges 18 years+ - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05241028RecruitingPhase 2
Adjuvant ensartinib for ALK-positive lung cancer after surgery
This trial studies whether taking ensartinib (a targeted pill) after lung cancer surgery can lower the chance the cancer comes back. It is for people with ALK-positive non-small cell lung cancer (NSCLC) whose cancer has been fully removed and who have recovered from treatment.
Shijiazhuang, HebeiAges 18–75 - NCT05242159Recruiting
COVID-19 antibody study in hospitalized patients
This research study examines a specific type of antibody (anti-annexin A2) that may develop during COVID-19 infection. By studying hospitalized COVID-19 patients, researchers hope to understand whether these antibodies are common and what role they might play in COVID-19 illness.
AmiensAges 18 years+ - NCT05242393Recruiting
How daily body rhythms relate to recovery after stroke
This observational study looks at how your body’s daily rhythms may affect brain recovery after an ischemic stroke. It may help researchers understand what timing-related factors influence “neuroplasticity,” meaning the brain’s ability to adjust and heal.
Saint PetersburgAges 18–80 - NCT05244239RecruitingPhase 1
Radiation plus lurbinectedin for advanced small cell lung cancer
This trial studies whether adding palliative (comfort-focused) radiation to the medicine lurbinectedin can better control extensive-stage small cell lung cancer. It may help reduce problems from tumors in places like bones and organs.
Atlanta, GeorgiaAges 18 years+ - NCT05245500RecruitingPhase 1
Study drug for solid tumors with MTAP gene deletion
This Phase 1 trial studies MRTX1719, a new medicine, in solid tumors that have a missing MTAP gene (MTAP deletion). It aims to find the safest dose and check how the drug affects the tumor.
Phoenix, ArizonaAges 18 years+ - NCT05246098Recruiting
Rehabilitation program study for young and adult ICU COVID/respiratory survivors
This study looks at whether a rehabilitation approach improves recovery outcomes for people who survived COVID-19 or a serious breathing infection and needed ICU/PICU care. It may help those still dealing with physical or functional problems after their critical illness.
Calgary, AlbertaAges Any age - NCT05248230RecruitingPhase 2
Study drug for adults with cystic fibrosis lung disease
This Phase 2 trial tests 4D-710 to improve lung health in adults with cystic fibrosis who either cannot take CFTR modulator medicines or are not doing well enough on them. You may be eligible if you have moderate lung function and stable oxygen levels, and you meet other safety and health requirements.
Birmingham, AlabamaAges 18 years+ - NCT05248412Recruiting
Study how COVID-19 long-term effects impact chronic diseases
This research looks at how the COVID-19 pandemic has affected the health and healthcare of adults with long-term conditions like diabetes, high blood pressure, heart disease, cancer, kidney disease, or chronic lung disease. It compares people who may have been affected by the pandemic and looks at their health and access to care over time.
Hong Kong, Hong KongAges 18 years+ - NCT05248763Recruiting
Cancer Moonshot program for specific cancer types
This study is for people with certain cancers: lung, breast, gastric (stomach), pancreatic, or ovarian. It aims to test a Moonshot-style approach to improve cancer care for these groups.
TaipeiAges 20 years+ - NCT05254184RecruitingPhase 1
Vaccine and immunotherapy for KRAS-mutated lung cancer
This Phase 1 study tests a KRAS-targeted vaccine combined with chemo and immunotherapy (nivolumab and ipilimumab) for people with advanced non-small cell lung cancer. It aims to help the immune system recognize and fight tumors with specific KRAS mutations, and to see if the treatment is safe and effective enough to study further.
Baltimore, MarylandAges 18–100 - NCT05254431Recruiting
Exercise timing program for breathing trouble and sleep apnea
This trial tests whether doing exercise at set intervals can improve daily function in Veterans who have both COPD (lung disease) and OSA (sleep apnea). It may help you move and function better while managing symptoms from both conditions.
Salem, VirginiaAges Any age - NCT05254782Recruiting
Blood test after lung tumor surgery to find hidden disease
This study uses a special blood test to look for tiny traces of lung cancer after surgery. It aims to find “minimal residual disease,” meaning cancer cells that may still be hiding after your tumor is removed.
Toronto, OntarioAges 18 years+ - NCT05255302RecruitingPhase 2/Phase 3
Shorter immune maintenance for stage IV lung cancer after initial treatment
This trial tests whether giving immune therapy maintenance for a shorter time helps people with stage IV non-small cell lung cancer (NSCLC) who are doing well after initial chemo-immunotherapy. It aims to keep the cancer controlled while possibly reducing treatment exposure and side effects.
Aix-en-ProvenceAges 18–74 - NCT05257551Recruiting
Small cell lung cancer data study using tumor and blood samples
This observational study collects information and lab samples from people with extensive-stage small cell lung cancer. It may help researchers understand how patients respond and improve future care, but it usually does not add new treatment for you.
Los Alamitos, CaliforniaAges 18 years+ - NCT05257967Recruiting
Testing spinal fluid in EGFR-mutant lung cancer with brain covering spread
This trial looks at spinal fluid (also called CSF) in adults with EGFR-mutant lung cancer that has spread to the lining around the brain/spinal cord. The goal is to better understand the disease and what the spinal fluid tests may show to guide care.
Vancouver, British ColumbiaAges 18 years+ - NCT05258448Recruiting
Chemo-radiotherapy for advanced, non-surgical lung cancer
This trial studies treatment that combines chemotherapy and radiation for people with advanced lung cancer that cannot be removed with surgery. It may help improve cure chances for patients who can complete the study tests, including heart scans.
Odense CAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.