Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT05259904RecruitingPhase 2
L-citrulline supplement for deployment-related asthma symptoms
This trial studies whether an L-citrulline supplement can improve asthma control in people who developed persistent asthma symptoms after military deployment. If you qualify, you may be asked to track symptoms and breathing test results to see if the supplement helps.
Denver, ColoradoAges 18–70 - NCT05261607Recruiting
Study outcomes for people in the intensive care unit
This study looks at how mortality (whether patients survive) changes over time for people treated in an intensive care unit. It may help hospitals understand what happens to ICU patients and improve care planning.
Getafe, MadridAges Any age - NCT05261139RecruitingPhase 3
Trial for PF-07321332 for children at risk from COVID-19
This trial studies whether PF-07321332 (with ritonavir) helps children under 18 who have COVID-19 at home but are at high risk of severe illness. It looks at whether starting treatment early can reduce progression to worse disease.
Phoenix, ArizonaAges birth–17 years - NCT05262439Recruiting
Follow-up study of CPAP mask systems for sleep apnea
This study checks how ResMed CPAP mask systems work in real-life use for people with obstructive sleep apnea (OSA). It may help improve comfort, fit, and performance based on what patients experience over time.
Sydney, New South WalesAges 18–100 - NCT05265299RecruitingPhase 3
Testing the right aspirin dose for COPD symptoms
This Phase 3 trial studies which aspirin dose works best in people with COPD, with the goal of improving disease control. You may be asked to take aspirin and be monitored for safety, especially bleeding risk and heart/brain history.
Baltimore, MarylandAges 40–80 - NCT05265429Recruiting
Study of young people’s lung cancer biology
This study looks at biological samples from people diagnosed with lung cancer at age 45 or younger. It may help researchers understand how young lung cancers differ, which could guide future treatments.
Boston, MassachusettsAges 15 years+ - NCT05266222Recruiting
Collecting respiratory virus samples for a research library
This study collects samples from people who have or might have a cold/respiratory virus, then stores them for future research. It may help researchers better understand respiratory germs and develop better treatments.
Bethesda, MarylandAges 3 years+ - NCT05267041Recruiting
Lung cancer database study at Lyon hospitals
This study collects information about people who have been treated for lung or chest cancers at Lyon University Hospital. Your data may help researchers better understand these cancers and improve future care.
Pierre-BéniteAges 18 years+ - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05268523Recruiting
Online self-management program for long COVID symptoms
This trial tests an online self-management program to help people cope with long COVID symptoms in everyday life. It may help if you’re struggling with ongoing symptoms like mood changes, memory/thinking issues, or physical problems after COVID.
Toronto, OntarioAges 18 years+ - NCT05269485RecruitingPhase 1/Phase 2
Hypofractionated radiation for stage III lung cancer
This trial studies a radiation treatment schedule called “hypofractionated radiotherapy” for people with locally advanced (stage III) non-small cell lung cancer who cannot have surgery. It aims to see whether this radiation approach works well and is tolerable for your cancer stage.
Hefei, AnhuiAges 18–70 - NCT05271292RecruitingPhase 1/Phase 2
Chiauranib for advanced cancers that returned or won’t respond
This Phase 1/2 study tests chiauranib in people with advanced solid cancers (including small cell lung cancer) that have come back or no longer respond to standard treatments. It aims to find a safe dose and see whether the treatment can help shrink tumors.
Encinitas, CaliforniaAges 18 years+ - NCT05270616Recruiting
Robotic or video-assisted lung surgery compared
This trial compares robotic surgery and video-assisted surgery for removing part of the lung (lobectomy or segmentectomy). It may help determine which approach is safer or works better for patients who can safely tolerate minimally invasive surgery.
Jinan, ShandongAges 18–85 - NCT05270525RecruitingPhase 2
Ensifentrine nebulizer trial to reduce COPD airway inflammation markers
This trial tests ensifentrine, given through a nebulizer, to see if it changes inflammation-related substances found in mucus/phlegm in people with COPD. It may help doctors understand whether this treatment improves COPD biology and could lead to better symptom control.
Birmingham, AlabamaAges 40–80 - NCT05271669Recruiting
Study of COVID-19 immunity over time
This study looks at how people’s immune protection after COVID-19 may change over time. It aims to better understand immunity, which could help doctors plan future care and prevention.
Hong Kong, HONG KONGAges Any age - NCT05271916RecruitingPhase 1/Phase 2
New targeted drugs for advanced lung cancer with EGFR L858R
This study tests whether taking dacomitinib plus anlotinib as a first treatment can shrink or control advanced lung cancer that has the EGFR L858R mutation. It may help people who have not had any standard drug treatment yet, especially if their brain metastases are stable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05273190Recruiting
Using gentle larynx stimulation to treat chronic unexplained cough
This study tests whether stimulating the larynx (voice box area) can reduce cough that has lasted more than 8 weeks. It may help people whose cough is not clearly explained by infections, lung diseases, or other common causes.
Minneapolis, MinnesotaAges 18–88 - NCT05278052RecruitingPhase 3
Maintenance therapy alone versus radiation plus maintenance for lung cancer
This trial compares standard maintenance treatment versus adding focused radiation to remaining limited (oligometastatic) spots in the body after initial chemotherapy. It aims to see whether treating those limited spots with radiation can improve outcomes without unacceptable side effects.
Mumbai, MaharashtraAges 18–99 - NCT05277844RecruitingPhase 2
Radiation plus targeted pill vs pill alone for EGFR/ALK-NSCLC
This study tests whether adding focused radiation to a targeted cancer pill works better than the pill by itself. It is for people with advanced non-small cell lung cancer (NSCLC) whose tumor has an EGFR or ALK/ROS driver mutation and who have not gotten worse after starting the targeted pill.
Mumbai, MaharashtraAges 18–99 - NCT05279040Recruiting
Trikafta plus exercise program for adults with cystic fibrosis
This study tests how starting Trikafta affects exercise ability and breathing in adults with cystic fibrosis. You may be asked to do supervised breathing and exercise tests to see if Trikafta helps your lung function and stamina.
Vancouver, British ColumbiaAges 19 years+ - NCT05281406RecruitingPhase 2
Extra chemotherapy if tumor DNA stays positive after osimertinib
This Phase 2 trial tests whether adding chemotherapy can help people with EGFR-mutated lung cancer when their cancer-related blood test (liquid biopsy for EGFR DNA) is still positive after 3–4 weeks of starting osimertinib. It may help slow the cancer for longer by treating any remaining disease activity.
BerlinAges 18 years+ - NCT05281237Recruiting
Microwave ablation for small early lung cancer nodules
This trial studies a flexible “microwave heating” probe placed through the airways to treat small lung cancer nodules. It may help some patients avoid more invasive treatment by destroying the tumor during a bronchoscopy procedure.
Boston, MassachusettsAges 22 years+ - NCT05281952Recruiting
Tested ways to treat severe nosebleeds after failed packing
This study looks at different management strategies for severe nosebleeds when the initial packing method has not worked for over 48 hours. It also measures the cost/benefit of these approaches to help improve care.
ToulouseAges 18 years+ - NCT05283330RecruitingPhase 1
Tested 212Pb imaging drug for certain advanced GRPR tumors
This early-phase study tests how safe and tolerable an experimental radiation drug is for adults with certain advanced or metastatic cancers that show a target called GRPR. Doctors will also use special scans to confirm the tumor has the target so the treatment can be delivered to the right place.
Chicago, IllinoisAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.