Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05513508Recruiting
Tested a protective breathing mask in COPD and respiratory failure
This study tests how well a specific breathing mask setup works in people who need noninvasive ventilation (breathing support without a breathing tube), especially during COPD flare-ups or certain kinds of breathing failure. It may help reduce complications related to the mask while supporting breathing for at least a day.
NovaraAges 18 years+ - NCT05517655RecruitingPhase 4
Cystic fibrosis blood/sweat check using MRI in children
This study looks at new “imaging biomarkers” (MRI measurements) in children with cystic fibrosis (CF). It mainly aims to see how MRI findings might relate to starting the recommended CF triple-combination therapy.
Kansas City, KansasAges 6–8 - NCT05520762Recruiting
Trial for patients after in-hospital cardiac arrest needing breathing support
This trial studies a hospital treatment for people who have a cardiac arrest while in the hospital and still need help breathing. It may help improve care right after this emergency by testing an airway resuscitation approach.
New York, New YorkAges 18 years+ - NCT05521789RecruitingPhase 4
Erector spinae block for thoracic surgery pain relief
This trial tests a specific pain-block injection (called an erector spinae block) to help with pain during thoracic surgery that removes part of the lung. You might benefit from better pain control and possibly fewer pain medicines, depending on what the study finds.
Washington D.C., District of ColumbiaAges 18–90 - NCT05522660RecruitingPhase 3
Immunotherapy or targeted therapy with focused brain radiation
This Phase 3 study tests whether immunotherapy or targeted medicine, with or without a one-time focused brain radiation procedure, can control brain metastases from melanoma or non-small cell lung cancer. It mainly enrolls people who have no (or minimal) brain symptoms and are newly diagnosed in the brain (except for certain recent brain surgery).
NaplesAges 18 years+ - NCT05525169Recruiting
Study how indoor and outdoor pollution affects asthma
This study looks at whether exposure to air pollution inside and outside your home affects asthma symptoms and flare-ups. You may be asked to use sensors at home to measure pollution levels and link them to your asthma over time.
NantesAges 18–99 - NCT05525338RecruitingPhase 4
Test standard vs adjusted alectinib dose using blood levels
This trial compares the usual dose of alectinib with a modified dose chosen by checking alectinib blood levels. It aims to see whether adjusting the dose based on blood testing can work as well (and possibly be better tolerated) for people with ALK-positive non-small cell lung cancer.
Villejuif, Val-de-MarneAges 18 years+ - NCT05525312Recruiting
Two breathing strategies during lung surgery for lung cancer
This trial compares two ways of managing breathing while you have surgery to remove lung cancer. It may help doctors figure out which strategy is safer and works better during the operation.
MontpellierAges 18 years+ - NCT05526105Recruiting
Ultrasound for stomach fluid in ICU patients
This trial tests using an ultrasound scan to estimate stomach fluid and volume in ICU patients. It may help clinicians better assess aspiration risk and prepare for safe anesthesia or procedures.
Lebanon, New HampshireAges 18–100 - NCT05530408Recruiting
Pulmonary scan imaging registry and blood sample collection
This trial builds a research database from people who take lung scans like pulmonary MRI or CT at the University of Kansas Medical Center. It may help researchers better understand lung disease and improve future diagnosis or treatment.
Kansas City, KansasAges 18 years+ - NCT05531773Recruiting
Study for ongoing symptoms after COVID-19
This trial studies people with mild to moderate COVID-19 symptoms to better understand and help “post-COVID” condition (ongoing effects after infection). You may be eligible if you’re an adult with a recent confirmed COVID-19 test and you agreed to take part.
DüsseldorfAges 18 years+ - NCT05532566Recruiting
Tested oak tree allergy extracts for people with inhalant allergy
This trial studies how well standardized oak (Quercus ilex and Quercus robur) allergen extracts match your specific allergy. It may help refine allergy testing and treatment planning for people with oak-triggered rhinitis, eye symptoms, and/or asthma.
MadridAges 18–64 - NCT05532696RecruitingPhase 1/Phase 2
Testing ABT-101 for advanced solid tumors and HER2-mutant lung cancer
This study tests ABT-101, a new experimental treatment, in people with advanced solid tumors. A second part specifically looks at people with non-small cell lung cancer (NSCLC) that has HER2 mutations, to see how well the treatment works and how safe it is.
TaichungAges 18 years+ - NCT05534009Recruiting
Study of healthcare workers’ COVID infection and vaccine history
This study gathers information about healthcare workers (adults) and tracks your past COVID-19 infection and vaccination history. It may help researchers understand how COVID affects healthcare workers and how vaccines relate to infection outcomes.
DüsseldorfAges 18 years+ - NCT05535543Recruiting
Prone breathing position test for severe lung failure
This trial studies whether turning patients onto their stomach (a positioning technique called prone positioning) changes a breathing-monitoring measure in people with severe acute respiratory distress syndrome (ARDS). If you qualify, the goal is to see if this positioning can improve how well your lungs exchange oxygen while you are on a breathing machine.
IstanbulAges 18 years+ - NCT05536076Recruiting
Breathing treatment to help recovery after spinal cord injury
This study tests whether a breathing-support treatment (for abnormal breathing during sleep) can improve breathing recovery in people living with a spinal cord injury. It aims to see if treating higher carbon dioxide levels and sleep-breathing problems leads to better breathing and recovery.
Detroit, MichiganAges 18–89 - NCT05536219Recruiting
Study how autoantibodies affect virus levels in severe lung infections
This study measures blood immune “autoantibodies” that may affect how much virus is in the body during severe respiratory infections. It may help doctors understand which patients are more likely to have higher virus levels and could guide future treatment choices.
Bron, RhoneAges Any age - NCT05537922Recruiting
Study uses data to tailor lung cancer care with immunotherapy
This study collects and analyzes medical information (and sometimes tissue samples) to help personalize treatment plans for advanced non-small-cell lung cancer using immunotherapy. It may help researchers find which people benefit most and how treatment can be better matched to each patient.
Chicago, IllinoisAges 18 years+ - NCT05538806Recruiting
Testing NovoTTF device use in routine treatment for pleural mesothelioma
This trial studies using the NovoTTF-200T device as part of regular care for people with pleural mesothelioma when surgery that could cure the cancer isn’t an option. It may help doctors understand how well this device fits into real-world treatment and outcomes.
Gauting, BavariaAges 18 years+ - NCT05539014Recruiting
Study of newly diagnosed tuberculosis patients at Avicenne Hospital
This study follows people who are newly treated for tuberculosis, including lung and non-lung (extra-lung) cases. It may help doctors better understand tuberculosis and how patients respond after treatment starts.
BobignyAges 18–80 - NCT05539482Recruiting
Community education to help detect COVID-19 early and prevent illness
This study tests community-based health education in Hong Kong to help people recognize COVID-19 early, get vaccinated, and use everyday self-protective steps. It may help participants learn practical ways to lower their risk and respond sooner if symptoms appear.
Hung HomAges 12 years+ - NCT05539560Recruiting
Olfactory training for loss of smell after COVID-19
This trial studies whether daily smell training can improve smell loss caused by COVID-19. It may help people regain smell and possibly reduce related symptoms like distorted smells.
CopenhagenAges 18 years+ - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.