Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05329714Recruiting
Deep testing registry for people with pulmonary hypertension
This trial is a global registry that collects detailed health information (“deep phenotyping”) from people diagnosed with pulmonary hypertension. It helps researchers better understand the condition and how people differ, which can guide better future treatments.
Giessen, HesseAges Any age - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05582044Recruiting
Exercise using leg suction for heart failure with preserved function
This study tests whether a specific lower-body exercise method using negative pressure (leg suction) can improve symptoms and heart-related function in people with heart failure with preserved ejection fraction (HFpEF). You may also be offered screening if you are a healthy person, to compare results.
Kelowna, British ColumbiaAges 40 years+ - NCT05756894Recruiting
Stimulation therapy to improve breathing after spinal cord injury
This trial studies a neurostimulation approach to help breathing problems after a spinal cord injury. You may be able to join if you have a certain type and level of spinal cord injury and breathing weakness, and you can safely attend study visits with caregiver support.
Chicago, IllinoisAges 18–85 - NCT05962164Recruiting
Passive heat therapy for COPD in non-smokers
This study tests whether using passive heat (warming therapy, not exercise) can improve breathing and body comfort in people with COPD who are not currently flaring up. It may help by seeing if heat changes how well you tolerate breathing and physical activity during testing.
Kelowna, British ColumbiaAges 40 years+ - NCT06740019RecruitingPhase 1
JMKX000197 for malignant pleural effusion in advanced cancer
This trial tests an investigational drug called JMKX000197 given into the chest to control fluid buildup caused by cancer. It is for people with advanced solid tumors that have led to a moderate or large pleural effusion requiring drainage.
BeijingAges 18–75 - NCT07228702Enrolling by invitationPhase 1
Bacteriophage therapy for one patient with lung infection
This is a special program for one patient with a lung infection from Mycobacterium abscessus. The trial uses a treatment with bacteriophages, which are viruses that attack specific bacteria.
Vancouver, British ColumbiaAges Any age - NCT06122233Recruiting
Digital self-management for fibrotic lung disease
This trial tests whether a digital self-management program (using a smartphone or tablet) helps people with fibrotic interstitial lung disease better manage their symptoms and quality of life. If you have this lung condition and can use a mobile device, this study could offer you extra support at home.
Sydney, New South WalesAges 18 years+ - NCT06397365Recruiting
Hypnosis for better CPAP use
This trial tests if hypnosis sessions can help people with sleep-disordered breathing use their CPAP machine more consistently, especially if they are currently using it less than 3 hours a night.
Lausanne, Canton of VaudAges 18 years+ - NCT06911606RecruitingPhase 2
Serplulimab with chemotherapy before surgery for limited-stage small cell lung cancer
This trial tests adding an immunotherapy drug called serplulimab to standard chemotherapy before surgery for limited-stage small cell lung cancer (LS-SCLC). The goal is to see if this combination helps shrink the tumor and improve outcomes for patients who have not received prior treatment.
Guangzhou, GuangdongAges 18–75 - NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT07223762Enrolling by invitation
Comparing two types of laryngoscope blades for intubation
This trial compares two types of laryngoscope blades (the tool used to guide a breathing tube) to see which works better for routine intubations. If you are an adult scheduled for a planned breathing tube placement, you may be able to join.
Birmingham, AlabamaAges 18 years+ - NCT07224490RecruitingPhase 1
Kisspeptin test for brain function after COVID-19
This study tests how the brain's reproductive hormone system works after a COVID-19 infection using a substance called kisspeptin. It may help explain symptoms like changes in periods or hormone levels in people with long COVID.
Boston, MassachusettsAges 18–60 - NCT07224971RecruitingPhase 2
Timing of immunotherapy for advanced cancer
This trial tests whether the time of day you receive immunotherapy (in the morning vs. later) affects how well it works. It is for people with advanced lung cancer or other solid tumors who are just starting or continuing PD-1/PD-L1 inhibitor treatment.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07224243Recruiting
How oxygen during surgery affects recovery
This study looks at how different oxygen levels during surgery affect recovery. It includes adults having surgery with a breathing tube, but excludes people having open-heart surgery, certain lung procedures, or who have had bleomycin chemotherapy.
Ann Arbor, MichiganAges 18 years+ - NCT07227623Recruiting
Digital health program to help lung cancer survivors get active
This trial tests a digital health tool to help lung cancer patients improve their physical function and wellness during and after treatment. It is designed for people with early-stage lung cancer who are starting treatment with chemotherapy, immunotherapy, or radiation.
Boston, MassachusettsAges 18 years+ - NCT07225036Recruiting
Low-dose liver radiation to boost immunotherapy
This trial tests whether adding a low dose of radiation to the liver can make standard immunotherapy work better for people with non-small cell lung cancer or melanoma that has spread to the liver.
Cincinnati, OhioAges 18 years+ - NCT07224152RecruitingPhase 1/Phase 2
NBTXR3 plus radiation for inoperable lung cancer
This trial tests a new drug called NBTXR3, which makes cancer cells more sensitive to radiation. You'll get one injection of NBTXR3 into your lung tumor, followed by standard radiation. It is for people with early-stage non-small cell lung cancer who cannot have surgery.
Houston, TexasAges 18 years+ - NCT07227480Recruiting
Lung cancer screening help via text message
This study uses text messages to help people get their yearly lung cancer screening. If you're between 50–80, have a significant smoking history, and haven't completed your annual screening yet, you may be able to join from home.
Rochester, New YorkAges 50–80 - NCT07225257Recruiting
Recovering Physical Function After ICU Stay in Older Adults
This study looks at how to help older adults regain physical strength after a serious illness that required time in the ICU. It aims to find the best ways to help you recover daily activities like walking and moving around.
Lexington, KentuckyAges 18–99 - NCT07224061Recruiting
Asthma management program using technology and care coordination
This trial uses a smartphone app and care coordination to help children ages 4–12 with uncontrolled asthma. It aims to improve asthma control and reduce symptoms by connecting clinics and schools.
The Bronx, New YorkAges 4–12 - NCT07228052RecruitingPhase 4
Steroid shot to prevent return to the ER for asthma
This trial tests whether a single steroid shot given in the emergency department can help prevent your asthma symptoms from coming back and keep you from needing to return to the ER.
The Bronx, New YorkAges 18 years+ - NCT07223424RecruitingPhase 2
Patient preference study: shot vs infusion for immunotherapy
This study compares two ways to take immunotherapy drugs (nivolumab or pembrolizumab): as a shot under the skin (subcutaneous) versus an infusion into a vein (intravenous). It looks at which method patients prefer and is for people with certain advanced cancers where these drugs are already approved.
Pittsburgh, PennsylvaniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.