Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT04631770Recruiting
Mediastinal node removal versus sparing nodes for early lung nodule
This trial compares two surgical approaches for people with a single small, noncancer-looking lung nodule (a GGN) that is diagnosed as very early lung cancer. It aims to see whether removing mediastinal lymph nodes—or leaving them alone—can lead to better outcomes with less harm.
Tianjin, Tianjin MunicipalityAges Any age - NCT03169010Recruiting
Study registry for rare lung artery blood pressure problems
This study collects information from people with rare types of pulmonary hypertension (high blood pressure in the lungs) and from healthy volunteers. It helps researchers better understand these conditions, especially using a special lung-heart test to confirm the diagnosis.
Beijing, Beijing MunicipalityAges Any age - NCT05724004Recruiting
Alectinib then targeted radiation for ALK-positive lung cancer
This trial tests giving alectinib first, then adding targeted radiation to remaining spots of cancer in people with ALK-rearranged advanced non-small cell lung cancer. It aims to control the cancer after an initial response and help keep disease from progressing.
StockholmAges 20 years+ - NCT05241028RecruitingPhase 2
Adjuvant ensartinib for ALK-positive lung cancer after surgery
This trial studies whether taking ensartinib (a targeted pill) after lung cancer surgery can lower the chance the cancer comes back. It is for people with ALK-positive non-small cell lung cancer (NSCLC) whose cancer has been fully removed and who have recovered from treatment.
Shijiazhuang, HebeiAges 18–75 - NCT05777278RecruitingPhase 1/Phase 2
Savolitinib plus docetaxel for advanced lung cancer with high MET
This trial studies savolitinib (an oral MET-targeted medicine) combined with docetaxel (an IV chemotherapy) in people with advanced non-small cell lung cancer (NSCLC) whose tumor has high MET activity. It’s designed to see if this combination can shrink tumors or control the cancer after the first standard treatment.
Guangzhou, GuangdongAges 18 years+ - NCT02419274Recruiting
Asthma group study for adults in Germany
This study follows adults with asthma to better understand the disease and help improve care. It checks basic eligibility such as diagnosis, language, and recent health history.
GroßhansdorfAges 18–99 - NCT06080776RecruitingPhase 3
SH-1028 vs placebo for early-stage EGFR-mutated lung cancer
This trial tests a pill called SH-1028 (an EGFR-targeted drug) versus a placebo to see if it helps prevent lung cancer from coming back after surgery in people with EGFR-mutated NSCLC. You may be eligible if you had complete removal of stage II-IIIB NSCLC and your tumor has a specific EGFR mutation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05306743Recruiting
Quality program for high-risk COPD, tested with primary care teams
This study looks at how well a quality-improvement program (called CONQUEST) helps people with higher-risk chronic lung disease (COPD) when delivered through primary care teams. It compares the program given right away versus usual care for a while, then the program later.
Denver, ColoradoAges 18 years+ - NCT06090838Recruiting
Balloon angioplasty for blood clots in the lungs after pulmonary embolism
This trial tests whether balloon angioplasty can improve breathing and exercise ability in people who still have symptoms and blood flow problems 3 months or more after a pulmonary embolism. It is for those who have completed a pulmonary rehabilitation program.
Amsterdam, North HollandAges 18–80 - NCT05176132Recruiting
Obesity screening to find hidden weight-related health issues
This study screens adults of different body sizes to find “unrecognized” weight-related health problems. It may help doctors spot issues earlier and understand how common they are across weight groups.
EsbjergAges 18–60 - NCT05600569Recruiting
Thoracic surgery registry study in Spain
This is a registry (a secure log) that collects information about patients who undergo thoracic (chest) surgery. It helps researchers understand what surgeries are being done and may improve planning and care over time.
ZaragozaAges Any age - NCT05550961Recruiting
Real-world study of innovative treatments for lung cancer
This study collects real-world information about people with lung cancer who get newer kinds of cancer drugs. It aims to understand how these innovative therapies work in everyday care and help future research.
MilanAges 18 years+ - NCT04586413Recruiting
Help build and study a quality-of-life tool after COVID-19
This study will collect information from adults who had COVID-19 (confirmed by a test or diagnosis) to develop and improve a questionnaire about life after infection. Your answers may help researchers better track symptoms and quality of life over time.
OxfordAges 18 years+ - NCT06092086RecruitingPhase 2
Lorlatinib for first-line treatment of ALK-positive lung cancer
This trial tests a targeted pill, lorlatinib, for people with advanced ALK-positive non-small cell lung cancer (NSCLC) who have not received previous treatment for advanced disease. It aims to see how well the drug works in this setting.
Guangzhou, GuangdongAges 18 years+ - NCT05997719Recruiting
Study of EGFR-mutated lung cancer evolution and markers
This study looks at how EGFR-mutated lung cancer changes over time and tries to find markers that can predict how well you might respond to treatment. You will provide a tumor sample for genetic analysis.
GuanzhouAges 18 years+ - NCT03263130Recruiting
Study breathing limits in overlap asthma-COPD
This trial looks at what causes breathing to become harder when you blow air out in people with asthma-COPD overlap, and in some people with emphysema or bronchiectasis. It may help researchers better understand your condition’s breathing problem and how to target it.
Lakewood, CaliforniaAges 30 years+ - NCT06102928Recruiting
Anlotinib plus Aumolertinib for first-line treatment of advanced EGFR-mutant lung cancer
This trial tests a combination of two targeted drugs (anlotinib and aumolertinib) as the first treatment for advanced lung cancer with a specific EGFR mutation (L858R). The goal is to see if the combination works better than standard care.
Kunming, YunnanAges 18 years+ - NCT01225913RecruitingPhase 4
Testing airflow limits in asthma flare-ups
This Phase 4 study looks at what causes breathing airways to narrow during asthma worsening, in people with stable, treated asthma. It may help improve how clinicians understand and manage asthma flare-ups.
Lakewood, CaliforniaAges 10–80 - NCT00576069Recruiting
Study airflow limits in moderate asthma
This trial looks at why airflow is limited in people with moderate-to-severe persistent asthma who are already on stable treatment. It may help researchers better understand what drives breathing trouble and how to target it.
Lakewood, CaliforniaAges 10–95 - NCT03839992Recruiting
Checks for hidden small airways blockage in cystic fibrosis
This trial looks for early, “hidden” breathing test abnormalities in people with cystic fibrosis who have normal routine lung test results. It may help researchers find blockage in smaller airways before it shows up on standard tests.
Lakewood, CaliforniaAges 5–40 - NCT03916302Recruiting
Pulmonary embolism registry study in Warsaw
This study keeps a registry (record) of people with a confirmed pulmonary embolism. Your information helps doctors better understand the condition and improve care.
WarsawAges 18 years+ - NCT06105242Recruiting
Sex differences in CTEPH heart function and recovery
This study looks at how CTEPH (a type of high blood pressure in the lungs caused by blood clots) affects heart function differently in men and women. It uses heart ultrasounds and pressure measurements to see if recovery after surgery differs by sex.
Murray, UtahAges 18 years+ - NCT05344209RecruitingPhase 2
Pembrolizumab plus or minus vaccine for advanced lung cancer
This Phase 2 trial studies pembrolizumab (an immune-boosting cancer medicine) alone or with an added investigational UV1 vaccine in people with advanced non-small cell lung cancer. It aims to see whether adding the vaccine improves safety and effectiveness, especially in tumors with high PD-L1 levels.
Drammen, AkershusAges 18 years+ - NCT06125041RecruitingPhase 2
Adebelizumab with chemo and radiation for advanced lung cancer
This trial tests a new drug called Adebelizumab (an immunotherapy) combined with chemotherapy and radiation for people with extensive stage small cell lung cancer. The goal is to see if this combination helps shrink tumors and improves survival.
Jinan, ShandongAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.