Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT07186296Recruiting
Emerald blood test study for new cancer diagnosis
This study is testing a blood test that looks for signs of lung, breast, colorectal, pancreatic, or ovarian cancer. If you have just been told you might have one of these cancers and haven't started treatment yet, this study may be an option to help learn more about your cancer from a simple blood draw.
Long Beach, CaliforniaAges 45 years+ - NCT07189806Recruiting
Asthma study tracking symptoms over 5 years
This study follows adults with mild, moderate, or severe asthma to better understand the condition. You'll attend regular check-ups at the clinic to monitor your lung function and symptoms over five years.
LondonAges 18 years+ - NCT07189455RecruitingPhase 3
Comparing ZG006 to chemotherapy for relapsed small cell lung cancer
This study compares a new drug called ZG006 against standard chemotherapy for people with small cell lung cancer that has come back after prior treatment. The goal is to see if ZG006 works better or has fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07191860Recruiting
Coated balloon for non-cancerous airway narrowing
This trial tests a special balloon coated with a medicine (paclitaxel) to open narrowed windpipes. It is for people whose windpipe is blocked by scar tissue from a ventilator, transplant, or other non-cancer causes, not from cancer.
Baltimore, MarylandAges 22 years+ - NCT07189871RecruitingPhase 1/Phase 2
Targeted radiation therapy for advanced solid tumors
This study tests a new radioactive treatment (177Lu-BetaBart) for people with certain advanced solid tumors that have stopped responding to standard treatments. It aims to see if this targeted therapy can slow or stop tumor growth.
Dothan, AlabamaAges 18 years+ - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT07189078Recruiting
Comparing intubation methods for patients with low blood oxygen
This study tests two different ways to place a breathing tube in patients who are in intensive care with very low oxygen levels and need help breathing. The goal is to find which method is safer and works better for patients like you.
AngersAges 18 years+ - NCT07191002Recruiting
Choosing the right double-lumen tube size for lung surgery
This trial tests different formulas to predict the correct size of a double-lumen breathing tube used during lung surgery. It aims to make anesthesia safer and more effective for patients.
AnkaraAges 18–80 - NCT06945614RecruitingPhase 1
Xenon gas for brain inflammation safety study
This study tests an inhaled gas called xenon to see if it can safely reduce brain inflammation. The study is for healthy volunteers aged 55-75 to check safety and early signs of benefit.
Boston, MassachusettsAges 55–75 - NCT06944782Recruiting
Can mouth muscle tests help diagnose sleep apnea?
This study tests a new device that measures muscle activity in your mouth to diagnose sleep apnea—without needing to spend the night in a lab. If you've already had a sleep test showing either no sleep apnea or moderate to severe sleep apnea, and you're not using CPAP daily, you may be able to help.
San Diego, CaliforniaAges 18–80 - NCT07187193RecruitingPhase 2
Low-dose chemo plus thalidomide for untreated LCH
This trial tests a combination of two drugs, low-dose cytarabine and thalidomide, for adults with Langerhans cell histiocytosis (LCH) that has not been treated before with systemic therapy. The goal is to see if this treatment is safe and effective for people with LCH in multiple body areas or multiple spots in one system.
BeijingAges 18–70 - NCT07191509Recruiting
Understanding breathing after tracheostomy removal
This study looks at how your breathing changes after removing a tracheostomy tube, using a valve and simple breathing tests. It may help doctors better plan your recovery.
BeijingAges 18 years+ - NCT07192575Recruiting
Preventing lung problems after laparoscopic liver surgery
This trial tests if special breathing exercises before surgery can help prevent lung complications after laparoscopic (keyhole) liver surgery. It may benefit you by reducing your risk of pneumonia or other breathing issues after the procedure.
KuopioAges 18 years+ - NCT07185659Recruiting
Walking Exercise for COPD Patients
This study looks at whether a walking exercise program can help people with COPD (a lung condition) feel better and breathe easier. It is designed for people who are currently in the hospital and can do gentle walking.
New Taipei City, Xindian Dist.Ages 40–100 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07184528Recruiting
Endobronchial valves and blood patch for air leaks
This trial tests a two-step procedure that uses small valves and a blood patch to close persistent air leaks in the lung. It could be an option for people who cannot have or don't want surgery.
Boston, MassachusettsAges 18 years+ - NCT07187206RecruitingPhase 3
Fetoscopic surgery for severe diaphragmatic hernia
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
Cincinnati, OhioAges 18–50 - NCT07186699Recruiting
Lung and esophageal cancer care study for people with alcohol or substance use history
This study talks with people who have been treated for lung or esophageal cancer and have a history of alcohol or substance use. The goal is to learn about their experiences to improve cancer care and support.
Los Angeles, CaliforniaAges 18 years+ - NCT07192458RecruitingPhase 2
High vs. Standard Dose Flu Vaccine in Lung Transplant
This study compares a high-dose flu vaccine to the standard dose in lung transplant recipients. It aims to see if a higher dose gives better protection against the flu.
Nashville, TennesseeAges 18 years+ - NCT07191314Recruiting
Long-term study of a nasal airway for sleep apnea
This study is for people who already finished a previous study using a device called a nasopharyngeal airway (a small tube placed in the nose to help with breathing during sleep). It will check how well the device works over a longer time.
Ann Arbor, MichiganAges 18 years+ - NCT07189260Recruiting
Breathing exercises to prevent pneumonia after hip fracture
This trial tests whether simple breathing exercises before and after surgery can help prevent pneumonia in people with hip fractures. It is not a medication study—you'd use a small device to help you breathe deeply.
CopenhagenAges 18 years+ - NCT07185035RecruitingEarly Phase 1
Testing natural killer cells for leftover lung nodules
This trial is testing a new treatment using your own immune cells (called NK cells) to fight leftover high-risk lung nodules that cannot be surgically removed. It is for people who have already had some cancerous nodules removed and are looking for another option.
NanjingAges 18–70 - NCT07192900RecruitingPhase 1
Fast TILs for metastatic cancer with pleural disease
This trial tests a new therapy using your own immune cells (called TILs) to treat cancer that has spread to the lining of the lungs. The goal is to see if these cells can shrink tumors and help you feel better.
Pittsburgh, PennsylvaniaAges 18–79 - NCT07191171Recruiting
Gut bacteria drugs and immunotherapy in lung cancer
This study looks at whether certain drugs (like antibiotics or other gut-bacteria-affecting medications) influence how well immunotherapy works for advanced non-small cell lung cancer. It may help find ways to improve treatment outcomes.
StrasbourgAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.