Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05704881Recruiting
Using breath CO2 levels to judge COPD flare severity in ER
This study measures an easy breathing signal called end-tidal carbon dioxide (a CO2 reading from your exhaled breath) to help judge how severe a COPD flare is. It may help doctors decide how closely you need monitoring and treatment during emergency care.
Grenoble, IsèreAges 18 years+ - NCT05704920Recruiting
AI-based support for lung cancer screening scans
This trial tests whether using artificial intelligence (computer pattern-recognition) with lung screening images can help identify people who may have lung cancer earlier. It’s meant for people at higher risk because of their smoking history, who can follow the screening steps.
Nice, Alpes-maritimesAges 18–80 - NCT05708300Recruiting
Testing how mepolizumab works for people with nasal polyps
This study looks at blood and other measures (biomarkers) to understand how well mepolizumab helps people with nasal polyps, with or without asthma. It aims to find response clues that could help personalize treatment in the future.
Thessaloniki, ExochiAges 18 years+ - NCT05708443Recruiting
Exercise training to improve walking and daily activities in COPD
This trial studies whether doing a combination of endurance exercises can help people with COPD walk better and do everyday activities with less limitation. It compares an exercise approach aimed at improving walking function and daily movement.
Lumezzane, BresciaAges Any age - NCT05713006RecruitingPhase 1/Phase 2
Alectinib drug handling study for ALK-positive advanced lung cancer
This early-phase trial studies how alectinib (an ALK-blocking medicine) moves through the body and how it’s tolerated in people with advanced non-small cell lung cancer (NSCLC) that has an ALK rearrangement. You may be considered if you have ALK-positive, recurrent or advanced disease and have already had specific prior treatments.
Mexico City, Mexico CityAges 18 years+ - NCT05715229RecruitingPhase 2
Blood test–guided treatment choice for advanced lung cancer
This Phase 2 study tests how results from blood cancer DNA tests (ctDNA) can help choose the best immune therapy approach for newly diagnosed, advanced lung cancer. It aims to improve outcomes by matching treatment decisions to a patient’s immune and blood test “profile.”
Washington D.C., District of ColumbiaAges 18 years+ - NCT05717192Recruiting
Bronchoscopy treatment to shrink severe emphysema using heat
This trial studies a bronchoscopy procedure that uses heat (thermoablation) to reduce over-inflated lung tissue in people with severe emphysema. If you qualify, it aims to improve breathing and walking ability after trying standard treatments first.
BerlinAges 40–75 - NCT05719415Recruiting
Testing balloon treatment effects on lung blood-vessel surface area
This study looks at how a procedure called balloon pulmonary angioplasty changes measurements in lung blood vessels in people with chronic thromboembolic pulmonary hypertension. It may help doctors understand what changes the treatment makes and why.
Montreal, QuebecAges 18–75 - NCT05719779Recruiting
Oral device trial for snoring and sleep apnea in throat cancer
This trial tests whether a custom mouth (mandibular advanced) device can reduce snoring and breathing pauses during sleep in people with oropharyngeal (throat) cancer. It also looks at how well you tolerate the device and whether it helps with sleep symptoms.
Montreal, QuebecAges 18–65 - NCT05720780Recruiting
Music-based rehab training for people with COPD and low oxygen
This trial studies whether combining music with exercise training can improve breathing ability and exercise tolerance in people with COPD and chronic low oxygen. It also looks at whether the program is safe for people who are stable on long-term oxygen.
Telese Terme, BeneventoAges 40–85 - NCT05723445Recruiting
Low glycemic diet test for diabetes and body changes in CF
This trial studies whether a low glycemic load (a specific way of choosing carbohydrates) improves blood sugar control and body composition in adults with cystic fibrosis–related diabetes. It may help reduce blood sugar problems and support healthier weight and body measurements.
Boston, MassachusettsAges 18–70 - NCT05724264Recruiting
Lung cancer screening using CT and blood marker tests
This study tests whether combining low-dose chest CT scans with blood “biomarker” tests can help find lung cancer earlier in people at higher risk. You may be asked to have scans and blood tests and then attend follow-up visits over time.
SingaporeAges 50–80 - NCT05724004Recruiting
Alectinib then targeted radiation for ALK-positive lung cancer
This trial tests giving alectinib first, then adding targeted radiation to remaining spots of cancer in people with ALK-rearranged advanced non-small cell lung cancer. It aims to control the cancer after an initial response and help keep disease from progressing.
StockholmAges 20 years+ - NCT05724745Recruiting
3D lung breathing test during MRI versus standard spirometry
This study compares a new 3D MRI-based breathing test with the usual breathing test called spirometry. It may help doctors measure lung function more precisely in healthy people and in people with asthma, COPD, or after a double lung transplant.
Orsay, FranceAges 18–90 - NCT05728242Recruiting
Gastric ultrasound to guide anesthesia for fracture surgery
This trial studies using a bedside ultrasound scan of the stomach (“gastric ultrasound”) to help guide anesthesia decisions during surgery for traumatic fractures. It may help reduce stomach-related anesthesia risks in the operating room by better assessing stomach contents.
IstanbulAges 18–90 - NCT05730088Recruiting
Helping COPD patients avoid hospital visits with home nursing support
This trial tests whether adding several nursing check-ins and coaching (using home oxygen and regular contact) can help people with severe COPD avoid going back to the hospital. It uses phone or internet tools to support care at home.
KonyaAges 18 years+ - NCT05731024Recruiting
Closed-loop breathing control vs standard care for kids in ICU
This study compares a computerized “closed-loop” system that helps match breathing support to a child’s needs versus usual (standard) breathing control. It’s for critically ill children on a breathing machine, aiming to improve synchronization between the child and the ventilator.
AydinAges 1 month–18 years - NCT05731427Recruiting
Study on what drives bronchiectasis worsening
This study looks at why bronchiectasis gets worse over time. It may help doctors understand the disease better and find better ways to monitor or treat it.
Guiyang, GuizhouAges 18 years+ - NCT05732883RecruitingPhase 2
Dexamethasone after thyroid surgery to help voice and calcium
This Phase 2 study tests whether giving dexamethasone (a steroid medicine) around the time of total thyroid surgery can improve voice outcomes and reduce low-calcium problems. It may help people avoid hoarseness and symptoms of hypocalcemia after surgery, especially those at risk.
Hong KongAges 18 years+ - NCT05733104Recruiting
Study of Zavicefta safety after it’s used in Korea
This study looks at how the antibiotic Zavicefta is doing after it’s been approved and used by doctors in Korea. It may help confirm its safety and appropriate use for certain serious infections.
Seoul, Gangnam-guAges 3 months+ - NCT05732974Recruiting
Using a computer tool to find lung cancer relapse risk
This study uses a machine-learning computer method to identify people with early-stage lung cancer who have a higher risk of the cancer coming back after surgery. If you qualify, your information may help researchers improve how doctors predict relapse and plan follow-up care.
ToulouseAges 18 years+ - NCT05733000RecruitingPhase 2
CPI-613 plus hydroxychloroquine with chemo for advanced solid tumors
This trial tests a drug called CPI-613 (devimistat) combined with hydroxychloroquine along with either 5-fluorouracil or gemcitabine chemo. It’s for people with advanced cancers that have stopped responding to standard treatments, aiming to shrink tumors and slow cancer growth.
Chicago, IllinoisAges 18 years+ - NCT05734261Recruiting
Lung function test in children using metacholine
This trial studies how well a special breathing test (forced oscillations) works during a methacholine challenge in children. It may help doctors better measure breathing sensitivity and guide treatment decisions.
MontpellierAges 6–16 - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.