Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05679349Recruiting
Help your clinic improve lung cancer screening for smokers
This study helps primary care clinics reach people who have a long smoking history so they can get lung cancer screening at the right time. It may help you (and others) get reminders and outreach to make screening easier to schedule.
Philadelphia, PennsylvaniaAges 50–77 - NCT05681780RecruitingPhase 1
CD40L-treated immune cells for advanced lung cancer with certain gene changes
This Phase 1 study tests a lab-made immune cell treatment (TIL) boosted with CD40L, plus nivolumab, for stage IV or returning non-small cell lung cancer with specific gene changes (EGFR, ALK, ROS1, or HER2). It aims to help your immune system attack the cancer after it has grown despite standard treatments.
Tampa, FloridaAges 18 years+ - NCT05681962Recruiting
Improving breathing support during flexible bronchoscopy
This trial studies how to give oxygen and breathing support during a flexible bronchoscopy (a camera test through the airways). It may help make the procedure safer and more comfortable by refining the way oxygen is managed during the test.
CatanzaroAges 18 years+ - NCT05685628Recruiting
Test cinnamon dressing for smell and comfort of wounds
This study checks whether a cinnamon anti-odor dressing improves quality of life for adults with very smelly wounds. Researchers will compare how the dressing affects comfort and smell, and how well patients can live day to day while treating the wound.
Vaux-le-Pénil, FranceAges 18 years+ - NCT05686434RecruitingPhase 2
Osimertinib after surgery for early-stage EGFR-mutated lung cancer
This trial tests osimertinib (a targeted pill) given after surgery to help prevent early-stage lung cancer from coming back. It’s for people with fully removed, high-risk stage I non-small cell lung cancer that has specific EGFR gene changes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05688488RecruitingPhase 1/Phase 2
Curcumin to help prevent vocal cord scar adhesions after surgery
This trial tests whether curcumin (a natural compound) can reduce scar-like “adhesions” that can form between both vocal cords after endoscopy surgery. If you’re having a procedure on both vocal cords, this could help lower the chance of postoperative sticking and related voice problems.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05689619Recruiting
Silibinin after one brain metastasis surgery for lung or breast cancer
This trial studies silibinin, a natural substance, to help prevent brain metastasis from coming back after surgery. It is for people with lung (NSCLC) or breast cancer who have exactly one small brain metastasis that is fully removed and has a specific lab marker in the brain tissue.
GenovaAges 18–70 - NCT05692635RecruitingPhase 2
Brain MRI checks to prevent lung cancer brain symptoms
This trial tests whether doing scheduled brain MRI scans can lower the chance that lung cancer later causes symptomatic brain metastases (tumors that cause symptoms in the brain). If you’re eligible, you’ll get brain MRI surveillance at a specific time after starting radiation.
Winston-Salem, North CarolinaAges 18 years+ - NCT05693363Recruiting
Scan lung tissue with a PET-CT during thoracic surgery
This study tests whether a special imaging scan using a radioactive sugar (18F-FDG) can help doctors better examine lung cancer tissue during thoracic surgery. You may be offered the scan around the time of your operation to help researchers learn how well it works.
GhentAges 18 years+ - NCT05694806Recruiting
CT scan study for blood cancers with a chest mass syndrome
This study looks at how CT scan findings in the chest (mediastinum) can relate to outcomes for people with blood cancers who have mediastinal mass syndrome. It may help doctors better understand which scan features matter most when deciding care in the ICU.
ToulouseAges 16 years+ - NCT05695131Recruiting
Testing virtual reality speech therapy for adults
This study checks whether a virtual reality (VR) version of a speech-language therapy program is practical and works the way it should. You might benefit by getting speech therapy in a new, technology-based format, and helping researchers confirm it is safe and feasible.
Edmonton, AlbertaAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05696782RecruitingPhase 2
Durvalumab after chemoradiation for stage III lung cancer
This trial tests giving durvalumab (an immune therapy) soon after standard chemotherapy and radiation for stage II–III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this “quick start” approach improves outcomes compared with waiting longer to begin durvalumab.
Winston-Salem, North CarolinaAges 18 years+ - NCT05699213Recruiting
MRI and blood tests for lung nodules found on screening
This study looks at whether MRI scans and blood-related biomarkers can help better understand lung nodules found during routine lung cancer screening. It may help doctors decide which nodules need closer follow-up versus less intensive monitoring.
Los Angeles, CaliforniaAges 50 years+ - NCT05701787Recruiting
Study of lung cancer with rare gene changes
This trial looks at the “molecular landscape,” meaning the specific gene changes driving your lung cancer, for people whose non-small cell lung cancer (NSCLC) has rare mutations. The goal is to better understand what those rare changes mean and how they could guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05701514Recruiting
Test in babies with a prenatal lung cyst found on scans
This trial is for newborns who are found before birth to have a congenital lung cyst (CPAM) and who stay symptom-free. It tests an approach for babies with certain CPAM features to see if it’s safer and/or more effective than standard care.
Nijmegen, GelderlanfAges 1 month–1 year - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05703516Recruiting
Study of Tabrecta for NSCLC with exon 14 skipping
This study follows people in South Korea who have a specific lung cancer genetic change called “exon 14 skipping” and are going to take Tabrecta (capmatinib). It helps collect real-world safety and results for using this medicine under routine care.
Daegu, Dalseo guAges 18–100 - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT05704166RecruitingPhase 2
Pirfenidone to prevent lung injury after breast radiation
This trial tests whether pirfenidone, a medication, can prevent acute lung injury caused by radiation therapy in people with breast cancer. You may be randomly assigned to pirfenidone or a placebo (inactive pill) to see which better protects the lungs during and after radiation.
Fuzhou, FujianAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.