Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100 - NCT05765877RecruitingPhase 2
Study drug before surgery for ALK or ROS1 lung cancer
This Phase 2 trial tests WX-0593 given before surgery for certain types of lung cancer that have ALK or ROS1 gene changes. The goal is to shrink or control the cancer ahead of the operation and see how well the treatment works and is tolerated.
Jinan, ShandongAges 18 years+ - NCT05766774Recruiting
Diet study for adults with cystic fibrosis and high sugar intake
This trial studies whether changing eating habits—especially added sugar intake—affects health in adults with cystic fibrosis. It may help by testing a diet approach aimed at better outcomes related to metabolism and overall health.
Atlanta, GeorgiaAges 18 years+ - NCT05766800RecruitingPhase 2
PD-1 plus chemotherapy before surgery for advanced lung cancer
This trial studies whether giving a PD-1 antibody together with standard chemotherapy before surgery can improve outcomes for people with stage IIIB–IIIC non-small cell lung cancer. It aims to shrink or control the cancer and make treatment before surgery more effective.
ShanghaiAges 18 years+ - NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05768399Recruiting
Study uses blood or test markers to track childhood asthma
This study looks for biological “markers” that may help explain why asthma starts and how it changes over time in children. It may help your child’s doctors understand asthma better, especially for diagnosis or tracking.
Chongqing, Chongqing MunicipalityAges 4–12 - NCT05768178RecruitingPhase 2/Phase 3
Vemurafenib plus cobimetinib for BRAF-mutant cancers
This trial tests whether combining two targeted cancer medicines—vemurafenib and cobimetinib—can treat adults whose tumors have a specific “BRAF V600” mutation. You may be screened with blood tests and a tissue biopsy before starting treatment.
BelfastAges 18 years+ - NCT05769140Recruiting
Study how high altitude affects heart and breathing measures
This study looks at how exposure to high altitude changes measurements related to your heart and breathing. It may help scientists better understand health effects of altitude so they can improve safety and care.
Courmayeur, AostaAges 18 years+ - NCT05772013RecruitingPhase 4
Checking azithromycin prevention for COPD flare-ups
This Phase 4 study looks at optimizing how people with COPD take azithromycin to reduce flare-ups (exacerbations). If you already take azithromycin regularly, the trial may test ways to improve how it’s used safely.
CambridgeAges 40 years+ - NCT05774093Recruiting
Study how COVID immunity affects reinfection risk
This study looks at how well COVID-19 protection (immune barrier) holds up over time and how likely people are to get reinfected. It may help researchers understand who is more at risk after prior infection and why.
Guangzhou, GuangdongAges Any age - NCT05775939Recruiting
PET/CT scan study to track heart damage from cancer radiation
This study uses a special scan (PET/CT) to look for early heart (cardiac) injury caused by radiation treatment for lung or esophageal cancer. If you may be at higher heart risk from your planned radiation dose, the scan may help researchers better measure that damage over time.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05777278RecruitingPhase 1/Phase 2
Savolitinib plus docetaxel for advanced lung cancer with high MET
This trial studies savolitinib (an oral MET-targeted medicine) combined with docetaxel (an IV chemotherapy) in people with advanced non-small cell lung cancer (NSCLC) whose tumor has high MET activity. It’s designed to see if this combination can shrink tumors or control the cancer after the first standard treatment.
Guangzhou, GuangdongAges 18 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT05782478Recruiting
Ultrasound test to guide care for sudden breathing trouble
This trial studies whether a quick bedside ultrasound exam (done in the emergency department) adds useful information when people arrive with sudden breathing difficulty. It may help clinicians choose the right next steps faster and safer.
Helsingborg, Skåne CountyAges 18 years+ - NCT05783908Recruiting
Self-guided breathing help during MRI-guided radiotherapy for moving tumors
This study tests whether a self-guidance approach for breathing can improve radiotherapy sessions when the tumor moves during breathing and is treated with an MRI-guided machine. It may help make treatments more accurate and easier to follow during each session.
Dijon, Côte d'OrAges 1.5 years+ - NCT05783869Recruiting
Bronchiectasis and heart-related conditions study
This study looks at people who have bronchiectasis (long-term lung damage that causes ongoing infections) and focuses on how heart-related conditions may affect outcomes during the study. It may help doctors better understand what to monitor and how to manage risk in people with both lung and heart issues.
AsyutAges 18–80 - NCT05784922Recruiting
Lung cancer screening support for eligible smokers
This study aims to improve and promote lung cancer screening for people at higher risk who may face barriers. You may be asked to share your experiences through surveys or focus-group style activities to help make screening more equitable.
Boston, MassachusettsAges 50–80 - NCT05785026Recruiting
Menthol to reduce breathlessness in COPD and healthy adults
This trial tests whether menthol helps with breathlessness (dyspnea) during exercise. You may be asked to do breathing and exercise tests, and to use menthol under study supervision to see if symptoms improve.
LeuvenAges 18 years+ - NCT05785065RecruitingPhase 2
Mycophenolate for early lung scarring in systemic sclerosis
This Phase 2 study tests whether mycophenolate mofetil (MMF) can slow or improve early, mild lung scarring in people with systemic sclerosis. It’s meant for systemic sclerosis patients who have lung involvement on a CT scan but still have good breathing test results.
Montreal, QuebecAges 18 years+ - NCT05785741RecruitingPhase 1/Phase 2
DB-1310 for advanced solid tumors after standard treatment fails
This early-phase study tests DB-1310 in people with advanced or metastatic solid cancers that have come back or worsened after standard treatments. It aims to find the safest dose and whether it can help shrink tumors or slow cancer growth.
Sacramento, CaliforniaAges 18 years+ - NCT05786716RecruitingPhase 2/Phase 3
Trastuzumab plus pertuzumab for HER2-mutated cancers
This trial tests whether combining trastuzumab and pertuzumab can treat cancers that have HER2 amplification or an activating HER2 mutation. It looks at people ages 12 and older, and may include both children/teens and adults, using the study drug based on their HER2 test results.
BelfastAges 12 years+ - NCT05787379Recruiting
Care program for Veterans with long-lasting COVID symptoms
This trial tests a care approach for Veterans who have long-COVID—aiming to improve symptoms and follow-up care through participating VA clinicians. You may be included if you are a Veteran with long-COVID and can be seen by a participating clinician soon, unless you had severe COVID requiring ICU care.
East Orange, New JerseyAges Any age - NCT05786924RecruitingPhase 1/Phase 2
Targeted cancer drug study for RAS/RAF mutation-positive tumors
This Phase 1/2 study tests S241656 (a targeted cancer medicine) in people whose cancers have certain “RAS/RAF” gene changes. It may help shrink tumors or control cancer growth, and also finds the safest dose and best way to use the drug.
Gilbert, ArizonaAges 18 years+ - NCT05789082RecruitingPhase 1/Phase 2
Divarasib for untreated lung cancer with KRAS G12C
This trial studies divarasib to see if it is safe and can shrink or control advanced lung cancer. Participants must have a KRAS G12C mutation and have not had prior treatment for their advanced disease.
Duarte, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.