Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT05792280Recruiting
AI-assisted endoscopic ultrasound for chest (mediastinal) imaging
This study tests a new computer (deep-learning) system to help interpret images from an endoscopic ultrasound exam of the chest area. It may help make the scan information more consistent and useful for diagnosis.
Changsha, HunanAges 18–80 - NCT05793151Recruiting
Guided care to start cancer treatment on time after surgery
This trial tests a navigation program (help from a care coordinator) versus usual care to help people start the recommended “next-step” treatments (like radiation, sometimes with chemo) on time after surgery. It’s for certain stages of squamous cell cancer in the head and neck area where late treatment could matter.
St Louis, MissouriAges 18 years+ - NCT05795465RecruitingPhase 2
Study drug for people with acute respiratory distress syndrome
This Phase 2 trial tests GEn-1124 to see if it can improve outcomes in people with acute respiratory distress syndrome (ARDS). You may be eligible if the study drug can be started very soon after ARDS is diagnosed and if you meet the safety and health requirements.
Washington D.C., District of ColumbiaAges 18–85 - NCT05795257Recruiting
Studying lung immune cells and gut microbes in ARDS
This trial studies how immune cells in the lungs and gut microbes (your microbiome) change during ARDS and how these changes relate to your outcomes. It may help researchers better predict and treat ARDS by learning what’s going on in the lungs and body systems.
HvidovreAges 18 years+ - NCT05796505Recruiting
Community outreach to improve vaccine acceptance in prisons
This study tests community engagement approaches to help people in prison feel more comfortable accepting vaccines. It will focus on people in regular housing areas, and it may help increase vaccine willingness through trusted local outreach.
Schwenksville, PennsylvaniaAges 18 years+ - NCT05797493Recruiting
Test blood and immune markers in extensive-stage small cell lung cancer
This study looks at immune-related blood/tissue markers to understand disease activity in people with extensive-stage small cell lung cancer after standard upfront treatment. If your cancer fits the pattern they’re studying, it may help researchers improve how future treatments are matched to patients.
RomeAges 18 years+ - NCT05797649Recruiting
Test a pleural fluid blood marker to tell heart failure vs others
This study checks whether a substance called NT-proBNP in pleural fluid can better identify if fluid around the lung is caused by heart failure. If you fit, the results may help doctors choose faster, more accurate diagnosis for your pleural effusion.
Hong Kong, New TerritoriesAges 18 years+ - NCT05799664Recruiting
Radiofrequency treatment for COPD using a breathing tube
This trial tests whether a special radiofrequency treatment delivered through a bronchoscope (a thin camera tube) is safe and works better than standard care for people with COPD. It focuses on people with moderate-to-severe COPD symptoms who can follow study visits and tests.
Chengdu, SichuanAges 40–75 - NCT05800340RecruitingPhase 2
Immunotherapy before surgery for certain rare lung cancer mutations
This Phase 2 study tests an immunotherapy treatment given before surgery for people with stage IIB to IIIB non-small cell lung cancer (NSCLC) that has specific rare “driver” gene changes. The goal is to shrink the cancer and improve outcomes by treating it earlier with the immune system.
Guanzhou, GuangdongAges 18 years+ - NCT05800587RecruitingPhase 2
Reduced-dose chemotherapy for advanced lung cancer
This trial studies a lower (reduced) dose of chemotherapy in people with advanced lung cancer who may not tolerate standard treatment. It aims to see if the treatment still works while being safer for “compromised” patients.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05802186Recruiting
AI-guided radiation plan for lung cancer tumors
This study uses an AI tool to help plan how doctors deliver focused radiation to lung tumors. It may help make radiation targeting more precise and support treatment safety for people with primary or limited metastatic lung cancer.
Chicago, IllinoisAges 18 years+ - NCT05802264RecruitingPhase 1
Inhaled amphotericin B for healthy volunteers and cystic fibrosis
This early-phase study tests how different doses of an inhaled medicine (amphotericin B) work and are tolerated. It includes healthy adults and people with cystic fibrosis (CF) to see if the dose schedule is safe and potentially beneficial.
Canberra, Australian Capital TerritoryAges 16 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05805319Recruiting
Food intervention for people with lung cancer on immunotherapy
This trial studies whether a specific diet can help people with non-small cell lung cancer who are receiving immunotherapy (a standard cancer treatment). It mainly checks whether participants can follow the diet plan and tolerate the food changes safely.
Montreal, QuebecAges 18 years+ - NCT05804786Recruiting
Study of bronchoscopy to diagnose lung spots
This study follows people who have lung “spots” that look like possible lung cancer and need a biopsy to figure out what they are. It uses a guided breathing-tube procedure to safely collect tissue so doctors can make a diagnosis.
DaeguAges 19 years+ - NCT05805631RecruitingPhase 2
Pemetrexed into spinal fluid for EGFR-mutant lung cancer spread to brain lining
This Phase 2 trial tests giving pemetrexed directly into the spinal fluid to treat cancer that has spread to the brain’s and spinal cord’s lining (leptomeningeal metastasis). It is for people with EGFR-mutant non-squamous lung cancer whose disease progressed after osimertinib, and who may benefit from a targeted treatment delivered to the area affected in the brain lining.
Taipei, TaiwanAges 20 years+ - NCT05807399RecruitingPhase 2
Step2c trial for new, drug-susceptible lung TB
This Phase 2 study tests treatment for people with newly diagnosed, drug-susceptible pulmonary (lung) tuberculosis (TB). It aims to see whether the study treatment works well and is safe for curing TB.
LambarénéAges 18–65 - NCT05811780Recruiting
Record of devices that support organs outside the body
This registry collects information about people who are treated with a machine that supports an organ outside the body. The goal is to better understand how these devices are used and may help improve care over time.
Freiburg im BreisgauAges Any age - NCT05813223RecruitingEarly Phase 1
Gefapixant to study brain activity in chronic cough
This early study tests whether gefapixant changes brain activity related to cough in people with chronic cough that hasn’t improved with usual treatments. It may help researchers understand why chronic cough happens and how to better treat it.
Parkville, VictoriaAges 18–65 - NCT05816954Recruiting
Imaging test to predict lung injury risk in ARDS
This study looks at scan images to better predict the risk of a serious lung complication (barotrauma) in people with ARDS. It may help doctors choose safer treatment strategies in the ICU.
Catanzaro, CalabriaAges 18 years+ - NCT05818319Recruiting
Tracking kidney urine effects after a short pause in CF therapy
This study checks how a common cystic fibrosis (CF) medicine affects urine markers after briefly stopping it and then restarting. The goal is to better understand whether the treatment shift changes kidney-related signals in people with CF.
Aarhus C, Central JutlandAges 18 years+ - NCT05819346Recruiting
Digital lifestyle program for lung cancer survivors
This trial tests a phone/tablet-based lifestyle program for people who have finished lung cancer treatment. It may help survivors improve health and daily habits after non-small cell lung cancer.
BarmelweidAges 18 years+ - NCT05819385Recruiting
Study of lung scarring in immune diseases
This is an observational (non-treatment) study that collects information about how interstitial lung disease (lung scarring) happens in people with certain autoimmune or immune-related conditions. It uses patient interviews or existing medical records to better understand the pattern and causes, which may help future care.
Mexico CityAges 18 years+ - NCT05819996Recruiting
Study effects of tetrachloroethylene in Martinsville, Indiana
This study looks at people living in Martinsville, Indiana to better understand the impact of tetrachloroethylene exposure (a chemical found in some environments). If you’re an adult resident, you may be able to join and help researchers learn how exposure affects health.
West Lafayette, IndianaAges 18–99
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.