Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT06168032Recruiting
COVID-19 vaccine for lung cancer patients
This trial is testing how well the COVID-19 vaccine works for people with lung cancer to prevent another infection. It also looks at certain biomarkers in your blood that might help predict your body's immune response.
BeijingAges 18 years+ - NCT04442711Recruiting
Study of worsening lung symptoms in people with IPF
This study looks at people with idiopathic pulmonary fibrosis (IPF) who are currently having a sudden worsening of breathing symptoms. It may help doctors better understand what happens during these flare-ups and how to manage them.
Hellerup, CopenhagenAges 18 years+ - NCT05761028RecruitingPhase 2/Phase 3
CM310 for moderate to severe asthma despite current inhalers
This study tests CM310 to see if it can improve asthma in people with moderate to severe asthma who are still having uncontrolled symptoms and severe flare-ups despite regular inhaler treatment. You may be eligible if your lung function and asthma control tests fit the study limits and you’ve had a recent severe exacerbation.
Beijing, BeijinAges 12–75 - NCT05689619Recruiting
Silibinin after one brain metastasis surgery for lung or breast cancer
This trial studies silibinin, a natural substance, to help prevent brain metastasis from coming back after surgery. It is for people with lung (NSCLC) or breast cancer who have exactly one small brain metastasis that is fully removed and has a specific lab marker in the brain tissue.
GenovaAges 18–70 - NCT07867730Recruiting
Breathing exercises help people on ventilators with stiff lungs
This study tests two breathing exercises, inspiratory muscle training and positive expiratory pressure, for people in the ICU on a breathing machine. It aims to see if these exercises can improve breathing and recovery for patients with restrictive lung disease.
IslamabadAges 18–60 - NCT07428785Recruiting
Measuring lung and blood volume in COPD
This study looks at how COPD affects the amount of air your lungs can hold and the total blood in your body. The goal is to better understand the disease, which may help improve future treatments.
CopenhagenAges 45–80 - NCT07872683Recruiting
Drinking carbohydrates before hip or leg surgery: maltodextrin vs sugar water
This study compares two drinks given before surgery—maltodextrin (a carbohydrate powder mixed with water) versus sugar water—to see which one keeps the stomach empty and reduces risks during surgery on the lower limbs. It may help older patients have a safer and more comfortable experience.
Denpasar, BaliAges 60 years+ - NCT05549635Recruiting
Database and blood sample registry for hypersensitivity pneumonitis
This trial is building a patient database and collection of samples from people with hypersensitivity pneumonitis (HP), a lung condition caused by breathing in an allergy-like trigger. Your information and samples may help researchers learn how HP is diagnosed and tracked over time.
Hellerup, CopenhagenAges 18 years+ - NCT07869043RecruitingPhase 3
Study of tilrekimig for people with severe asthma
This study tests an investigational medicine called tilrekimig for people with severe asthma that is not well controlled. The goal is to see if it can reduce asthma attacks and improve breathing.
Pittsburgh, PennsylvaniaAges 12–80 - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT07854210Recruiting
High-flow nasal oxygen versus non-invasive ventilation for COPD
This trial compares two breathing support methods for people hospitalized with COPD and mild-to-moderate carbon dioxide retention. It aims to see if high-flow nasal oxygen is as effective as the standard mask-based ventilation.
Al Mansurah, Dakahlia GovernorateAges 40 years+ - NCT07861230Recruiting
Tongue study in children with sleep-disordered breathing
This study looks at the tongue in children aged 4 to 17 who have sleep-disordered breathing (like snoring or pauses in breathing during sleep). The goal is to understand how the tongue might be related to these sleep problems, which could lead to better treatments.
LiègeAges 4–17 - NCT05095090Recruiting
Study of hospital patients with breathing problems
This study looks at patients admitted to the hospital with acute breathing issues or those with ongoing lung conditions. It aims to better understand these conditions and may help improve future care.
LeicesterAges 18–90 - NCT04623463Recruiting
Exercise and how it affects sleep apnea severity
This study looks at whether regular physical activity can make obstructive sleep apnea (OSA) less severe. It focuses on people who are not yet receiving OSA treatment and checks changes in severity over time.
GrenobleAges 18–80 - NCT06184542RecruitingPhase 1
New DTaP vaccine safety trial for children
This trial tests a new combined vaccine for diphtheria, tetanus, and whooping cough (pertussis) in children of different ages. It aims to see if the vaccine is safe and how well it works, helping to protect against these serious diseases.
Dazhou, SichuanAges 2 months–6 years - NCT06192849RecruitingPhase 2
Furmonertinib after surgery for EGFR 20 insertion lung cancer
This trial tests a targeted pill (furmonertinib) to prevent your lung cancer from coming back after surgery. It is for people with a certain genetic change in their tumor (EGFR exon 20 insertion) and stage IB, II, or IIIA disease.
Chengdu, SichuanAges 18 years+ - NCT06189820RecruitingPhase 2
FAP protein as a marker for fibrotic lung disease
This trial is looking at a protein called FAP in the blood of people with fibrotic lung diseases. It aims to understand how this protein might be used as a marker to help doctors better diagnose and track these conditions.
BrusselsAges 18 years+ - NCT04938804Recruiting
One-time lung cancer screening with a low-dose chest CT
This study tests whether a one-time, low-dose chest CT scan can help find lung cancer early in certain people. You may be invited because of your age and location, and because you have not had recent related testing or symptoms.
Guangzhou, GuangdongAges 40–74 - NCT04235114RecruitingPhase 1/Phase 2
PET scan test for EGFR-positive cancers using an antibody tracer
This study tests a special PET scan agent (an antibody tracer) to help doctors see EGFR-positive cancers without needing invasive procedures. It is mainly for early testing (Phase 1/2) to understand how well it works for imaging.
Saskatoon, SaskatchewanAges 18–80 - NCT04459065RecruitingPhase 1/Phase 2
Imaging medicine to help find lung cancer during surgery
This trial tests a special imaging drug (IRDye800CW-nimotuzumab) that may help surgeons better see lung cancer tissue during planned lung surgery. Phase 1/2 looks mainly at safety and how well the imaging works to guide the operation.
Saskatoon, SaskatchewanAges 18–80 - NCT06197152Recruiting
RSV severity markers in hospitalized adults
This study looks for markers in the blood that can tell how serious an RSV infection might become. If you are hospitalized with RSV and have breathing symptoms, this trial will follow your recovery and test for clues about your illness.
CréteilAges 18 years+ - NCT06198309Recruiting
Predicting worsening COPD in severe patients
This study builds a tool to predict which COPD patients are likely to have worsening symptoms. It may help your doctor better manage your care if you have severe COPD.
Beijing, Beijing MunicipalityAges 40–85 - NCT07864207RecruitingPhase 1/Phase 2
Study of IDP-121 for small cell lung cancer that stopped responding to platinum
This trial tests a new drug, IDP-121, alone or with another chemo drug, for people with small cell lung cancer that came back after initial treatment. The goal is to see if it can shrink tumors and help people live longer.
BarcelonaAges 18 years+ - NCT06203249Recruiting
Exploring lung health and immune system in a rare muscle disease
This trial looks at how the immune system and tiny organisms in the lungs may affect a rare condition called anti-MDA5 positive dermatomyositis, which can cause serious lung disease. It may help doctors understand why some patients get worse quickly and how to better treat them.
Beijing, Beijing MunicipalityAges 18–100
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.