Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06865339RecruitingPhase 2
Radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.
The Bronx, New YorkAges 18 years+ - NCT06863168Recruiting
Cigarillo Education Messages for Black Young Adults
This study tests different messages to see what works best to help Black young adults avoid or cut back on cigarillo smoking. If you are between 18 and 30, identify as non-Hispanic Black, and are either open to trying cigarillos or only use them once in a while, this may be for you.
Philadelphia, PennsylvaniaAges 18–30 - NCT06812130Recruiting
Surviving the pediatric intensive care unit
This study looks at how children and their healthy siblings cope after a stay in the pediatric intensive care unit (PICU). It may help doctors and families better understand what support is needed during recovery.
Singapore, SingaporeAges 4 weeks–16 years - NCT06610838Recruiting
Long-term health effects of vaping nicotine
This study looks at how long-term e-cigarette use affects your health. Researchers will follow people who vape nicotine regularly to understand risks and benefits over time.
Madison, WisconsinAges 21 years+ - NCT06508008Recruiting
Safe sputum suction for stroke coma patients
This study tests a safer way to remove mucus from the airway in people who are in a coma after a stroke.
Nantong, JiangsuAges 20–90 - NCT06329817Recruiting
Regurgitation risk during intubation: semi-fowler vs supine
This trial compares two positions (semi-fowler and supine) during intubation to see which reduces regurgitation risk. It may help if you are an adult scheduled for intubation.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06088498RecruitingPhase 2
App to help reduce cravings to smoke
This trial tests a smartphone app that uses augmented reality to help people reduce smoking cravings. It may help if you recently quit smoking or currently smoke regularly.
Tampa, FloridaAges 18 years+ - NCT05868421Recruiting
Veteran coaching with a trusted person to quit smoking
This study tests whether involving a supportive family member or friend can help a veteran use smoking-quit treatment more effectively. If you’ve smoked recently and can name a trusted contact who will join, you may be able to participate.
Minneapolis, MinnesotaAges 18 years+ - NCT05759299Recruiting
Airway management study during anesthesia with intubation
This study observes how breathing tube placement (intubation) and other airway care are done during general anesthesia in the operating room and in other anesthesia settings. It may help improve airway management practices in different clinical environments, but you would typically not receive a new treatment as part of an experimental trial.
Dallas, TexasAges 18 years+ - NCT05743673Recruiting
SHAPE test to assess pre-surgery heart and lung risk
This trial studies a quick physical test (called the SHAPE test) given before surgery to help predict your risk of complications. It may help doctors choose safer care and monitoring based on your results.
New Haven, ConnecticutAges 60 years+ - NCT05479825Recruiting
Lung surgery planning without a tube, using X-ray guidance
This trial looks at a new way to plan a minimally invasive lung segment removal (“segmentectomy”) using live X-ray guidance, without using a chest tube (“tubeless”). It may help patients with certain small lung lesions (sometimes early lung cancer) get the surgery more precisely.
Jinan, Other (Non U.s.)Ages 18–85 - NCT05455723Recruiting
Test a new way to manage the breathing tube cuff during nasal intubation
This study tests a method for inflating and deflating the cuff on a breathing tube during nasal intubation (putting the tube through the nose) during an elective dental/maxillofacial surgery. It may help make the procedure safer and easier by improving how the cuff is managed.
IsmailiaAges 21 years+ - NCT04907136Recruiting
Testing health warning labels on e-cigarettes
This study tests whether different health warning labels on an e-cigarette device change how people understand risks and use the product. You may be able to help by trying labeled ENDS device options in a lab setting.
Miami, FloridaAges 21–35 - NCT03855722Recruiting
Remote heart protection before organ transplant
This study tests whether a simple treatment performed on the donor before organ removal can help transplanted organs work better. It may help patients receiving organs from eligible brain-dead donors at a specific hospital.
HelsinkiAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT02423070Recruiting
Study how donor genetic material behaves after lung or heart transplant
This study looks at how transplanted genetic material (DNA) changes and settles in the body after lung or heart transplant. It may help doctors understand transplant healing and improve future care for transplant recipients and candidates.
Washington D.C., District of ColumbiaAges 14–80 - NCT07226765RecruitingPhase 3
Weight-loss drug for sleep apnea without CPAP
This study tests a new weight-loss medication called maridebart cafraglutide against a placebo in people with moderate to severe obstructive sleep apnea who are not using a CPAP machine. The goal is to find out if weight loss can reduce symptoms like pauses in breathing during sleep.
Northridge, CaliforniaAges 18–99 - NCT06518057RecruitingPhase 2
Sparing memory during brain radiation for leptomeningeal metastases
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
San Francisco, CaliforniaAges 18 years+ - NCT05502653Recruiting
Study inflammation, lung function, and fungal movement in HIV
This study looks at how body inflammation and lung health relate to the movement of fungi in the body of people living with HIV. The goal is to better understand what factors may affect lung problems and fungal “translocation,” which may help future care.
Pittsburgh, PennsylvaniaAges 18–80 - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Little Rock, ArkansasAges 12 years+ - NCT06627647RecruitingPhase 3
Comparing two immunotherapy drugs for advanced lung cancer
This trial tests a new immunotherapy drug, rilvegostomig, against the standard pembrolizumab, both given with chemotherapy, as a first treatment for advanced non-squamous non-small cell lung cancer (NSCLC) that cannot be cured with surgery or radiation. It is for people whose tumors have high PD-L1 levels and do not have certain genetic mutations.
Mobile, AlabamaAges 18 years+ - NCT06772623RecruitingPhase 1/Phase 2
Study of telisotuzumab adizutecan plus immunotherapy for advanced lung cancer
This trial tests a new combination treatment for people with advanced non-squamous non-small cell lung cancer who haven't received prior therapy for advanced disease and don't have specific gene changes. The treatment includes an antibody-drug conjugate (telisotuzumab adizutecan) plus an immunotherapy drug (PD-1 checkpoint inhibitor) to see if it helps shrink tumors and improve outcomes.
Phoenix, ArizonaAges 18 years+ - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.