Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06315010RecruitingPhase 2
Repotrectinib for ROS1-positive lung cancer with brain spread
This clinical trial tests a new targeted therapy pill (repotrectinib) for people with ROS1-positive lung cancer that has spread to the brain. The pill is designed to enter the brain and attack cancer cells that other targeted treatments may not reach well.
GrazAges 18 years+ - NCT06317701Recruiting
Nerve stimulation for sleep apnea in overweight adults
This trial tests a nerve stimulation treatment for obstructive sleep apnea in people who are overweight and cannot tolerate CPAP. It focuses on how the treatment affects metabolism and weight.
Chicago, IllinoisAges 18 years+ - NCT06317805RecruitingPhase 4
Three-medicine start vs. two oral pills for new PAH
This study compares starting treatment with three medicines, including a continuous infusion (treprostinil), versus two oral medicines for people newly diagnosed with moderate-to-high risk pulmonary arterial hypertension (PAH). The goal is to see which approach improves heart function and symptoms more effectively.
LinzAges 18–70 - NCT06317831Recruiting
Let's get functional: function in interstitial lung disease
This trial tests a program to help people with interstitial lung disease improve their daily function and activity. It is for Portuguese speakers with any type of ILD who are otherwise stable.
AveiroAges 18 years+ - NCT06319482Recruiting
Testing a new sleep apnea therapy device
This study tests a new proactive therapy for people recently diagnosed with moderate or severe sleep apnea. It aims to see how well patients stick with the treatment outside of a sleep lab.
Halifax, Nova ScotiaAges 18–70 - NCT06320236Recruiting
Emergency study on testing for blood clots in the lungs
This study looks at how doctors decide to test for pulmonary embolism (a blood clot in the lungs) in the emergency department. It helps understand what factors lead to testing, which could improve care for future patients.
Hamilton, OntarioAges 18 years+ - NCT06321497Recruiting
Carbon dioxide removal to protect lungs during ARDS
This study tests a machine that removes carbon dioxide from your blood (called extracorporeal carbon dioxide removal or ECCO2R) to help protect your lungs from further damage while on a breathing machine. It may be an option if you have severe ARDS and your breathing machine settings are very high.
Frankston, VictoriaAges 18 years+ - NCT06322329Recruiting
RealMove Lung: Tracking tumor motion with MRI
This study uses a special MRI scan to measure how your lung tumor moves during breathing. The information may help doctors plan more precise radiation treatment (SBRT) for lung cancers located in the lower part of the lung.
StockholmAges 18 years+ - NCT06323213RecruitingPhase 3
Testing a new asthma medicine for severe asthma
This study tests an experimental drug called 610 for people with severe asthma that is not well-controlled with standard medicines. The goal is to see if adding 610 can improve asthma control and reduce flare-ups.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06323876Recruiting
Using CT scans to personalize treatment for pulmonary fibrosis
This study uses detailed CT scans to find better ways to treat idiopathic pulmonary fibrosis (IPF). It may help doctors choose the right treatment for each person.
Charlottesville, VirginiaAges 40–101 - NCT06325293Recruiting
Macrolide vs. placebo for mycoplasma pneumonia in children
This trial tests whether azithromycin (a macrolide antibiotic) is better than a placebo for treating mycoplasma pneumonia in children aged 3–17. If your child has pneumonia caused by mycoplasma, this study may help find the best treatment.
Aarau, Canton of AargauAges 3–17 - NCT06474390Recruiting
Testing a home sleep monitor for accuracy
This study tests a new home sleep monitoring device (TipTraQ) to see how well it works compared to the standard overnight sleep test done in a lab. It is for people who are already scheduled for a sleep study at Duke University Hospital.
Taipei, TaipeiAges 20 years+ - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT07452224RecruitingPhase 2
Combination treatment for advanced lung cancer
This trial tests a new drug, ILKN421H, combined with pembrolizumab (a type of immunotherapy) for people with advanced non-small cell lung cancer (NSCLC) that has not responded to standard treatments or has not been treated before. It aims to see if this combination can help shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT05985330Recruiting
Study of FeNO as a marker for immunotherapy response in lung cancer
This trial is testing whether a simple breath test (FeNO) can predict how well immunotherapy works in people with advanced lung cancer who haven't had treatment before. It's for patients whose tumors have high PD-L1 levels and who will receive immunotherapy alone.
DijonAges 18 years+ - NCT05350215RecruitingPhase 1/Phase 2
Testing atomoxetine and DAW2022 for obstructive sleep apnea severity
This study tests whether atomoxetine and DAW2022 can improve how severe obstructive sleep apnea is. It may help by changing breathing patterns during sleep, measured through physiology tests.
Boston, MassachusettsAges 21–70 - NCT06990477Recruiting
EIT-guided breathing machine settings for ARDS
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hefei, AnhuiAges 19–90 - NCT07603310Recruiting
PEEP levels in ARDS based on lung response
This study tests whether adjusting ventilator settings based on how well your lungs respond can improve oxygen and reduce damage in patients with moderate to severe ARDS, within the first 36 hours of diagnosis.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT07696832Recruiting
Ivonescimab as first treatment for advanced lung cancer
This trial studies ivonescimab alone as a first treatment for people with advanced non-small cell lung cancer (NSCLC) that tests positive for PD-L1 and doesn't have certain gene changes. The goal is to see if it works and is safe in everyday medical practice.
Guangzhou, GuangdongAges 18 years+ - NCT07694648Recruiting
Watching for germs that cause breathing problems
This study tracks patients with breathing problems to see which germs are making them sick. Doctors will use tests and medical records to watch for different pathogens.
Beijing, Beijing MunicipalityAges Any age - NCT07349537RecruitingPhase 1
Study of RMC-5127 for advanced KRAS G12V-mutant solid tumors
This trial tests a new drug called RMC-5127 for people with advanced solid tumors that have a specific KRAS G12V mutation. The study aims to see if this targeted therapy can help when other treatments have stopped working or caused side effects.
New Haven, ConnecticutAges 18 years+ - NCT07341737RecruitingPhase 1/Phase 2
SL-28 for advanced solid tumors that haven’t responded to treatment
This trial tests a new drug, SL-28, for people with advanced solid tumors that haven’t responded to or cannot be treated with standard therapies. It aims to find a safe dose and see if the drug can help shrink or slow the growth of your cancer.
Adelaide, South AustraliaAges 18 years+ - NCT06780098RecruitingPhase 2
Study of new treatments for advanced squamous lung cancer
This trial tests new drugs for people with advanced squamous non-small cell lung cancer that has gotten worse after standard treatments like immunotherapy and chemotherapy. The goal is to find better options for those who need them.
Lexington, KentuckyAges 18 years+ - NCT07633366Recruiting
Understanding ARDS Through Lung Fluid and Imaging Analysis
This study examines lung fluid samples and imaging scans from patients on breathing machines to better understand acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers hope this will help doctors diagnose and treat ARDS more effectively in the future.
Vienna, State of ViennaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.