Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06980038RecruitingPhase 2
Testing two immunotherapy drugs before surgery for advanced head and neck cancer
This trial tests whether adding a second immunotherapy drug (CDX-1140) to the standard immunotherapy cemiplimab before surgery is better than cemiplimab alone for people with stage III-IV head and neck cancer that can be removed with surgery.
Irvine, CaliforniaAges 18 years+ - NCT06975189RecruitingPhase 2
Reducing radiation in preterm baby lung scans
This trial tests whether using ultrasound instead of X-rays for lung imaging can safely reduce radiation exposure in very premature babies. If your baby needs lung imaging, they may be able to join.
Melbourne, VictoriaAges Up to 1 day - NCT06977581RecruitingPhase 2
Study of PF-07275315 for moderate-to-severe asthma
This study tests an investigational medicine called PF-07275315 for people with moderate-to-severe asthma that is not well controlled with current treatments. The goal is to see if it can reduce asthma attacks and improve breathing.
Mobile, AlabamaAges 18–75 - NCT06980272RecruitingPhase 3
A new drug for advanced lung cancer that hasn't been treated yet
This trial tests a new drug called SSGJ-707 for people with advanced non-small cell lung cancer who have not had prior treatment. It aims to see if the drug can help shrink tumors and improve outcomes.
ShanghaiAges 18 years+ - NCT06974851RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injectable medication (HRS9531) to see if it helps people with both obstructive sleep apnea and obesity. It compares the drug to a placebo (no active medicine) to check safety and effectiveness.
Beijing, Beijing MunicipalityAges 18–75 - NCT06975410RecruitingPhase 1/Phase 2
Trial of YH32364 for EGFR-positive solid tumors
This trial tests a new drug, YH32364, for people with advanced solid tumors that have high levels of EGFR protein. It looks at whether the drug can help when standard treatments have stopped working.
SeoulAges 18 years+ - NCT06979323RecruitingPhase 3
Depemokimab study for asthma with imaging and bronchoscopy
This study tests depemokimab, an injectable biologic, to see how it works in the lungs of people with severe asthma. You would get the drug and have special imaging and a bronchoscopy (a tube with a camera placed into your airways to take tiny tissue samples) so doctors can understand how the medicine reduces inflammation.
Brooksville, FloridaAges 18 years+ - NCT06975553Enrolling by invitation
Using a carbon dioxide monitor to guide safe breathing-tube removal
This study tests a special carbon dioxide monitor to help decide when it's safe to remove your breathing tube after abdominal surgery. If you are having a planned abdominal procedure lasting 1–4 hours, you may be able to join.
Beijing, Beijing MunicipalityAges 18–80 - NCT06974981Recruiting
Using lung cancer screening to find and treat COPD
This study looks at how lung cancer screening can also help find and manage COPD, a lung condition that often goes undetected. If you are a current or former smoker and meet certain age and smoking history criteria, you may join to help improve screening and care for both lung cancer and COPD.
Philadelphia, PennsylvaniaAges 50–80 - NCT06972784Recruiting
Heart and lung health study at Xiangya Hospital
This study looks at how heart and lung function are related over time. You may be able to join if you have had both a heart test (like an echo) and a lung test (like a breathing test) within one year of each other, and if your medical records are complete.
Changsha, HunanAges Any age - NCT06974604RecruitingPhase 2
Mouthwash to prevent mouth sores from Datopotamab deruxtecan
This trial tests if a dexamethasone mouthwash can prevent painful mouth sores (stomatitis) caused by the cancer drug Datopotamab deruxtecan (Dato-DXd). It's for people with certain types of advanced lung or breast cancer who have already tried other treatments.
Providence, Rhode IslandAges 18 years+ - NCT06976762Enrolling by invitation
Light-based muscle oxygen measurements in COPD with kidney disease
This study uses a special light-based device (near-infrared spectroscopy) to measure muscle oxygen levels in people who have both COPD and chronic kidney disease. Researchers want to see if these measurements can help predict how the disease progresses, which could lead to better monitoring and treatment.
Tokat ProvinceAges 18–80 - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT06973928Recruiting
Does adenotonsillectomy improve mouth opening and quality of life?
This study looks at whether removing the tonsils and adenoids helps children with mild sleep apnea open their mouths wider and feel better overall.
Saint-Jean-de-VédasAges 3–7 - NCT06979141RecruitingPhase 3
Cough prevention after general anesthesia
This trial compares three drugs (dexmedetomidine, magnesium sulfate, and lidocaine) to see which best prevents coughing when waking up from anesthesia. It is for adults between 21 and 60 who are having surgery and are in good general health.
AsyutAges 21–60 - NCT06981169Recruiting
Using inflammation tests to diagnose asthma in kids and adults
This trial uses a simple inflammation test (inflammometry) to help diagnose asthma more accurately in people aged 6 and older who have been sent by their primary care doctor for standard breathing tests. It aims to improve the diagnosis process and reduce delays.
Montreal, QuebecAges 6 years+ - NCT06969612RecruitingPhase 1
New drug combo as first treatment for advanced lung cancer
This trial tests a new combination of three medicines (Golidocitinib, Tislelizumab, and chemotherapy) as the first treatment for advanced non-small cell lung cancer (NSCLC). It is designed for people whose tumors have at least 1% PD-L1 and who have not had any previous treatment for advanced disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06929936RecruitingPhase 2
Trilaciclib plus docetaxel for advanced lung cancer (second-line+)
This trial tests a new drug combination (trilaciclib plus docetaxel) for people with advanced lung cancer (NSCLC) whose cancer has progressed after at least one prior treatment. The goal is to see if adding trilaciclib helps the chemotherapy work better with fewer side effects.
Xiamen, FujianAges 18 years+ - NCT06697951Recruiting
Testing the Neovent breathing device for newborns
This study tests a simple breathing machine called the Neovent for newborns with mild to moderate breathing trouble in hospitals with limited resources. It aims to see if the device can help babies breathe easier without needing a breathing tube.
Tānsen, Palpa DistrictAges 1 minute–4 weeks - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT06966284Recruiting
Study Comparing Two Antibiotics for Resistant Infections
This study looks at two strong antibiotics, polymyxin B and colistin, given through a vein to treat serious infections like pneumonia or blood infections caused by bacteria that are resistant to many other antibiotics. The goal is to see how well they work and how safe they are.
TaipeiAges 18 years+ - NCT06971796Recruiting
EURO-STIM Registry for Inspire implant users
This study gathers information from people who have or will receive an Inspire implant for sleep apnea. By joining, you help doctors learn how well the therapy works over time.
KlagenfurtAges 18 years+ - NCT06962865RecruitingPhase 2
RC108 and Furmonertinib for first-line treatment of EGFR-mutated and MET-positive NSCLC
This trial tests whether a combination of two drugs, RC108 and Furmonertinib, can help people with non-small cell lung cancer (NSCLC) that has specific genetic changes (EGFR mutation and MET positivity) and cannot be removed by surgery. It is for people who have not yet received treatment for their advanced or metastatic cancer.
BeijingAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.