Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT07138898RecruitingPhase 2
Managing immune medications for shoulder replacement in rheumatology patients
This trial tests two ways of managing your immunosuppressant medication around the time of shoulder replacement surgery. The goal is to see if one approach leads to fewer infections while still controlling your rheumatic disease.
New York, New YorkAges 18 years+ - NCT06895148Recruiting
Better breathing with lung-protective ventilation
This trial tests a way to deliver lung-protective ventilation (a method that uses low air volumes to avoid lung injury) to adults on breathing machines. It aims to see if this approach leads to better outcomes.
Minneapolis, MinnesotaAges 18 years+ - NCT06825078Recruiting
Lung MRI with synthetic CT for monitoring lung nodules
This study tests whether using an MRI combined with a special type of CT scan can effectively monitor lung nodules over time. It may help people at high risk for lung cancer avoid repeated radiation from regular CT scans.
PessacAges 55–74 - NCT07206745Recruiting
Chinese and Western medicine for severe pneumonia from drug-resistant bacteria
This trial tests a combination of traditional Chinese and Western medicine for adults with severe pneumonia caused by bacteria that are resistant to multiple antibiotics. It aims to see if this combined approach can improve treatment outcomes.
Zhengzhou, HenanAges 18–80 - NCT06880016Recruiting
Lung ultrasound after surfactant in preterm babies
This study uses lung ultrasound to see how different ways of giving surfactant (a medicine for breathing problems) affect preterm babies born before 32 weeks. It may help doctors choose the best method for your baby.
Konya, KaratayAges 1 day–5 days - NCT05890911Enrolling by invitation
Studying dopamine pathways in breathing problems during sleep
This study looks at how dopamine-related brain pathways may be involved in sleep-related breathing problems. It may help researchers better understand what causes these conditions and how to evaluate them with sleep testing.
WroclawAges 18–80 - NCT03192267Recruiting
Study of lung changes in early rheumatoid arthritis
This study looks at lung health in people with early rheumatoid arthritis (RA). It may help doctors understand how RA affects the lungs soon after diagnosis and guide better care.
Omaha, NebraskaAges 19–90 - NCT06486142RecruitingPhase 3
Comparing targeted pills for EGFR-mutated lung cancer
This study tests three different targeted pills (osimertinib, afatinib, dacomitinib) in people with advanced EGFR-mutated lung cancer who haven't had targeted therapy before. The goal is to find which pill works best and has the fewest side effects.
LundAges 18 years+ - NCT06486259Recruiting
Assessing lung injury risk in ventilated patients
This study looks at the risk of lung injury in patients on a ventilator who have ARDS (a severe lung inflammation). It aims to better understand how the lungs respond and to find safer breathing settings for you.
San Juan Bautista, Buenos AiresAges 18–75 - NCT06488118Recruiting
Lung response to inhaled immune stimulant in healthy and asthma
This study tests how the lungs react to breathing in a weak immune-stimulating drug (R848). It includes healthy volunteers and people with mild to moderate asthma to see differences in airway responses.
Cambridge, CambridgeshireAges 18–60 - NCT06488495Recruiting
Exercise program for nontuberculous mycobacterium lung disease
This trial tests whether a structured exercise program can improve symptoms and quality of life in people with nontuberculous mycobacterial (NTM) lung disease. If you have a confirmed NTM lung infection and are having respiratory symptoms, this study may help you build strength and better manage your condition.
SeoulAges 40–80 - NCT06488755RecruitingPhase 3
Study of an asthma treatment for people with moderate to severe asthma
This trial tests an experimental medication called SIM0718 to see if it can improve asthma control and reduce flare-ups. It may be an option for people whose asthma is not well-controlled with their current inhaler therapy.
Beijing, Beijing MunicipalityAges 12–75 - NCT06490744Recruiting
Lung function after COVID-19 in lung transplant patients
This study looks at how lung function changed over time in lung transplant patients who had a moderate to severe COVID-19 infection. It may help doctors understand how to better care for transplant patients after a serious COVID-19 illness.
StrasbourgAges 18 years+ - NCT06491043RecruitingPhase 2
Stem cells for COPD: safety and early effectiveness study
This trial tests whether an infusion of donor stem cells can help people with moderate to severe COPD breathe easier. If you are a current or former smoker aged 40 to 80, your symptoms are stable, and your lung function meets specific targets, you may be able to join.
New Taipei CityAges 40–80 - NCT06491966Recruiting
Comparing immune responses in bacterial vs. COVID-19 sepsis
This study compares how the body's immune system responds to bacterial sepsis vs. viral sepsis (COVID-19) in intensive care unit patients. The goal is to find better ways to treat each type of life-threatening infection.
Chengdu, SichuanAges 18–90 - NCT06492421RecruitingPhase 2
Immunotherapy before surgery for lung cancer
This trial tests whether giving two immunotherapy drugs directly into the tumor before surgery can shrink non-small cell lung cancer and improve outcomes. It is for people with early-stage (IIIA) lung cancer who are candidates for surgery.
Guanzhou, GuangdongAges 18–75 - NCT06492798RecruitingPhase 1/Phase 2
Stem cells for Long COVID: a safety and effectiveness study
This study tests whether a single infusion of mesenchymal stem cells can help with Long COVID symptoms—without causing serious side effects. It’s for people who are still struggling with COVID-related health problems months after their initial infection.
ShanghaiAges 18–70 - NCT06493877Recruiting
Respiratory rehab with eccentric treadmill exercise after chest surgery
This trial tests a special type of treadmill exercise that focuses on lengthening muscles while they're under tension (eccentric exercise) to help improve breathing after chest surgery. It may help reduce shortness of breath and speed up recovery.
MadridAges 18 years+ - NCT06494085Recruiting
Finding the right breathing support for ICU patients
This study looks at how to better adjust breathing machines for people in the ICU who have low oxygen levels. It tests a new way to measure if the machine is doing too much of the work, which could help tailor support and make breathing easier.
Toronto, OntarioAges 18 years+ - NCT06494072RecruitingPhase 4
Short vs standard antibiotics for kids hospitalized with pneumonia
This trial compares a shorter course of antibiotics to the usual longer course for children hospitalized with uncomplicated bacterial pneumonia. The goal is to see if fewer days of antibiotics work just as well, which could reduce side effects and make treatment easier.
Milwaukee, WisconsinAges 3 months–18 years - NCT06494033Recruiting
CMV prevention after lung transplant based on immune status
This trial tests whether using a blood test that measures your immune system's ability to fight CMV (a common virus) can guide when to stop anti-CMV drugs after a lung transplant, aiming to prevent the virus from causing disease.
Miami, FloridaAges 18–75 - NCT06494254Recruiting
Predicting lung function after lung cancer surgery
This study looks at how well your lungs work after surgery for lung cancer. It uses special scans and breathing tests to help doctors better predict your recovery.
Saint Leonards, New South WalesAges 18 years+ - NCT06494215Recruiting
Comparing methods to measure lung air distribution in ventilated patients
This study tests different ways to measure how air is distributed in the lungs of patients on a breathing machine (ventilator) as they are being weaned off. It may help doctors better understand lung function during recovery.
São PauloAges 18 years+ - NCT06495125RecruitingPhase 2
Study of three drugs for a type of advanced lung cancer
This trial tests a combination of two targeted drugs (defactinib and avutometinib) plus an immunotherapy (nivolumab) for people with advanced lung adenocarcinoma that has a specific gene mutation (LKB1) and has stopped responding to prior immunotherapy and chemotherapy. The goal is to see if this new combination can shrink tumors or slow cancer growth.
Atlanta, GeorgiaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.