Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT05692999RecruitingPhase 3
Maintenance pembrolizumab dose study for non-squamous lung cancer
This Phase 3 trial tests two maintenance schedules (“usual” dose versus a lower dose) of pembrolizumab after your initial chemotherapy with pembrolizumab. It aims to see if the lower dose works well enough to control cancer while possibly reducing side effects.
NamurAges 18 years+ - NCT06904365Recruiting
Ovarian-sparing radiation for young women
This study tests a way to give radiation therapy that avoids the ovaries as much as possible, to help preserve fertility and hormone function in young women.
St Louis, MissouriAges 18–50 - NCT06910930Recruiting
Muscle training device for mild to moderate sleep apnea
This study tests a device that trains your mouth and throat muscles to see if it can improve mild to moderate sleep apnea. It may be an option if you are looking for a non-CPAP treatment.
Pathum ThaniAges 18 years+ - NCT06902272RecruitingPhase 2
Blood test to predict chemo-immunotherapy response in lung cancer
This trial tests whether a blood test (ctDNA) can help predict how well a combination of chemotherapy and immunotherapy (and sometimes radiation) works before surgery for non-small cell lung cancer. It aims to see if the blood test can detect small amounts of remaining cancer to guide further treatment.
Miami, FloridaAges 18 years+ - NCT06902792Enrolling by invitationPhase 1
Adebrelimab and trametinib for children with hard-to-treat LCH
This trial tests a combination of two drugs for children and teens with Langerhans cell histiocytosis (LCH) that has not responded to standard treatments or has come back after treatment. The goal is to see if the drugs can shrink lesions and improve symptoms.
Wenzhou, ZhejiangAges Up to 18 years - NCT06909201Recruiting
Lung MRI scan to study radiation treatment effects
This study uses a special MRI scan with xenon gas to see how radiation therapy affects your lungs. It may help doctors better understand treatment response and side effects.
Houston, TexasAges 18 years+ - NCT06906263Recruiting
Anesthesia safety during airway scopes in children with tracheostomy
This study looks at problems that may happen during anesthesia (medicine to put you to sleep) when children with a tracheostomy have a routine scope to check their airway. It aims to make these procedures safer for kids like you.
SolnaAges Up to 18 years - NCT06910761RecruitingPhase 2
Radiation for cancer spread to brain lining
This trial tests whether a precise type of radiation to the brain and spine (craniospinal irradiation) can help control cancer that has spread to the lining of the brain and spinal cord (leptomeningeal disease) in people with breast cancer or non-small cell lung cancer. The goal is to improve symptoms and slow disease progression.
Duarte, CaliforniaAges 18 years+ - NCT06908993RecruitingPhase 3
Tepotinib vs standard care for MET-mutated lung cancer
This trial tests a targeted pill called tepotinib against standard treatments for advanced lung cancer with a specific MET gene change. It is for people whose cancer has progressed after at least one prior therapy.
BesançonAges 18 years+ - NCT06907667Recruiting
Do timing of flu shot affect protection in kidney failure?
This study looks at whether getting a flu shot at a different time of day affects how well it works in people with chronic kidney failure, including those on dialysis or with a kidney transplant. Researchers want to see if timing can improve the body's immune response to the vaccine.
Nice, Alpes-MaritimesAges 18–100 - NCT06903780Recruiting
Survey on biologic treatments for severe asthma
This study surveys patients who have been on a biologic treatment for severe asthma for at least 6 months but not longer than 18 months. It aims to understand their experience, including those who did not respond well to the treatment.
Exeter, DevonAges 18 years+ - NCT06910800Enrolling by invitation
Self-management for patients with a chest tube
This study gathers feedback from patients and caregivers about living with an indwelling pleural catheter (a tube that drains fluid from the chest). Your input will help design a 'self-management' program so patients can feel more in control at home.
Norwich, NorfolkAges 18 years+ - NCT06910956Recruiting
Finding high-risk patients for lung cancer screening using chest X-rays
This trial uses artificial intelligence to analyze chest X-rays and identify people who may be at high risk for lung cancer and could benefit from a CT screening scan. It's designed for current or former smokers aged 50 to 77 who have had a recent chest X-ray and are not already being checked for lung cancer.
Boston, MassachusettsAges 50–77 - NCT06903052Recruiting
App for parents managing child's breathing tube symptoms
This trial tests a mobile app that helps parents care for their child who needs a breathing tube at home. The app provides support and tips for managing symptoms, so parents feel more confident and prepared.
Kowloon, KowloonAges 2–18 - NCT06908070RecruitingPhase 4
Chemoradiation, surgery, then durvalumab for stage 3 lung cancer
This trial tests if giving the immunotherapy drug durvalumab after chemoradiation and surgery helps people with stage 3 non-small cell lung cancer. You will receive standard chemoradiation, then have surgery, and then get durvalumab to see if it lowers the chance of the cancer coming back.
AmsterdamAges 18 years+ - NCT06905522RecruitingPhase 3
Tuberculosis treatment trial for new patients
This trial tests a combination of drugs for people with active tuberculosis who have not been treated before. It aims to find a better way to treat TB, even if the bacteria are resistant to some drugs.
BeijingAges 18–65 - NCT05150145Recruiting
Radiation versus observation for liver spread of small cell lung cancer
This trial compares giving liver-directed radiation to watching closely without radiation. It is for people with small cell lung cancer that has spread to the liver, to see whether radiation helps control the disease.
Guiyang, GuizhouAges 18–70 - NCT05368467Recruiting
Registry study for pulmonary hypertension patients
This is a long-term study that enrolls people who have been diagnosed with pulmonary hypertension (high blood pressure in the lung arteries). It collects medical information over time to better understand the condition and what to expect.
Guangzhou, GuangdongAges Any age - NCT06436625Recruiting
Outpatient rehab for lung cancer patients on immunotherapy
This study tests whether a structured outpatient exercise program can help people with non-small cell lung cancer who are already receiving immunotherapy. It is designed for those whose cancer is stable or responding after initial treatment.
ViennaAges 18–120 - NCT06480994Recruiting
Testing a new tool to help diagnose blood clots
This trial tests a new computer tool that helps doctors decide whether you likely have a blood clot in your leg or lung. If you have symptoms and are not already on blood thinners, you may be able to join.
Niort, SartresAges 18 years+ - NCT03175224RecruitingPhase 2
Test drug APL-101 for lung or other tumors with MET changes
This Phase 2 study tests APL-101 to shrink advanced cancers that have certain MET-related changes, including specific MET mutations, MET gene amplification, or MET fusions. It may help people whose tumors have run out of standard treatment options.
Los Angeles, CaliforniaAges 18 years+ - NCT06892197RecruitingPhase 4
Comparing two steroids for severe pneumonia
This trial compares two common steroid medicines, hydrocortisone and prednisolone, to see which works better for people with severe community-acquired pneumonia. It aims to find the best treatment to help you recover faster.
Rønne, BornholmAges 18 years+ - NCT06892210RecruitingPhase 4
Steroid comparison for COPD flare-ups
This trial compares two common steroids, hydrocortisone and prednisolone, to see which works better for treating COPD flare-ups. It may help you recover faster from a sudden worsening of your breathing.
Rønne, BornholmAges 40 years+ - NCT06899126RecruitingPhase 3
Study of a drug combo for first-line HER2-positive lung cancer
This trial tests a new combination of drugs (trastuzumab deruxtecan, pembrolizumab, and chemotherapy) as a first treatment for people with advanced non-small cell lung cancer that has high levels of the HER2 protein. The goal is to see if this combination works better than current options.
Anchorage, AlaskaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.