Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06915454Recruiting
Better imaging during cancer surgery
This trial tests a high-resolution PET-CT scan done during surgery to help surgeons see exactly where the cancer ends. It may help make sure all cancer is removed while saving healthy tissue.
Nashville, TennesseeAges 18 years+ - NCT06915441RecruitingPhase 2
Lipid infusions to improve nutrition for premature babies
This trial tests whether giving fat (lipid) infusions can improve nutrition and growth in very premature or very low birth weight babies. It may be for babies born before 28 weeks or weighing 1,000 grams or less.
Houston, TexasAges 12 hours–6 months - NCT06916481Recruiting
Pneumonia subtypes based on lung bacteria
This study looks at the germs in your lungs to understand why some people's pneumonia doesn't get better with standard antibiotics. If you are hospitalized with pneumonia and have just started treatment, you may be asked to provide a sputum sample so researchers can study your lung microbiome.
ClichyAges 18 years+ - NCT06921655Recruiting
Using pressure and muscle measurement to avoid too much breathing help in the ICU
This study tests a new way to adjust the breathing machine settings for patients who are awake and breathing on their own but still need support. The goal is to avoid giving too much help, which can make the breathing muscles weak.
Trento, TrentoAges 18 years+ - NCT06912009Recruiting
How long to treat blood clots in the lungs
This trial looks at how long people need blood-thinning medicine after a serious blood clot in the lungs. It might help doctors find the best treatment length for each person.
StrasbourgAges 18 years+ - NCT06912945Enrolling by invitation
Laser vs. standard tools for benign voice box growths
This study compares using two types of diode laser (980 nm and 450 nm) to traditional cold instruments for removing non-cancerous growths on the voice box. The goal is to see which approach works better based on the type of growth, patient factors, and laser settings.
Sohag, Sohag GovernorateAges Any age - NCT06914999RecruitingEarly Phase 1
Comparing a new scan to standard scan during head and neck cancer radiation
This trial is testing whether a newer type of PET/CT scan (F-18 NaF) can better detect blood vessel problems caused by radiation therapy than the standard scan (F-18 FDG) in people with head and neck cancer. If successful, it could lead to better ways to prevent and manage these complications.
Atlanta, GeorgiaAges 18 years+ - NCT06921993Recruiting
Study: Using Ultrasound to Guide Antibiotic Use in Childhood Pneumonia
This study tests if lung ultrasound can help doctors decide whether to use antibiotics for children with pneumonia. If your child has signs of pneumonia but is stable enough for an ultrasound, this could help avoid unnecessary antibiotics.
San Diego, CaliforniaAges 3–10 - NCT06917222Recruiting
Comparing two surgeries for narrowed windpipe
This trial compares two surgical techniques to repair a narrowed windpipe caused by injury, trauma, or long-term breathing tube use. The goal is to find which approach works best for patients who need surgery for severe or moderate narrowing.
Al MansurahAges Any age - NCT06918132RecruitingPhase 2
Cemiplimab and Fianlimab before lung cancer surgery
This trial tests whether two immunotherapy drugs (cemiplimab and fianlimab) given before surgery can help treat stage IB to IIIB non-small cell lung cancer. You must have a PD-L1 level of at least 1% and your surgeon must think the tumor can be fully removed.
Rochester, MinnesotaAges 18 years+ - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT05623319RecruitingPhase 2
Pembrolizumab plus olaparib for extensive small cell lung cancer
This Phase 2 study tests whether combining pembrolizumab and olaparib can improve outcomes in people with extensive-stage small cell lung cancer. It mainly aims to shrink tumors and help control the cancer for longer.
Meldola, Forlì CesenaAges 18 years+ - NCT06735872Recruiting
Non-invasive breathing support for broken ribs and low oxygen
This trial tests if non-invasive breathing support (a mask that helps you breathe) can improve lung healing in people with broken ribs from chest trauma who need extra oxygen. It aims to see if this treatment helps avoid the need for a breathing tube and speeds up recovery.
Lyon, RhôneAges 18 years+ - NCT06907069Enrolling by invitationPhase 4
Combined treatment for drug-resistant bacteria in lung infections
This trial tests if giving a medication (colistin) both through an IV and as a mist you breathe in works better for lung infections caused by bacteria that are hard to treat with standard antibiotics. It may help patients who have these tough bacteria and are in the hospital.
Ningbo, ZAges 18–80 - NCT06908304RecruitingPhase 3
Study of THIO + Cemiplimab vs Chemo for Advanced Lung Cancer
This trial tests a new combination of drugs (THIO and cemiplimab) against standard chemotherapy for people with advanced non-small cell lung cancer who have already tried two prior treatments including immunotherapy and platinum chemo. The goal is to see if the combination helps control the cancer better.
PoznanAges 18 years+ - NCT06905197RecruitingPhase 1
Study of DZD6008 for advanced NSCLC with EGFR mutations
This trial tests an oral drug called DZD6008 for people with advanced non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It may be an option for those who have tried other EGFR treatments or are new to treatment.
New York, New YorkAges 18 years+ - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT06903377RecruitingPhase 1/Phase 2
ZG005 plus Gecacitinib for advanced lung cancer
This trial tests a new combination of two drugs, ZG005 and Gecacitinib, for people with advanced non-small cell lung cancer that cannot be treated with surgery or radiation. The goal is to see if the combination can shrink or slow the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06907615RecruitingPhase 2
Study of HLX43 for advanced non-small cell lung cancer
This trial tests a new drug, HLX43, for people with advanced non-small cell lung cancer that has not responded to standard treatments. It aims to see if HLX43 can help shrink or control the cancer.
Houston, TexasAges 18 years+ - NCT06908421Recruiting
Smart device and inhaler for better asthma control
This study tests if using a small smart device with your Trimbow inhaler helps you use it correctly and take it as prescribed. It is for people with asthma who already use Trimbow.
Hvidovre, Capital RegionAges 18 years+ - NCT06901297RecruitingPhase 3
Raphamin for acute sinus infection in adults
This trial tests a new medicine called Raphamin for treating sudden sinus infection (acute rhinosinusitis) in adults. It compares the medicine to a placebo to see if it can reduce symptoms like facial pain and pressure when started within the first 2 days of illness.
AramilAges 18–75 - NCT02514655Recruiting
Device to control breathing-tube cuff pressure to prevent pneumonia
This trial tests a simple device that helps keep the cuff pressure on a breathing tube at the right level. The goal is to reduce the risk of pneumonia that can happen in people on a ventilator.
ParisAges 18 years+ - NCT05280132Recruiting
Testing quick tests to shorten antibiotics in severe COPD flare
This trial checks whether using fast test results (PCR from samples, a blood marker called procalcitonin, and sputum appearance) can safely reduce how long you need antibiotics during a severe COPD flare. It may help you receive fewer days of antibiotics while still controlling the infection risk.
ParisAges 18 years+ - NCT05835102Recruiting
How nutrition measures may affect COVID-19 outcomes
This study looks at nutrition-related measurements to see how they may relate to how people with COVID-19 do over time. It may help doctors better predict who is at higher or lower risk based on nutrition status.
Chongqing, Chongqing MunicipalityAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.