Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06496048RecruitingPhase 3
Testing lurbinectedin for small cell lung cancer that has returned
This trial compares a new drug combination (lurbinectedin with or without irinotecan) against the standard treatment (topotecan) for people whose small cell lung cancer has come back after initial chemotherapy. It aims to see if the new options work better.
Jilin CityAges 18 years+ - NCT06495970Recruiting
Pulmonary artery denervation for heart failure with lung hypertension
This trial tests a procedure called pulmonary artery denervation (PADN) for people with heart failure and a certain type of high blood pressure in the lungs (pulmonary hypertension Group 2). The goal is to see if using a special device called the Gradient Denervation System can help control the high pressures and improve your symptoms.
BadalonaAges 22–85 - NCT06496386Recruiting
Robot-assisted lung surgery for older adults
This trial tests whether robotic-assisted surgery for lung cancer is safe and effective in elderly patients. It may be a good option if you are older and able to undergo surgery.
Rozzano, MilanAges 18 years+ - NCT06496490RecruitingPhase 2
TQB2102 for HER2-mutated non-small cell lung cancer
This trial tests a new drug, TQB2102, for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene and has stopped responding to standard treatments. It aims to see if the drug can shrink or slow the cancer.
Fuzhou, FujianAges 18–75 - NCT06496659Recruiting
Lung segmentectomy after chemo or immunotherapy
This study tests a type of lung surgery called segmentectomy for people whose lung cancer shrank after chemotherapy or immunotherapy. The goal is to see if removing just the tumor part is safe and effective.
Chicago, IllinoisAges 18–89 - NCT06497153Recruiting
Lung ultrasound for children with sickle cell disease
This study tests whether using lung ultrasound can help doctors quickly spot and treat acute chest syndrome in children with sickle cell disease. It may lead to faster, safer care for kids in the intensive care unit.
ParisAges 1 month–17 years - NCT06497530RecruitingPhase 2
Lurbinectedin with serplulimab for extensive-stage SCLC maintenance
This trial tests a combination of two drugs, lurbinectedin and serplulimab, as maintenance therapy after initial chemotherapy for people with extensive-stage small cell lung cancer (SCLC) that hasn't spread to the brain. The goal is to see if this approach helps keep the cancer from growing for longer.
Guangzhou, GuangdongAges 18 years+ - NCT06497816Recruiting
COPD Study: Health, Thinking, and Physical Abilities
This study looks at how health knowledge, physical abilities, thinking skills, and daily habits affect quality of life in people with COPD. It aims to find ways to better support patients.
Ankara, AnkaraAges 40 years+ - NCT06498479RecruitingPhase 3
Comparing a new drug to topotecan for relapsed small cell lung cancer
This trial tests a new drug called HS-20093 against a standard drug (topotecan) for people with small cell lung cancer that has returned after initial treatment. The goal is to see which drug works better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06498986RecruitingPhase 2
BL-B01D1 plus osimertinib for EGFR-mutant lung cancer
This trial tests a new drug (BL-B01D1) combined with osimertinib (Tagrisso) for people with advanced non-small cell lung cancer that has an EGFR mutation and who have not had any previous treatment. The goal is to see if the combination works better than standard care.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06499233RecruitingPhase 4
Study on preventing pneumocystis pneumonia in autoimmune disease
This trial tests whether a preventive treatment can stop pneumocystis pneumonia (a lung infection) in people with autoimmune inflammatory rheumatic diseases who are taking steroids or other immune-suppressing medicines. It aims to find the safest and most effective way to protect you from this serious infection.
Wuhan, HubeiAges 18 years+ - NCT06499363Recruiting
Treprostinil for pulmonary hypertension in newborns
This study collects information on how well a medicine called treprostinil works and how safe it is for newborn babies with pulmonary hypertension (high blood pressure in the lungs). It is for babies who have already received this treatment as part of their regular care.
BronAges Up to 10 months - NCT06500312Recruiting
Lung cancer imaging and genetics study
This study looks at how CT scans of lung cancer can be linked to the tumor's biology and genetics. It aims to understand lung cancer better by combining imaging with lab results.
Wuhan, HubeiAges 18 years+ - NCT06500949Recruiting
Vagus nerve block to reduce cough after lung surgery
This study tests whether blocking a specific nerve in the lung can reduce coughing after having a lung tumor removed through a small camera (VATS surgery). If you're having this surgery and are generally healthy, you may be able to join.
Hangzhou, ZhejiangAges 18–70 - NCT06500455RecruitingPhase 3
Standard vs longer radiation for brain metastases
This trial compares the usual short course of radiation therapy (one session) to a longer course (up to 5 sessions) for people with cancer that has spread to the brain. The goal is to see if the longer course works better and causes fewer side effects.
Tucson, ArizonaAges 18 years+ - NCT06500481RecruitingPhase 3
Proton vs standard radiation for cancer spread to brain/spine lining
This trial compares a newer type of radiation (proton therapy) to standard radiation for people whose breast or lung cancer has spread to the lining of the brain and spinal cord. It aims to see if proton therapy can better control the disease while causing fewer side effects.
Phoenix, ArizonaAges 18 years+ - NCT06501391RecruitingPhase 2
Brain radiation plus chemo-immunotherapy for untreated NSCLC with stable brain metastases
This trial tests whether combining brain radiation with chemotherapy and immunotherapy can help people with advanced lung cancer that has spread to the brain but has not yet been treated. It is for those whose tumors do not have certain gene mutations (EGFR, ALK, ROS1).
ShanghaiAges 18 years+ - NCT06501378RecruitingPhase 2
Brain radiation plus chemotherapy and immunotherapy for lung cancer brain metastases
This trial tests a combination of radiation to the brain plus chemotherapy and immunotherapy (anti-PD-1/PD-L1) for people with newly diagnosed non-small cell lung cancer that has spread to the brain. It is for those whose tumors do not have common driver mutations and whose brain metastases are causing symptoms.
ShanghaiAges 18 years+ - NCT06501599Recruiting
AI system for spotting COVID-19 lung changes on CT scans
This trial tests an artificial intelligence tool that helps doctors identify lung changes caused by viral pneumonia, like COVID-19, on CT scans. It may lead to faster and more accurate diagnosis for patients.
MoscowAges 18 years+ - NCT06501807Recruiting
Biologics for severe nasal polyps: a French registry study
This study follows patients in France who are receiving biologic treatments for severe nasal polyps with chronic sinusitis. It collects information on how well these treatments work and their side effects over time.
LilleAges 18 years+ - NCT06503016RecruitingPhase 3
Phosphocreatine for medical emergency team patients
This study tests if a medicine called phosphocreatine helps people in the hospital who have a serious heart or lung emergency. It aims to see if the medicine can improve recovery and prevent further complications.
MilanAges 18 years+ - NCT06503146RecruitingPhase 2
New imaging tracer for detecting various cancers
This trial tests a new imaging agent, [18F]FAPI-74, which might help detect certain cancers more clearly. The scan looks for a protein called fibroblast activation protein (FAP) that is often found in tumors. If you have one of the listed cancers and are about to start treatment, this study could help doctors see where the cancer is and how it responds to therapy.
Bethesda, MarylandAges 18–120 - NCT06503432Recruiting
Does PD-L1 affect pain after lung cancer surgery?
This study looks at how a protein called PD-L1 relates to pain after lung cancer surgery. If you're having a VATS procedure, researchers want to see if PD-L1 levels affect your recovery and pain experience.
Beijing, Beijing MunicipalityAges 18–80 - NCT06503744Recruiting
Comparing two minimally invasive heat treatments for early lung cancer
This trial compares two types of radiofrequency ablation (a heat-based treatment) for early-stage lung cancer that is located in the outer parts of the lung. One approach uses a needle through the chest wall, the other uses a bronchoscope through the airways. The goal is to see which works better for people who cannot have surgery.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.