Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06709456Recruiting
Draining fluid from lungs in the ICU
This trial tests whether draining fluid that builds up around the lungs helps patients with breathing problems in the intensive care unit. You may be eligible if you are in the ICU, have at least 2 cm of fluid on an ultrasound or CT scan, and need extra oxygen or a breathing machine.
AalborgAges 18 years+ - NCT06709859RecruitingPhase 2
Afatinib plus chemo for unresectable stage III lung cancer
This trial tests whether combining afatinib (a targeted pill for EGFR mutations) with chemotherapy can shrink advanced stage III non-small cell lung cancer (NSCLC) enough to make surgery possible. It is for people whose cancer has not been treated yet and has a specific EGFR mutation.
Jinan, ShangdongAges 18 years+ - NCT06710080RecruitingPhase 3
Testing a medicine to reduce inflammation in pneumonia patients
This trial tests if a medicine called icosapent ethyl can reduce inflammation in blood vessels for adults hospitalized with pneumonia. It aims to see if this treatment can help prevent complications.
Ottawa, OntarioAges 18 years+ - NCT06711159Recruiting
Searching for a biomarker of sleepiness in severe sleep apnea
This study looks for a biological marker of severe daytime sleepiness in people with severe obstructive sleep apnea who haven't started breathing machine treatment yet. It may help doctors better understand and treat sleepiness in the future.
Koege, Regional ZealandAges 18 years+ - NCT06712745RecruitingEarly Phase 1
Personalized lung cancer radiation therapy study
This trial tests a new approach to radiation therapy for central lung cancers, giving high doses in very short bursts to see if it's safe and effective. It may be an option for people whose tumors are not too large and are in a specific central location.
Dallas, TexasAges 18 years+ - NCT06712810RecruitingPhase 1
Q702 for blood cancers and histiocytic disorders
This study tests an experimental pill called Q702 for people with certain blood cancers and related disorders (like histiocytoses, myelofibrosis, and lymphomas) that have not responded to standard treatments. It aims to see if Q702 is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT06713382RecruitingPhase 2
Saline rinse for trapped lung infections
This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.
Boston, MassachusettsAges 18 years+ - NCT06713512Recruiting
Estrogen and its effect on lung tissue in obstructive lung disease
This study looks at how the hormone estrogen affects the lungs of people with asthma or COPD. It will help researchers understand why these diseases may be different in women.
LondonAges 18–99 - NCT06714123RecruitingPhase 2
Senicapoc for worsening lung scarring
This trial tests if the drug senicapoc can help people whose lung scarring (pulmonary fibrosis) is getting worse despite standard care. It aims to slow down the decline in lung function.
Aarhus NAges 18 years+ - NCT06714149Recruiting
How nitrogen pollution affects pollen allergies
This study looks at how pollution from nitrogen in the environment affects pollen allergies in Belgium. It may help explain why your allergy symptoms change depending on where you live.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06714513RecruitingPhase 1
TB vaccine study in older adults aged 55 to 74
This study tests a new tuberculosis (TB) vaccine (ID93+GLA-SE) in healthy adults aged 55 to 74. It aims to see if the vaccine is safe and can help protect against TB, especially in people who may have latent (inactive) TB infection.
Gwangmyeong, Gyeonggi-doAges 55–74 - NCT06714721Recruiting
Magnetic diaphragm stimulation for COPD
This study tests if magnetic stimulation of the diaphragm muscle can help people with COPD breathe better. If you have had COPD for at least 6 months, are over 18, and can answer questionnaires, you may be eligible.
AnkaraAges 18 years+ - NCT06715228Recruiting
Breathing exercise for sleep apnea
This trial tests a special breathing exercise program (called Shitali) to see if it helps people with mild or moderate sleep apnea who are not obese. If you qualify, you'll learn a gentle therapy that may improve your sleep without machines or medicine.
Dokki, Giza GovernorateAges 35–55 - NCT06715306Recruiting
IV vs. Oral Antibiotics for Common Infections
This trial compares starting antibiotics through a vein (IV) to taking them by mouth for common infections like pneumonia, urinary tract infections, or skin infections (cellulitis). The goal is to see if oral antibiotics work just as well without the need for an IV line.
Aabenraa, Southern DenmarkAges 18 years+ - NCT06716437Recruiting
Prehabilitation program before lung cancer surgery
This study tests whether a short exercise and health program before lung cancer surgery can help you recover faster. You'll use a smartphone app to follow the program and track your progress.
Parkville, VictoriaAges 18 years+ - NCT06716463Recruiting
Predicting breathing support failure with wearable monitoring
This study tests if a wearable chest monitor can predict when breathing support (like a mask or nasal prongs) might stop working, so doctors can act faster. It is for hospital patients who need help breathing but are not on a breathing tube.
Toronto, OntarioAges 18 years+ - NCT06716502Recruiting
Testing a new portable breathing support device
This trial tests a new portable device that helps people breathe without using a tube in the windpipe. It may be an option for older adults who need breathing support but are not in the hospital for a sudden illness.
Lecce, ApuliaAges 65 years+ - NCT06716580Recruiting
Lung cancer screening for Asian and Latinx communities
This study uses a blood test to look for signs of lung cancer in people who have never smoked or smoked very little. It focuses on Asian and Latinx communities because certain gene changes are more common in these groups.
Boston, MassachusettsAges 40–80 - NCT06716606RecruitingPhase 3
Long-term safety of belimumab for lung disease in scleroderma and other connective tissue diseases
This study tests the long-term safety and effectiveness of belimumab for people with lung scarring caused by scleroderma or other connective tissue diseases. It is for patients who already completed a one-year study with belimumab and were not considered treatment failures.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06717295Recruiting
Blood test to find cancer early and track treatment
This study uses a blood test that looks at your platelets and immune cells to find common cancers early, and for certain cancers, to monitor how well treatment is working.
RosarioAges 40–75 - NCT06717243Recruiting
Study on gene markers in lung cancer for treatment resistance
This study looks at genetic markers in two types of lung cancer (small cell and large cell neuroendocrine) to understand why some tumors stop responding to a standard treatment that combines chemotherapy with immunotherapy. If you have one of these cancers and are about to start this treatment, you may be able to join.
New York, New YorkAges 18–85 - NCT06717659Recruiting
Probiotics for lung rehab in COPD patients
This trial tests if adding probiotics (healthy bacteria you take as a supplement) to your regular lung rehab program helps people with COPD breathe better and feel stronger.
New Taipei CityAges 18 years+ - NCT06718309RecruitingPhase 2
Chemo and immunotherapy with targeted radiation before surgery for lung cancer
This trial tests giving chemotherapy, immunotherapy, and targeted radiation before surgery for people with non-small cell lung cancer that can be removed. The goal is to see if this combination shrinks tumors and improves outcomes.
Hangzhou, ZhejiangAges 18 years+ - NCT06718972Recruiting
Lung cancer with brain lining spread: real-world treatment study
This study looks at how people with non-small cell lung cancer that has spread to the lining of the brain or spinal cord are treated in real-world clinics in China. If you have received treatment for this spread since 2018, you may be able to help doctors learn what works best.
Guangzhou, GuangdongAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.