Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06643039Recruiting
Study on hospital-acquired respiratory virus infections
This trial looks at respiratory viruses caught in the hospital. If you are an adult patient or healthcare worker with flu-like symptoms that started while in the hospital, you may help researchers learn more about these infections.
BordeauxAges 18 years+ - NCT06636734RecruitingPhase 2
Lovastatin plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding lovastatin (a cholesterol-lowering drug) to pembrolizumab (an immunotherapy) works better than pembrolizumab alone for head and neck cancer that has come back or spread. It's for people who haven't had immunotherapy before and aren't already on a statin.
Atlanta, GeorgiaAges 18 years+ - NCT06639191RecruitingEarly Phase 1
Study of a new drug for cancers expressing CD44v6
This trial tests a new radioactive drug called [177Lu]Lu-AKIR001 for patients with certain advanced cancers (like thyroid, head and neck, lung, vulvar, or cervical cancer) that have a specific protein called CD44v6 on their surface. The goal is to see if this treatment can help when standard options have stopped working.
Stockholm, Stockholm CountyAges 18 years+ - NCT06635525Recruiting
How kidney failure affects your flu shot response
This study looks at how well the flu vaccine works in people with kidney failure who are on dialysis compared to healthy people. It will help doctors understand how kidney problems affect the body’s immune response to vaccination.
MilanAges 18–70 - NCT06634199Recruiting
Immune response after chemoradiation and immunotherapy for stage III lung cancer
This study looks at how the body’s immune system responds in people with stage III lung cancer (not removable by surgery) who first get chemotherapy and radiation and then receive the immunotherapy drug durvalumab for one year. It aims to learn more about the immune response and why the treatment works better for some people.
Ferrol, A CoruñaAges 18 years+ - NCT06644144Recruiting
P4O2: A study for people with lung scarring
This study is testing a new way to track lung scarring (fibrosis) over time in people with conditions like IPF, other fibrotic lung diseases, or early signs of scarring. It might help doctors understand how the disease changes.
Amsterdam, North HollandAges 18–80 - NCT06636890Enrolling by invitation
Testing a new method for detecting certain bacteria in lung infections
This study checks if a special test (Xpert Carba-R) can find a type of drug-resistant bacteria, called CRE, in fluid from the lungs and in rectal swabs. It might help doctors treat lower respiratory tract infections more effectively.
Nanjing, JiangsuAges 18–90 - NCT05495698Recruiting
One or multiple inhalers plus app support for COPD
This trial looks at whether using one or more inhalers, together with a smartphone app, can help people manage chronic obstructive pulmonary disease (COPD) better. You may be eligible if you have COPD, need “triple therapy” (three medicine types), and can use the app and surveys.
Rotterdam, South HollandAges 40 years+ - NCT06084117Recruiting
High-flow nasal oxygen for COPD flare-ups
This study tests whether high-flow nasal oxygen (a gentle breathing support through the nose) can help people with a severe COPD flare-up. If you have high carbon dioxide and slightly acidic blood, this treatment might improve your breathing and avoid the need for a breathing tube.
DelftAges 40 years+ - NCT06508307RecruitingPhase 1
A study of an injected virus for advanced solid tumors
This trial tests a new treatment where a virus (GC001) is injected directly into a tumor. The virus is designed to attack cancer cells and may help people with advanced solid tumors that haven't responded to other treatments.
Zhengzhou, HenanAges 18–75 - NCT06621511Recruiting
OurSleepKit: Helping couples stick with CPAP therapy
This study tests a program called OurSleepKit designed to help people with sleep apnea and their partners use CPAP therapy consistently. It may be a good fit if you and your partner live together and want to improve your sleep health together.
Boston, MassachusettsAges 18 years+ - NCT05538806Recruiting
Testing NovoTTF device use in routine treatment for pleural mesothelioma
This trial studies using the NovoTTF-200T device as part of regular care for people with pleural mesothelioma when surgery that could cure the cancer isn’t an option. It may help doctors understand how well this device fits into real-world treatment and outcomes.
Gauting, BavariaAges 18 years+ - NCT05723445Recruiting
Low glycemic diet test for diabetes and body changes in CF
This trial studies whether a low glycemic load (a specific way of choosing carbohydrates) improves blood sugar control and body composition in adults with cystic fibrosis–related diabetes. It may help reduce blood sugar problems and support healthier weight and body measurements.
Boston, MassachusettsAges 18–70 - NCT06093633Recruiting
Sleep study comparing new device to standard method
This study tests a new wearable device (WP) against standard sleep testing (PSG) for people with suspected sleep problems. It may help diagnose issues like sleep apnea more comfortably.
Baltimore, MarylandAges 12–99 - NCT06622902Recruiting
How flow changes affect CO2 in preemies on high-flow breathing support
This study watches how changing the flow of air through a breathing device (high-flow nasal cannula) affects carbon dioxide levels in preemies. It helps doctors learn the safest way to adjust breathing support for fragile infants.
HaifaAges Any age - NCT06620835RecruitingPhase 2
Optimizing local treatments for ALK-positive lung cancer on brigatinib
This trial is for people with advanced ALK-positive lung cancer who are already taking the targeted therapy brigatinib and have a few remaining spots of cancer. It tests whether adding local treatments (like surgery, focused radiation, or ablation) to the remaining spots can improve outcomes.
BrestAges 18 years+ - NCT06622174RecruitingPhase 1
Pulse radiation to help immunotherapy work better in lung cancer
This trial tests if a special type of radiation (pulse radiotherapy) can help your immune system fight cancer when it's not responding well to immunotherapy. It's for people with lung cancer that has spread to five or more areas and is growing despite treatment with PD(L)-1 inhibitors.
Montreal, QuebecAges 18 years+ - NCT06620185Recruiting
Flu immunity study: Vaccination and infection in lungs
This study looks at how your lungs and lymph nodes respond to flu infection and the nasal flu vaccine. It will help researchers understand how to create better protection against the flu.
LondonAges 18–55 - NCT06630728RecruitingPhase 4
How Addictive Are Very Low Nicotine Little Cigars?
This study is testing whether little cigars with very low nicotine are less addictive than regular ones. Researchers want to see how smoking these affects your mood, cravings, and smoking behavior.
Columbus, OhioAges 21–75 - NCT06622876Recruiting
Finding unexpected blood clots in the lungs on CT scans
This study looks back at patients in the ICU who had a CT scan that unexpectedly found a blood clot in their lungs. The goal is to see how this discovery changed their treatment and what complications they may have had.
Kfar SabaAges 18–99 - NCT06626438Recruiting
Treating lung scarring by focusing on each person's problems
This study looks at how to better treat different types of lung scarring (fibrotic ILD) by focusing on each person's specific problems. It is for adults who are already being treated for a fibrotic ILD at one of two hospitals in Perth, Australia.
Perth, Western AustraliaAges 18 years+ - NCT06628531Recruiting
Lung health in patients with severe brain bleed
This trial looks at how a severe brain bleed (subarachnoid hemorrhage) might affect lung function and hyaluronic acid buildup in the lungs. It aims to find better ways to protect breathing for patients in the intensive care unit.
TianjinAges 18–80 - NCT06624540Recruiting
Reducing pneumonia in ICU patients through evidence-based nursing
This trial tests whether teaching nurses proven methods can lower the rate of ventilator-associated pneumonia (a lung infection from breathing machines) in intensive care. It aims to improve care for patients on ventilators.
DhakaAges 18 years+ - NCT06623656RecruitingPhase 2
Pre-surgery treatment comparison for non-small cell lung cancer
This trial compares two treatment approaches before surgery for non-small cell lung cancer (NSCLC): radiation plus immunotherapy versus chemotherapy plus immunotherapy. The goal is to see which combination works better to shrink the tumor before it is removed.
New York, New YorkAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.